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Conditions: Atrial Fibrillation, Catheter Ablation
Interventions: Protamine Sulfate; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Healthy Volunteers
Interventions: Fast release BRB confection, Intermed release BRB confection, Prolong release BRB confection; Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Complications of Bariatric Procedures, Avitaminosis
Interventions: Chewable Multivitamin with Iron, PatchMD Vitamin D3/Calcium Patch, PatchMD Multivitamin Patch, PatchMD B12 Energy Plus Patch, Chewable Calcium, Quick Dissolve B12; Dietary Supplement
Lead sponsor: California State Polytechnic University, Pomona; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Brea, California

Conditions: Mallet Fracture, Metacarpal Fracture, Metacarpal Neck Fracture, Distal Radius Fracture, Radial Head Fracture
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: HIV, HIV Linkage to Care, HIV Testing, HIV Treatment
Interventions: COAST-AL; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 13 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Healthy
Interventions: Leptin administration, Fasting; Drug · Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2003
U.S. locations: 2
States / cities: Boston, Massachusetts • Cambridge, Massachusetts

Conditions: Jet Lag Disorder
Interventions: Transmeridian travel across multiple time zones; Other
Lead sponsor: Vanda Pharmaceuticals; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 119 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Santa Monica, California • Chevy Chase, Maryland

Conditions: Migraine Headache
Interventions: Stress, Fasting; Behavioral · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Vestibular Hypofunction, Binocular Vision Abnormalities, Reduced Vision
Interventions: StableEyes: Incremental Vestibulo-Ocular Reflex Adaptation (IVA); Device
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Acute Ischemic Stroke
Interventions: C-Arm Cone Beam Computed Tomography, Multi-detector Computed Tomography; Diagnostic Test
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Infection, Human Immunodeficiency Virus
Interventions: GSK2838232, Placebo, Ritonavir; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: PAD - Peripheral Arterial Disease, Vascular Diseases, Wounds
Interventions: PIUR tUS Imaging System; Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Lake Success, New York

Conditions: Diabetes Type 2
Interventions: Technosphere® Insulin Inhalation Powder, 70% insulin aspart protamine suspension and 30% insulin aspart injection (rDNA origin); Drug
Lead sponsor: Mannkind Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 677 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 80
States / cities: Mobile, Alabama • Tucson, Arizona • Chula Vista, California + 54 more

Conditions: Diagnoses Disease
Interventions: HemoTypeSC; Device
Lead sponsor: Silver Lake Research Corporation; Industry
Eligibility: Not listed
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Azusa, California

Conditions: Obesity
Interventions: Condition A (see detailed summary), Condition B (see detailed summary), Condition C (see detailed summary); Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 13 Years to 17 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Heart Failure, Dyspnea
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 375 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Healthy
Interventions: OROS methylphenidate hydrochloride, methylphenidate hydrochloride; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Treatment Resistant Depression, MDD, Major Depressive Disorder, Recurrent Depression, Depression
Interventions: Psilocybin, Accelerated intermittent theta burst (aiTBS) rTMS treatment, Low-dose psilocybin, Sham Accelerated intermittent theta burst (aiTBS) rTMS treatment; Drug · Device
Lead sponsor: University of Texas at Austin; Other
Eligibility: 22 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Evidence of Ruptured Membranes in Women Greater Than 15 Weekd
Interventions: Not listed
Lead sponsor: Louisiana State University, Baton Rouge; Other
Eligibility: 18 Years and older · Female only
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Intubation, Intratracheal, Rapid Sequence Induction and Intubation, Checklist
Interventions: Intubation Checklist, Standard Care; Other
Lead sponsor: Community Medical Center, Toms River, NJ; Other
Eligibility: 18 Years and older
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Toms River, New Jersey

Conditions: Diabetes Mellitus, Type 2
Interventions: Insulin Pump (Medtronic Minimed Paradigm® VEO); Device
Lead sponsor: Medtronic MiniMed, Inc.; Industry
Eligibility: 30 Years to 75 Years
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 3
States / cities: Atlanta, Georgia • Albany, New York • Syracuse, New York

Conditions: Alopecia Areata
Interventions: MedJet Device with intralesional triamcinolone; Combination Product
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 6 Years to 17 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Immunotherapy-related Pruritus
Interventions: TriCalm Hydrogel®, Triamcinolone acetonide 0.1% cream; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Bioavailability
Interventions: Naproxen sodium; Drug
Lead sponsor: Bayer; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 1
States / cities: Little Rock, Arkansas

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Use of Protamine for Heparin Reversal After Catheter Ablation of Atrial Fibrillation

Black Raspberry Confection in Preventing Oral Cancer in Healthy Volunteers

Vitamin Supplementation After Bariatric Surgery

Optional Follow-up Visits for Common, Low-risk Arm Fractures

Implementation Trial to Evaluate a Population Health Combination Intervention to Meet HIV Testing, Linkage, and Viral Suppression Goals in Alabama

Secondary Analysis of Gut Hormones and Inflammatory Cytokines in Fasting Subjects

An Observational Study to Investigate the Effects of Rapid Transmeridian Travel

Acute Stress Response in Migraine Sufferers

Visual Influences on Vestibular Adaptation

C-arm Cone Beam CTP Guided Cerebrovascular Interventions

A Repeat Dose Pharmacokinetic (PK) and Safety Study of GSK2838232 With and Without Ritonavir (RTV) Conducted in Healthy Subjects

Examining the Use of Three Dimensional Ultrasound in the Assessment of Vascular Pathologies

Efficacy and Safety in Subjects With Type 2 Diabetes Receiving Subcutaneous Basal Insulin and Prandial Inhalation of Technosphere/Insulin Versus Subcutaneous Premixed Insulin Therapy Over a 52-Week Treatment Period and a 4-Week Follow-up

Evaluation of HemoTypeSC as a Novel Rapid Test for Point-of-Care Screening for Sickle-Cell Disease, Hemoglobin C Disease, and Carrier Status in Low-Resource Settings

Fast Food Feeding in Youth

Bedside Ultrasound Identifies Congestive Heart Failure

Study Examining Repeat Dosing of OROS® Methylphenidate (CONCERTA®) and Immediate Release Methylphenidate in Healthy Adults

Psilocybin rTMS for Treatment Resistant Depression

A Comparison of Rapid Immunoassays for the Detection of Ruptured Membranes

Community Medical Center, Continuous Quality Improvement Project, Rapid Sequence Intubation

OpT2mise Glucose Control in Type 2 Diabetes Mellitus (DM) With Insulin Pump Therapy

Needle-free Delivery of Intralesional Triamcinolone for Pediatric Alopecia Areata

TriCalm Hydrogel® in the Treatment of Immunotherapy-Related Pruritus

Fast & Fed Pharmacokinetic (PK) Study