- Conditions
- Osteoarthritis of the Knee
- Interventions
- Instrument
- Other
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
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Showing 1–24
of 83
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Knee Arthropathy
- Interventions
- Primary Robotic-Assisted Total Knee Arthroplasty with a short tourniquet time, Primary Robotic-Assisted Total Knee Arthroplasty with the use of a tourniquet
- Other
- Lead sponsor
- University of Louisville
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Total Knee Arthroplasty (TKA)
- Interventions
- Total IntraVenous Anesthesia (TIVA), Spinal-Block, Electroencephalogram (EEG)
- Combination Product · Device
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- knee arthroplasty, standard polyethylene, knee arthroplasty, XLP polyethylene
- Device
- Lead sponsor
- Chapel Hill Orthopedics Surgery & Sports Medicine
- Other
- Eligibility
- Not listed
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2019
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Knee Osteoarthritis, Musculoskeletal Disease, Surgery
- Interventions
- PAI, PAI + steroid, PAI + zilretta
- Drug
- Lead sponsor
- Walter Reed National Military Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Juvenile Rheumatoid Arthritis, Avascular Necrosis of Bone
- Interventions
- Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2007
- U.S. locations
- 2
- States / cities
- Billings, Montana • Vancouver, Washington
- Conditions
- Arthropathy of Knee, Arthropathy of Hip
- Interventions
- Mako Robotic-Arm Assisted Arthroplasty
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 950 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2037
- U.S. locations
- 5
- States / cities
- Jacksonville, Florida • Louisville, Kentucky • New York, New York + 2 more
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Femoral nerve catheter and sciatic nerve block, Adductor canal catheter and selective tibial block, Adductor canal catheter only
- Drug
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- YM150, Warfarin
- Drug
- Lead sponsor
- Astellas Pharma Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 685 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 44
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Tuscon, Arizona + 35 more
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Total Knee Arthroplasty
- Procedure
- Lead sponsor
- Cincinnati Sportsmedicine Research and Education Foundation
- Other
- Eligibility
- 20 Years to 65 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Total Knee Arthoplasty
- Interventions
- total knee arthroplasty, Tobramycin, Gentamicin, Antibiotic cement spacer
- Procedure · Drug · Device
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Diabetes Mellitus, Type 2, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Interventions
- Dexcom G6 Pro Continuous Glucose Monitor (CGM)
- Device
- Lead sponsor
- Stony Brook University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Stony Brook, New York
- Conditions
- Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
- Interventions
- Tourniquet Cuff Pressure
- Procedure
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016
- U.S. locations
- 2
- States / cities
- Bermuda Run, North Carolina • Winston-Salem, North Carolina
- Conditions
- Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
- Interventions
- Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA, Local Infiltration Analgesia (LIA), Bupivacaine liposome injectable suspension (IPSA block), Bupivacaine liposome injectable suspension (LIA)
- Procedure · Drug
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Revision Total Knee Arthroplasty
- Interventions
- ATTUNE Revision Knee System in Revision Total Knee Arthroplasty
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2029
- U.S. locations
- 16
- States / cities
- San Diego, California • Denver, Colorado • Fort Collins, Colorado + 13 more
- Conditions
- Knee Replacement Surgery, Osteoarthritis, Knee
- Interventions
- Epidiolex oral solution, Placebo
- Drug · Other
- Lead sponsor
- Chad Brummett
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 380 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 2
- States / cities
- Ann Arbor, Michigan • Detroit, Michigan
- Conditions
- Total Knee Arthroplasty (Replacement)
- Interventions
- 4975, 15 and 5 mg, Placebo Comparator, 4975 - 5 mg
- Drug
- Lead sponsor
- Anesiva, Inc.
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 214 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 25
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Sheffield, Alabama + 20 more
- Conditions
- Pain, Postoperative
- Interventions
- Zynrelef (Bupivacaine 60 MG / Meloxicam 1.8 MG) Per 2.3 ML Extended Release Solution, Bupivacaine HCl 0.5% Injectable Solution, primary total knee replacement
- Drug · Procedure
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Infection, Surgical Site
- Interventions
- Intraosseous Vancomycin Injection, Intravenous Vancomycin
- Drug
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 19 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Arthropathy of Knee Joint
- Interventions
- Vancomycin
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Scottsdale, Arizona
- Conditions
- Postoperative Pain, Inflammation, Osteoarthritis
- Interventions
- Dexamethasone 10 mg, Dexamethasone 20 mg, Standard multimodal pain management regimen, Placebo
- Drug
- Lead sponsor
- Thomas L Bradbury
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Tucker, Georgia
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Other Inflammatory Arthritis, Post-Traumatic Arthritis, Juvenile Rheumatoid Arthritis, Avascular Necrosis
- Interventions
- Total Knee Arthroplasty, Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 149 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2007
- U.S. locations
- 3
- States / cities
- Greensboro, North Carolina • Austin, Texas • Lakewood, Washington
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic
- Interventions
- MOTO Medial® UKA
- Device
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 269 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2025
- U.S. locations
- 5
- States / cities
- Lady Lake, Florida • Louisville, Kentucky • Billings, Montana + 2 more
- Conditions
- Osteoarthritis
- Interventions
- Total and Unicompartment Knee Replacement
- Device
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Leesburg, Florida