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ClinicalTrials.gov public records Last synced Nov 13, 2026, 3:07 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 98 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Pressure support ventilation Clear all

Conditions: Sleep Apnea, Atrial Fibrillation
Interventions: Adaptive Servo-Ventilation, Usual Care; Device · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Lung Injury, Preterm Birth
Interventions: Positive End-Expiratory Pressure (PEEP); Procedure
Lead sponsor: Murdoch Childrens Research Institute; Other
Eligibility: 23 Weeks to 28 Weeks
Enrollment: 906 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 4
States / cities: Little Rock, Arkansas • San Diego, California • Indianapolis, Indiana + 1 more

Conditions: Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome (OHS), Chronic Obstructive Pulmonary Disease (COPD), Neuromuscular Diseases (NMD)
Interventions: Non-Invasive Ventilation; Device
Lead sponsor: Breas Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 4
States / cities: Scottsdale, Arizona • San Diego, California • Colorado Springs, Colorado + 1 more

Conditions: Intraoperative Ventilation
Interventions: Spontaneous ventilation, Pressure support Ventilation, Pressure control ventilation; Procedure · Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 12 Months to 5 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Premature Birth
Interventions: Seattle-PAP, Conventional bubble nasal CPAP; Device
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: Up to 30 Weeks
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Hypertension Disorders in Pregnancy, Blood Pressure Measurement in Pregnancy, Inspiratory Strength Training (IST), Pregnancy
Interventions: Exercise at 15% PI max, Exercise at 50% PI max; Other
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
Interventions: Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen; Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 9
States / cities: Tucson, Arizona • New Haven, Connecticut • Ann Arbor, Michigan + 5 more

Conditions: Respiratory Distress Syndrome
Interventions: spontaneous breathing trial; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 48 Hours to 14 Weeks
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Phialdelphia, Pennsylvania • Philadelphia, Pennsylvania

Conditions: Hypercapnic Respiratory Failure
Interventions: Average Volume-Assured Pressure Support (AVAPS), Bilevel Positive Airway Pressure Spontaneous Timed (BIPAP S/T); Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Mechanical Ventilation Complication
Interventions: Volume Support Mode Mechanical Ventilation, Assist Control Mode Mechanical Ventilation; Other
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 468 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 2
States / cities: Chicago, Illinois • Iowa City, Iowa

Conditions: Acute Mechanical Ventilatory Failure
Interventions: Weaning; Other
Lead sponsor: RML Specialty Hospital; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2011
U.S. locations: 1
States / cities: Hinsdale, Illinois

Conditions: IVH- Intraventricular Hemorrhage, Extreme Prematurity, Hypoxia Neonatal, Hyperoxia, Respiratory Insufficiency
Interventions: Delayed Cord Clamping with Low Oxygen concentration, Delayed Cord Clamping with High Oxygen concentration; Procedure
Lead sponsor: Sharp HealthCare; Other
Eligibility: 22 Weeks to 28 Weeks
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 3
States / cities: Davis, California • San Diego, California

Conditions: Respiratory Insufficiency, Infant, Newborn, Disease
Interventions: Neurally Adjusted Ventilatory Assist, Synchronized Interm. Mandatory Assist; Device
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: Up to 24 Months
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Neonatal Respiratory Distress Related Conditions
Interventions: Regular Nasal CPAP using a conventional ventilator, High Frequency Nasal CPAP; Device
Lead sponsor: University of California, Davis; Other
Eligibility: Up to 4 Months
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Obstructive Sleep Apnea, Cognitive Decline
Interventions: Positive airway pressure, Oral appliance therapy, Positional therapy; Device
Lead sponsor: California Pacific Medical Center Research Institute; Other
Eligibility: 55 Years to 85 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 4
States / cities: Tucson, Arizona • New York, New York • Pittsburgh, Pennsylvania

Conditions: Ventilator-Induced Lung Injury, Respiratory Distress Syndrome, Bronchopulmonary Dysplasia, Preterm Infant
Interventions: Mid frequency ventilation, Standard frequency ventilation; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 1 Day to 3 Days
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 2
States / cities: Birmingham, Alabama • Mobile, Alabama

Conditions: Sleep Apnea, PreDiabetes, Overweight or Obesity
Interventions: Diet and exercise coaching, CPAP Treatment; Behavioral · Other
Lead sponsor: University of Chicago; Other
Eligibility: 20 Years to 65 Years
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Mechanical Ventilation Complication
Interventions: Diaphragm Ultrasound; Procedure
Lead sponsor: Albert Einstein Healthcare Network; Other
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Acute Exacerbation of COPD
Interventions: Hemolung Respiratory Assist System, Invasive mechanical ventilation; Device
Lead sponsor: Alung Technologies; Industry
Eligibility: 40 Years and older
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 32
States / cities: Sacramento, California • Denver, Colorado • Newark, Delaware + 28 more

Conditions: Noninvasive Ventilation, Low Birth Weight
Interventions: Neurally Adjusted Ventilatory Assist, Nasal Intermittent Positive Pressure Ventilation; Device
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: Not listed
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Sleep Apnea, Obstructive, Healthy
Interventions: SLP swallowing exercises, myofunctional exercises; Other
Lead sponsor: Denise Dewald; Other
Eligibility: 40 Years to 70 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Sleep Apnea Syndromes
Interventions: Philips BiPAP AutoSV Advanced System One, Modified Philips BiPAP ASV, ResMed S7 VPAP Adapt, ResMed S9 VPAP Adapt; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Congenital Heart Disease
Interventions: High Flow Nasal Canula following extubation, Non-Invasive Positive Pressure Ventilation following extubation; Procedure
Lead sponsor: Emory University; Other
Eligibility: Up to 1 Year
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Respiratory Failure, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS)
Interventions: Mechanical Ventilation; Device
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 246 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Murray, Utah • Salt Lake City, Utah

Search by objective public record fields.

Atrial Fibrillation Recurrence in Sleep Apnea

Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial).

Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation

A Comparison of Different Ventilation Strategies in Children Using the Proseal™ Laryngeal Mask Airway

A Study to Evaluate the Efficacy of Seattle-PAP for the Respiratory Support of Premature Infants

Breathing for Two: Inspiratory Muscle Strength Training for Supporting Healthy Blood Pressure in Pregnancy

WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department

Extubation Readiness Study in Very Low Birthweight Infants

NIV for Hypercapnic Respiratory Failure: AVAPS vs S/T BIPAP

Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

Weaning From Prolonged Mechanical Ventilation

Delayed Cord Clamping With Oxygen In Extremely Low Gestation Infants

Randomized Crossover of NAVA and Synchronized Intermittent Pressure Ventilation in Neonates and Infants

Oscillatory Versus Non-oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome

Technology-Supported Treatment of Sleep Apnea in Prediabetes

Change In Diaphragmatic Thickness Predicts Extubation Success

Extracorporeal CO2 Removal With the Hemolung RAS for Mechanical Ventilation Avoidance During Acute Exacerbation of COPD

Noninvasive NAVA Versus NIPPV in Low Birthweight Premature Infants

Swallowing in OSA & CPAP Intolerance

Servo-Ventilation In-lab PSG Evaluation

HFNC vs NIPPV Following Extubation

Airway Pressure Release Ventilation (APRV) Versus AC/VC Conventional Ventilation