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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: RF Non-Invasive Treatment Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

TriActive+ Radiofrequency (RF) for Non-Invasive Treatment of Wrinkles and Rhytides

NCT01859611
View directory record Official record
Conditions
Wrinkles, Rhytides
Interventions
TriActive+ RF
Device
Lead sponsor
El. En. SpA
Industry
Eligibility
30 Years to 60 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
Indianapolis, Indiana • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of the Safety and Efficacy of a 1060 nm Diode Laser (Flanks)

NCT03756168
View directory record Official record
Conditions
Fat Atrophy
Interventions
1060nm Diode laser
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Sacramento, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Results available

Post Market Clinical Follow Up Study to Collect Additional Data and Imaging

NCT04881058
View directory record Official record
Conditions
Pigmentation, Wrinkle
Interventions
RF Non-Invasive Treatment
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Montclair, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Sep 5, 2026, 1:39 PM EDT
Withdrawn Phase 4 Interventional

The PRIORi-T Trial--Prospective Randomized Investigation of Radiofrequency Targeted Vertebral Augmentation

NCT01480167
View directory record Official record
Conditions
Painful Osteoporotic Vertebral Compression Fractures (VCF)
Interventions
Vertebral Augmentation (STABILIT), Non-operative Management
Device · Other
Lead sponsor
DFINE Inc.
Industry
Eligibility
21 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
6
States / cities
St Louis, Missouri • Lebanon, New Hampshire • Mineola, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles

NCT03831477
View directory record Official record
Conditions
Rhytides, Wrinkle
Interventions
Venus Viva
Device
Lead sponsor
Venus Concept
Industry
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a 1060 nm Diode Laser, PEMF and Vacuum Assisted MP RF for Non-invasive Fat Reduction

NCT04012814
View directory record Official record
Conditions
Adipose Tissue Atrophy
Interventions
Venus Bliss
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
5
States / cities
Los Altos, California • Sacramento, California • Santa Monica, California + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 5, 2026, 1:39 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Subject Evaluation of a 1064nm Diode Laser/RF

NCT04090853
View directory record Official record
Conditions
Subcutaneous Fat Disorder
Interventions
Venus Bliss
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Denver, Colorado • Foxborough, Massachusetts • Woodmere, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2023 · Synced Sep 5, 2026, 1:39 PM EDT
Not listed Not applicable Interventional

Clinical Study to Evaluate Alexandrite Laser for the Treatment of Acne Scars

NCT04807179
View directory record Official record
Conditions
Acne Scars
Interventions
Experimental: RF Device Arm
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Los Angeles, California • New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Sep 5, 2026, 1:39 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Electrical Muscle Stimulation with 1064 Nm Diode Laser and RF/PEMF for Non-invasive Body Contouring and Fat Reduction.

NCT05256771
View directory record Official record
Conditions
Fat Reduction, Muscle Tone Increased
Interventions
EMS, 1064 nm diode laser, RF/PEMF
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
3
States / cities
San Diego, California • Hackensack, New Jersey • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

TriActive+ Radiofrequency (RF) for Non-invasive Treatment of Wrinkles & Rhytides

NCT01460927
View directory record Official record
Conditions
Wrinkles, Rhytides
Interventions
TriActive+ RF
Device
Lead sponsor
Deka Medical, Inc.
Industry
Eligibility
30 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Vancouver, Washington
Source: ClinicalTrials.gov public record
Updated Jul 3, 2014 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multi-Center Pivotal Study of Radiofrequency Device

NCT04569253
View directory record Official record
Conditions
Body Fat
Interventions
TempSure
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
6
States / cities
Hunt Valley, Maryland • New York, New York • Rye, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2022 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Efficacy of Combined EMS and RF Treatments

NCT04124419
View directory record Official record
Conditions
Non-invasive Circumference Reduction
Interventions
Treatment with Evolve System
Device
Lead sponsor
InMode MD Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Reno, Nevada • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 5, 2026, 1:39 PM EDT
Not listed No phase listed Observational

Bridging Therapy in Patients at High Risk for Stent Thrombosis Undergoing Surgery

NCT00653601
View directory record Official record
Conditions
Bleeding, Thrombosis
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 3, 2009 · Synced Sep 5, 2026, 1:39 PM EDT
Terminated Not applicable Interventional Results available

Histological Study on Safety and Efficacy of a RF Device Flexible Applicator for Non-Invasive Lipolysis

NCT04881175
View directory record Official record
Conditions
Lipolysis
Interventions
Non-Invasive Treatment
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Montclair, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated May 30, 2022 · Synced Sep 5, 2026, 1:39 PM EDT
Terminated Phase 3 Interventional

Mitomycin C Intravesical Chemotherapy in Conjunction With Synergo® Radiofrequency-Induced Hyperthermia for Treatment of Carcinoma in Situ Non-Muscle Invasive Bladder Cancer Patients Unresponsive to Bacillus Calmette-Guérin, With or Without Papillary Tumors.

NCT03335059
View directory record Official record
Conditions
Bladder Cancer, Bladder Neoplasm, Bladder Tumors, Cancer of Bladder, Cancer of the Bladder, Malignant Tumor of Urinary Bladder, Neoplasms, Bladder, Urinary Bladder Cancer, Carcinoma in Situ of Bladder, Papillary Carcinoma of Bladder (Diagnosis), BCG-Unresponsive Bladder Cancer
Interventions
Synergo® RITE + MMC
Combination Product
Lead sponsor
Medical Enterprises Ltd.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
4
States / cities
Hanover, Maryland • New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Sep 5, 2026, 1:39 PM EDT
Recruiting Phase 1 Interventional

EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)

NCT05723107
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Chemotherapy, Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA)
Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Results available

Post Market Study Using The Elite IQ Device

NCT04807205
View directory record Official record
Conditions
Hair Removal, Pseudo Folliculitis Barbae, Benign Vascular Lesion, Pigmented Lesions
Interventions
RF Non-Invasive Treatment
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Sep 5, 2026, 1:39 PM EDT
Active, not recruiting No phase listed Observational

A Prospective Study Comparing VivAer to Alternative Surgical Procedures to Treat Nasal Airway Obstruction in Patients With Nasal Valve Dysfunction.

NCT06922955
View directory record Official record
Conditions
Nasal Airway Obstruction
Interventions
Not listed
Lead sponsor
Aerin Medical
Industry
Eligibility
22 Years to 85 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
35
States / cities
Alexander City, Alabama • Birmingham, Alabama • Huntsville, Alabama + 27 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical and Histological Evaluation of BTL-785F Non-invasive Treatment for Facial Rejuvenation

NCT05987917
View directory record Official record
Conditions
Wrinkle
Interventions
BTL-785-2, No Treatment
Device · Other
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
21 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Sep 5, 2026, 1:39 PM EDT
Terminated No phase listed Observational

Cooled Versus Conventional Genicular Radiofrequency Ablation for Chronic Knee Pain

NCT04275128
View directory record Official record
Conditions
Chronic Knee Pain
Interventions
Cooled radiofrequency ablation, Conventional radiofrequency ablation
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Sep 5, 2026, 1:39 PM EDT
Recruiting Not applicable Interventional

RFA for Superficial Lipomas

NCT06903208
View directory record Official record
Conditions
Lipoma
Interventions
STARMed VIVA Combo RF System
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 5, 2026, 1:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles

NCT03776461
View directory record Official record
Conditions
Rhytides, Wrinkle
Interventions
Venus Viva
Device
Lead sponsor
Venus Concept
Industry
Eligibility
22 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 5, 2026, 1:39 PM EDT