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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Prolapse Repair Clear all
Completed Phase 4 Interventional Results available

Phenylephrine Versus Eyelid Taping for Muller's Muscle-Conjunctival Resection (MMCR) Evaluation

NCT05890027
View directory record Official record
Conditions
Ptosis, Eyelid
Interventions
Phenylephrine Ophthalmic, Eyelid Tape
Drug · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 5, 2026, 6:42 AM EDT
Completed Not applicable Interventional

Evaluating Sexual Function After Vaginal Repair With Perineorrhaphy

NCT01779739
View directory record Official record
Conditions
Sexual Function
Interventions
Perineorrhaphy
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
19 Years to 105 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Birmingham, Alabama • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Sep 5, 2026, 6:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Difference in Pain, Quality of Life Following Vaginal Hysterectomy With Vaginal Reconstruction Versus Robotic Colpopexy?

NCT02049996
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Sep 5, 2026, 6:42 AM EDT
Recruiting No phase listed Observational

Patient-Centered Approach for Treatment Decisions in Mitral Valve Prolapse

NCT06738537
View directory record Official record
Conditions
Mitral Valve Prolapse
Interventions
Focus Groups/Quantitative Survey for Patients, Focus Group/Quantitative Survey for HCPs, Qualitative Focus Group
Other
Lead sponsor
Northwell Health
Other
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Kansas City, Missouri • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2024 · Synced Sep 5, 2026, 6:42 AM EDT
Terminated No phase listed Observational

Collection of Long Term Patient Outcomes Data Following Implantation of AMS Surgical Devices

NCT01673360
View directory record Official record
Conditions
Female Stress Incontinence, Pelvic Organ Prolapse
Interventions
Elevate PC, Mini Arc Pro, RetroArc
Device
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
18 Years and older · Female only
Enrollment
401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
6
States / cities
Alpharetta, Georgia • Morristown, New Jersey • Winston-Salem, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2016 · Synced Sep 5, 2026, 6:42 AM EDT
Completed No phase listed Observational

Comparison of 2 Lightweight Y-meshes After Laparoscopic Sacrocolpopexy

NCT02248935
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
Female only
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Sep 5, 2026, 6:42 AM EDT
Completed Not applicable Interventional Results available

Surgical Study Comparing 2 Procedures for the Treatment of a Dropped Bladder

NCT00271102
View directory record Official record
Conditions
Prolapse
Interventions
anterior vaginal repair (colporrhaphy), abdominal paravaginal defect repair
Procedure
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Sep 5, 2026, 6:42 AM EDT
Completed No phase listed Observational

Restorelle® Mesh Versus Native Tissue Repair for Prolapse

NCT02162615
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior, Native Tissue Repair Posterior
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
810 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
33
States / cities
Agoura Hills, California • Stanford, California • Denver, Colorado + 30 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Sep 5, 2026, 6:42 AM EDT
Completed Not applicable Interventional

Impact of Level III Support Procedure on Enlarged Genital Hiatus After Minimally Invasive Sacrocolpopexy

NCT04480671
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Level III support procedure, Minimally Invasive Sacrocolpopexy, Transperineal ultrasound of the Pelvic Floor
Procedure · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 5, 2026, 6:42 AM EDT
Completed No phase listed Observational Results available

Pelvic Floor Repair Systems for Prolapse Repair

NCT00638235
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
AMS Apogee™ with IntePro, AMS Apogee™ with Intexen LP, AMS Perigee™ with IntePro, AMS Perigee™ with IntePro Lite, AMS Apogee™ with IntePro Lite, AMS Elevate™ Apical & Posteiror with IntePro Lite, AMS Elevate™ Apical & Posteiror with IntXen LP, AMS Elevate™ Anterior & Apical with IntePro Lite (Gen 1, For Study Use Only), AMS Elevate™ Anterior & Apical with IntePro Lite (Gen 2)
Device
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
21 Years and older · Female only
Enrollment
725 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
17
States / cities
Downey, California • Wellington, Florida • Alpharetta, Georgia + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2016 · Synced Sep 5, 2026, 6:42 AM EDT
Completed Phase 4 Interventional Results available

Intraperitoneal Bupivacaine for Pelvic Organ Prolapse

NCT06120530
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Bupivacaine, Saline
Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Carmel, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 19, 2025 · Synced Sep 5, 2026, 6:42 AM EDT
Active, not recruiting Not applicable Interventional Results available

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design

NCT02676973
View directory record Official record
Conditions
Visceral Prolapse
Interventions
Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
10
States / cities
Birmingham, Alabama • San Diego, California • Albuquerque, New Mexico + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 5, 2026, 6:42 AM EDT
Recruiting Not applicable Interventional

PRIMARY Ancillary Substudy

NCT07103733
View directory record Official record
Conditions
Mitral Valve Prolapse, Left Ventricular Fibrosis, Ventricular Arrhythmias
Interventions
Cardiac Magnetic Resonance Imaging, ZioPatch Monitoring, Myocardial Tissue Biopsy
Procedure · Device
Lead sponsor
Annetine Gelijns
Other
Eligibility
60 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
16
States / cities
Los Angeles, California • San Francisco, California • Stanford, California + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 5, 2026, 6:42 AM EDT
Not listed Phase 4 Interventional

Surgical Intervention With DermaPure vs Native Tissue in Pelvic Organ Prolapse

NCT03939715
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
DermaPure®, native tissue
Biological · Procedure
Lead sponsor
Colorado Pelvic Floor Consultants
Industry
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Sep 5, 2026, 6:42 AM EDT
Completed Not applicable Interventional Results available

Efficacy Study of Vaginal Mesh for Prolapse

NCT00475540
View directory record Official record
Conditions
Pelvic Organ Prolapse, Uterine Prolapse, Vaginal Prolapse, Cystocele, Rectocele
Interventions
synthetic monofilament polypropylene mesh
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
21 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 11, 2022 · Synced Sep 5, 2026, 6:42 AM EDT
Recruiting Not applicable Interventional

SORE Study: Sitz Baths After Urogynecologic Reconstruction

NCT07215780
View directory record Official record
Conditions
Pelvic Organ Prolapse, Postoperative Pain Management, Gynecologic Surgeries
Interventions
Sitz Bath
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Bridgeport, Connecticut • Greenwich, Connecticut • New Haven, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 5, 2026, 6:42 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse

NCT07213635
View directory record Official record
Conditions
Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic, Postoperative Pain
Interventions
Bupivacaine-epinephrine, Normal saline
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 5, 2026, 6:42 AM EDT
Completed Not applicable Interventional

Endoluminal and Needlescopic Assisted Repair of Rectal Prolapse

NCT01980043
View directory record Official record
Conditions
Rectal Prolapse
Interventions
endoluminal rectal prolapse repair under sedation
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
75 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Sep 5, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis

NCT01393171
View directory record Official record
Conditions
Anterior Vaginal Wall Prolapse, Cystocele, Pelvic Organ Prolapse
Interventions
Polypropylene mesh (Polyform by Boston Scientific), Porcine Dermis (Pelvicol by CRBard), Anterior Colporrhaphy
Device · Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2018
U.S. locations
2
States / cities
Downey, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 5, 2026, 6:42 AM EDT
Terminated No phase listed Observational

Exair® Versus Native Tissue Repair for Prolapse

NCT02162628
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Exair Prolapse Repair System, Total Native Tissue Repair
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
13
States / cities
Savannah, Georgia • Fort Wayne, Indiana • Dearborn, Michigan + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Sep 5, 2026, 6:42 AM EDT
Completed Not applicable Interventional Results available

Retropubic vs. Single-Incision Mid-Urethral Sling for Stress Urinary Incontinence

NCT03520114
View directory record Official record
Conditions
Stress Urinary Incontinence, Pelvic Floor Disorders
Interventions
RP sling placement, SIS placement
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older · Female only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Chicago, Illinois • Manhasset, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Sep 5, 2026, 6:42 AM EDT
Terminated Not applicable Interventional

SCP vs HUSLS for Pelvic Organ Prolapse Repair

NCT02800512
View directory record Official record
Conditions
Pelvic Organ Prolapse, Cystocele, Rectocele, Enterocele
Interventions
Robotic sacrocolpopexy, high uterosacral ligament suspension
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 5, 2026, 6:42 AM EDT
Completed No phase listed Observational

Colpocleisis for Advanced Pelvic Organ Prolapse

NCT00271037
View directory record Official record
Conditions
Pelvic Organ Prolapse, Stress Urinary Incontinence
Interventions
Colpocleisis prolapse repair surgery, sling or other to treat or prevent stress incontinence
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
21 Years and older · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
6
States / cities
Birmingham, Alabama • Maywood, Illinois • Iowa City, Iowa + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2011 · Synced Sep 5, 2026, 6:42 AM EDT
Completed Not applicable Interventional Results available

Xenform Postmarket Surveillance Study

NCT01945580
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Prolapse Repair
Procedure
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older · Female only
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
25
States / cities
Orange, California • Atlanta, Georgia • Augusta, Georgia + 21 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Sep 5, 2026, 6:42 AM EDT