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ClinicalTrials.gov public records Last synced Sep 5, 2026, 10:52 AM EDT

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Showing 1–24 of 443 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Radio-Frequency Ablation Clear all
Terminated Not applicable Interventional Results available

Atrial Pressure Electrophysiology Pilot Study

NCT01845974
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
ThermoCool® SF NAV Catheter, ThermoCool® catheter
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Sep 5, 2026, 10:52 AM EDT
Terminated No phase listed Observational

Cryoablation Versus Radiofrequency Ablation

NCT00238823
View directory record Official record
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 22, 2007 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Not applicable Interventional

Comparison of Treatments for Barrett's Esophagus With High-Grade Dysplasia/Early Adenocarcinoma

NCT01961778
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Radio-Frequency Ablation, Cryotherapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Sep 5, 2026, 10:52 AM EDT
Terminated Phase 4 Interventional Results available

Post-lesion Administration of Dexamethasone to Prevent the Development of Neuritis After Radiofrequency Ablation

NCT03247413
View directory record Official record
Conditions
Neuritis, Radiofrequency Ablation
Interventions
Dexamethasone 4 mg/ml, Normal saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Sep 5, 2026, 10:52 AM EDT
Recruiting Not applicable Interventional

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

NCT07214376
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Hypertension, Vascular Diseases, Cardiovascular Diseases, Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
Interventions
Pulmonary Artery Denervation (PADN), Sham procedure control
Device
Lead sponsor
Pulnovo Medical, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
6
States / cities
Tucson, Arizona • Houma, Louisiana • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 5, 2026, 10:52 AM EDT
Completed No phase listed Observational Results available

NAVISTAR® THERMOCOOL® SF Catheter: Observational Study

NCT01585961
View directory record Official record
Conditions
Atrial Fibrillation, Paroxysmal Arrhythmia
Interventions
Catheter Ablation (NAVISTAR® THERMOCOOL® SF Catheter)
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
511 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
45
States / cities
Huntsville, Alabama • Anchorage, Alaska • Phoenix, Arizona + 40 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Sep 5, 2026, 10:52 AM EDT
Terminated No phase listed Observational

The STAR™ Tumor Ablation Registry

NCT02419703
View directory record Official record
Conditions
Metastatic Lesions in Vertebral Bodies
Interventions
STAR™ Tumor Ablation System
Device
Lead sponsor
Merit Medical Systems, Inc.
Industry
Eligibility
22 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
15
States / cities
Concord, California • Escondido, California • Los Angeles, California + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Not applicable Interventional

Radiofrequency Ablation of Papillary Thyroid Microcarcinoma

NCT05132205
View directory record Official record
Conditions
Papillary Thyroid Cancer
Interventions
Radiofrequency Ablation
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Sep 5, 2026, 10:52 AM EDT
Terminated Not applicable Interventional Results available

The Substrate and Intervention Mechanisms for Persistent Atrial Fibrillation Trial

NCT02918396
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Scar-Based Radio-frequency Ablation, Rotor Anchors Radio-frequency Ablation, Conventional PVI by Radio-frequency Ablation
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 3, 2018 · Synced Sep 5, 2026, 10:52 AM EDT
Completed No phase listed Observational

Radiofrequency Nerve Ablation Versus Sham to Treat Chronic Low Back Pain Caused by Sacroiliac Joint Dysfunction

NCT01104051
View directory record Official record
Conditions
Sacroiliac Joint Dysfunction
Interventions
Not listed
Lead sponsor
Coastal Orthopedics & Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2015 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Phase 3 Interventional

Ablation of Perimitral Flutter Following Catheter Ablation of Atrial Fibrillation: Impact on Outcomes

NCT01173796
View directory record Official record
Conditions
Atrial Fibrillation, Perimitral Flutter
Interventions
catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2012 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Not applicable Interventional Results available

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

NCT01984346
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
AtriCure EPi-Sense-AF Guided Coagulation System with VisiTrax, Endocardial RF Catheter ablation using Open Irrigated-tip RF Abaltion Catheter with unidirectional or bidirectional steering
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Huntsville, Alabama • Denver, Colorado + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Phase 3 Interventional Results available

First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT Study)

NCT00392054
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary Vein Isolation performed by Catheter Ablation, Conventional Antiarrhythmic Drug Therapy
Procedure · Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
19 Years to 75 Years
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 30, 2020 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Phase 4 Interventional Results available

Corticosteroid Pulse After Ablation

NCT00807586
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Solumedrol, Placebo
Drug
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 5, 2026, 10:52 AM EDT
Not listed Phase 4 Interventional

Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure

NCT04160000
View directory record Official record
Conditions
Atrial Fibrillation, Heart Failure, Diastolic Heart Failure
Interventions
Catheter ablation, Rate or Rhythm control antiarrhythmic drugs for atrial fibrillation, Insertion of CardioMems Hemodynamic monitor, Empiric heart failure drug therapy
Device · Drug
Lead sponsor
Electrophysiology Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
7
States / cities
Flagstaff, Arizona • Jonesboro, Arkansas • Littleton, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Sep 5, 2026, 10:52 AM EDT
Recruiting No phase listed Observational

Safety and Efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the Treatment of Pancreatic Lesions

NCT07737171
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
60 participants
Timeline
2026 – 2033
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Phase 4 Interventional Results available

Evaluation of VISITAG SURPOINT™ Module With External Processing Unit (EPU)

NCT03624881
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Catheter ablation with EPU
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
41
States / cities
Birmingham, Alabama • Huntsville, Alabama • Little Rock, Arkansas + 34 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Sep 5, 2026, 10:52 AM EDT
Terminated Not applicable Interventional

Resection Versus Microwave Ablation for Resectable Colorectal Cancer Liver Metastases

NCT02866344
View directory record Official record
Conditions
Colorectal Neoplasms, Neoplasm Metastasis, Hepatic Neoplasms
Interventions
Microwave ablation, Hepatic resection
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Phase 4 Interventional Results available

Medical Therapy Versus Radiofrequency Endometrial Ablation in the Initial Treatment of Menorrhagia

NCT01165307
View directory record Official record
Conditions
Menorrhagia
Interventions
Estradiol 30mcg / Levonorgestrel 150mcg monophasic oral contraceptive pills, Naproxen sodium pills, NovaSure® Radiofrequency Endometrial Ablation
Drug · Device
Lead sponsor
Abimbola Famuyide
Other
Eligibility
30 Years to 55 Years · Female only
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Sep 5, 2026, 10:52 AM EDT
Recruiting Not applicable Interventional

Feasibility Study for the SIRA-1000, SIRA® RFA Electrosurgical Device as an Adjunct to Breast Conserving Surgery

NCT07206121
View directory record Official record
Conditions
Breast Cancer, Breast-conserving Surgery, Breast Cancer - Infiltrating Ductal Carcinoma, ER/PR+Her2neu, Grade I, II, III
Interventions
Radiofrequency ablation alone, Radiofrequency ablation Electrosurgical Device
Device
Lead sponsor
Innoblative Designs, Inc.
Industry
Eligibility
50 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Not applicable Interventional

MRI-Targeted Focal Ablation of the Prostate in Men With Prostate Cancer

NCT02303054
View directory record Official record
Conditions
Prostate Cancer
Interventions
Bipolar Radiofrequency Focal Ablation
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
40 Years to 80 Years · Male only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2017 · Synced Sep 5, 2026, 10:52 AM EDT
Completed Not applicable Interventional

Cryoballoon vs. Rhythmia Guided Ablation for Recurrent AFib

NCT03811795
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
ECG monitoring with a Kardia Mobile monitor
Other
Lead sponsor
Valley Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
West Des Moines, Iowa • Paramus, New Jersey • Springfield, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 5, 2026, 10:52 AM EDT
Recruiting Not applicable Interventional

RFA Using Multi-Tined Electrodes vs.Traditional Electrodes for Lumbar Spondylosis

NCT06477094
View directory record Official record
Conditions
Lumbar Spondylosis
Interventions
Stratus Nimbus Electrosurgical RF Multi-Tined Expandable Electrode, Stryker Venom Radiofrequency Cannula
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 5, 2026, 10:52 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cooled RF Lesion MRI Characteristics

NCT03631030
View directory record Official record
Conditions
Arthritis;Lumbosacral, Osteo Arthritis Knee, Sacroiliitis, Hip Osteoarthritis, Arthritis, Degenerative
Interventions
Cooled radiofrequency ablation
Device
Lead sponsor
International Spine, Pain and Performance Center
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Sep 5, 2026, 10:52 AM EDT