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Conditions: Thyroid Nodules
Interventions: Thyroidectomy, Radiofrequency Ablation; Procedure · Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Timeline: 2019 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Barrett's Esophagus
Interventions: Dexlansoprazole, Dexlansoprazole Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 6
States / cities: Jacksonville, Florida • Chapel Hill, North Carolina • Knoxville, Tennessee

Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: Radiofrequency ablation; Device
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Ventricular Tachycardia
Interventions: Radiofrequency Catheter Ablation (RFCA); Procedure
Lead sponsor: Texas Cardiac Arrhythmia Research Foundation; Other
Eligibility: 18 Years to 75 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Persistent Atrial Fibrillation
Interventions: Catheter Ablation; Procedure
Lead sponsor: Stavros E Mountantonakis; Other
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 3
States / cities: Manhasset, New York • New Hyde Park, New York • New York, New York

Conditions: Ventricular Tachycardia, Ischemic
Interventions: Drug Treatment, Catheter Ablation; Drug · Device
Lead sponsor: Biosense Webster, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 23
States / cities: Los Angeles, California • San Francisco, California • Aurora, Colorado + 14 more

Conditions: Atrial Fibrillation (AF), Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation (PAF)
Interventions: Sphere-9 Catheter Ablation; Device
Lead sponsor: Medtronic Cardiac Ablation Solutions; Industry
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 22
States / cities: Birmingham, Alabama • La Jolla, California • Los Angeles, California + 19 more

Conditions: Atrial Fibrillation, Mitral Valve Insufficiency, Mitral Valve Stenosis
Interventions: MVS, Ablation; Procedure · Device
Lead sponsor: Annetine Gelijns; Other
Eligibility: 18 Years and older
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 18
States / cities: New Haven, Connecticut • Newark, Delaware • Atlanta, Georgia + 14 more

Conditions: Liver Cancer, Metastatic Cancer
Interventions: lyso-thermosensitive liposomal doxorubicin, radiofrequency ablation; Drug · Procedure
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Low Back Pain, Chronic
Interventions: Iovera Medial Branch Cryoneurolysis, Radiofrequency ablation (RFA); Device · Procedure
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Barrett's Esophagus, GERD
Interventions: Endoscopy, Radiofrequency ablation protocol, Endoscopic mucosal resection protocol; Procedure
Lead sponsor: Valley Health System; Other
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Paramus, New Jersey

Conditions: Vasovagal Syncope, AV Block-2Nd Degree-Type 1, Sinus Pause
Interventions: Ablation procedure; Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 300 participants
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Atrial Fibrillation
Interventions: radiofrequency catheter ablation; Procedure
Lead sponsor: Texas Cardiac Arrhythmia Research Foundation; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Low Risk, Papillary Thyroid Cancer, Radiofrequency Ablation
Interventions: Questionnaire; Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Pain, Chronic Pain, Acute Pain
Interventions: Mindful Pain Management, Pain Psychoeducation; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Osteoarthritis, Knee
Interventions: Genicular nerve radiofrequency ablation, Pain Management Radiofrequency Kit; Procedure · Device
Lead sponsor: Millennium Pain Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 3
States / cities: Bloomington, Illinois • Decatur, Illinois • Peoria, Illinois

Conditions: Osteo Arthritis of Hip
Interventions: Cooled RFA treatment, Steroid Drug; Procedure · Drug
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Uterine Fibroids
Interventions: radiofrequency ablation; Procedure
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Knee Osteoarthritis
Interventions: Duloxetine, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices; Drug · Combination Product · Procedure + 2 more
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 1,937 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 24
States / cities: Sacramento, California • San Diego, California • Aurora, Colorado + 19 more

Conditions: Barrett's Esophagus, Esophageal Neoplasms
Interventions: Radiofrequency Ablation(RFA) by HALO device., Endoscopic mucosal resection(EMR) by mucosectomy kit.; Device
Lead sponsor: Midwest Biomedical Research; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 3
States / cities: Chicago, Illinois • St Louis, Missouri • New York, New York

Conditions: Colorectal Cancer, Metastatic Cancer
Interventions: positron emission tomography, radiofrequency ablation; Procedure
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Liver Cancer
Interventions: radiofrequency ablation; Device
Lead sponsor: American College of Radiology Imaging Network; Network
Eligibility: 18 Years to 120 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 18
States / cities: Birmingham, Alabama • Los Angeles, California • Sacramento, California + 13 more

Conditions: Atrial Fibrillation
Interventions: Ablation procedure staged catheter ablation; Device
Lead sponsor: AtriCure, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 4
States / cities: Stanford, California • Colorado Springs, Colorado • Nashville, Tennessee + 1 more

Conditions: Atrial Fibrillation
Interventions: Periods of Apnea, Control Arm - No Periods of Apnea; Other
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 6
States / cities: Bay Shore, New York • Manhasset, New York • New York, New York + 2 more

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RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life Study

Effect of Dexlansoprazole 60 mg QD and 60 mg BID on Recurrence of Intestinal Metaplasia in Subjects Who Have Achieved Complete Eradication of Barrett's Esophagus With Radiofrequency Ablation

Outcome of Patients With Lung Masses Who Are Treated With Radiofrequency Ablation (RFA)

Ablation of Clinical Ventricular Tachycardia Versus Addition of Substrate Ablation on the Long Term Success Rate of VT Ablation

ARIADNE Clinical Trial

Early Ablation Therapy for the Treatment of Ischemic Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillators

Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery

Heat Activated Liposomal Doxorubicin and Radiofrequency Ablation in Treating Patients With Primary or Metastatic Liver Tumors

A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain

Barrett's Esophagus & Gastroesophageal Reflux Disease

Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry

Outcome of Different Ablation Strategies In Persistent and Long-Standing Persistent Atrial Fibrillation

Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers

Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure

Efficacy of Cooled and Monopolar Radiofrequency Ablation of the Geniculate Nerves for the Treatment of Chronic Osteoarthritic Knee Pain

Use of Cooled Radiofrequency for the Treatment of Hip Pain Associated With OA of the Hip Compared to Intra-articular Steroid Injections

Radiofrequency Ablation of Uterine Fibroids

A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esophagus

Fludeoxyglucose F 18-PET Imaging for Early Detection of Residual Disease in Patients Undergoing Radiofrequency Ablation of Liver Metastases From Colorectal Cancer

Radiofrequency Ablation in Treating Patients With Liver Cancer and Cirrhosis

Dual Epicardial Endocardial Persistent Atrial Fibrillation(AF) Study (Staged DEEP)

Radiofrequency Ablation of Atrial Fibrillation Under Apnea