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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:43 PM EDT

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Showing 433–456 of 2,205 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Reduced Activity Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Remote Mindfulness Training Following Early Life Adversity 2

NCT07085052
View directory record Official record
Conditions
Stress, Mindfulness, Early Life Adversity
Interventions
Mindfulness-Based Stress Reduction (MBSR)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 29 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Terminated Phase 3 Interventional Results available

This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure

NCT01035255
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction
Interventions
LCZ696 200 mg BID, Enalapril 10 mg BID
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
8,442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
155
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 129 more
Source: ClinicalTrials.gov public record
Updated Aug 15, 2016 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise-Induced Epigenetic Modifications in Obese Aging Women

NCT01977885
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
High Protein Diet, Exercise
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
50 Years to 64 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 25, 2015 · Synced Oct 20, 2026, 1:43 PM EDT
Not listed Not applicable Interventional

Fall Risk Reduction in Multiple Sclerosis (FIRMS)

NCT02314585
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Exercise, Education
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Oct 20, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation

NCT06395506
View directory record Official record
Conditions
Breast Cancer, Breast Cancer Female, Muscle Weakness
Interventions
Creatine
Dietary Supplement
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Minority Health Through Biofeedback and Stress Reduction

NCT07172152
View directory record Official record
Conditions
Cardiovascular Disease Risk Reduction, Chronic Stress, Anxiety, Emotional Regulation, Hypertension Prevention, Health Disparities
Interventions
HRV Biofeedback Training
Behavioral
Lead sponsor
Amelia Saul, PhD, CTRS, BCB
Other
Eligibility
18 Years to 35 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Manualized Assessment and Treatment Model of Challenging Behavior

NCT05928247
View directory record Official record
Conditions
Problem Behavior, Aggression, Self-Injury
Interventions
Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking, Research Units in Behavioral Intervention (RUBI) protocol
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
3 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Lifestyle Intervention for Healthy Change

NCT05956574
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Nutrigenomix, personalized dietary plan, Physical Activity, Behavioral counseling, Standard Dietary plan
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 40 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 2 Interventional Results available

Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis

NCT00424346
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Canakinumab, Placebo
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
12
States / cities
Anniston, Alabama • Birmingham, Alabama • Peoria, Arizona + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2014 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Intervention Targeting Medication Adherence and Methamphetamine Use in HIV Positive Men (ACE)

NCT01122186
View directory record Official record
Conditions
HIV Medication Adherence, Methamphetamine Use, Sexual Risk, Poly-substance Use, HIV Infections
Interventions
Motivational Interviewing + Cognitive Behavioral Skills Training, Education Attention Control
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years and older · Male only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study)

NCT00928005
View directory record Official record
Conditions
Overweight, Obesity, Type 2 Diabetes, Prediabetes
Interventions
Weight loss diet, Weight loss diet plus exercise
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
30 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 4, 2013 · Synced Oct 20, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional

Enhancing Language Function in Primary Progressive Aphasia

NCT04920318
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
tDCS + language therapy, sham TDCS + language therapy
Combination Product
Lead sponsor
University of Arizona
Other
Eligibility
45 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 20, 2026, 1:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TOTEM: Trial of TAP Block Effective Medications

NCT04382859
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Transversus abdominis plane (TAP) block with liposomal bupivacaine
Procedure
Lead sponsor
Western Michigan University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 27, 2020 · Synced Oct 20, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Metabolic Dysregulation in Dyads

NCT06117241
View directory record Official record
Conditions
Colorectal Cancer, Inflammation, Nutrition Related Cancer
Interventions
IMAGINE HEALTHY
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
9 Years to 55 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Peer-led EVERYbody Project

NCT04517942
View directory record Official record
Conditions
Body Image, Eating Disorder Symptom
Interventions
EVERYbody Project, Video + Expressive Writing
Behavioral · Other
Lead sponsor
Western Washington University
Other
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Bellingham, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2021 · Synced Oct 20, 2026, 1:43 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Dronabinol as an Adjunct for Reducing Pain

NCT06454669
View directory record Official record
Conditions
Low Back Pain, Chronic Pain, Back Injuries
Interventions
Dronabinol, Placebo
Drug
Lead sponsor
Christopher D. Verrico
Other
Eligibility
18 Years to 64 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

WHC+ (Women's Health CoOp PLUS)

NCT01497405
View directory record Official record
Conditions
HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse, Violence, Victimization
Interventions
Test, Treat, Retain(TTR) + Women's Health CoOp (WHC), Test, Treat, Retain(TTR) only
Behavioral · Biological
Lead sponsor
RTI International
Other
Eligibility
15 Years to 55 Years · Female only
Enrollment
641 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 2 Interventional

A Study to Evaluate ASP8232 in Reducing Central Retinal Thickness in Subjects With Diabetic Macular Edema (DME)

NCT02302079
View directory record Official record
Conditions
Diabetes Mellitus, Diabetic Macular Edema
Interventions
ASP8232, ranibizumab, Placebo, Sham intravitreal (IVT) injection
Drug · Other
Lead sponsor
Astellas Pharma Europe B.V.
Industry
Eligibility
18 Years to 85 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
21
States / cities
Phoenix, Arizona • Tucson, Arizona • Arcadia, California + 18 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Real-time Intervention for Suicide Risk Reduction

NCT05848089
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt
Interventions
Brief skills sessions plus EMI skills practice prompts, Ecological momentary assessment (EMA), Treatment as usual (TAU)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 20, 2026, 1:43 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Successful Aging and Enrichment (SAGE)

NCT05128396
View directory record Official record
Conditions
Cognitive Health, Healthy Aging
Interventions
Cognitive Stimulation, Mindfulness training, Physical Activity, Control Group
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 20, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional

Pharmacogenomic Informed Statin Prescribing

NCT06568601
View directory record Official record
Conditions
Hypercholesterolemia
Interventions
Pharmacogenetic and polygenic risk testing, Active control
Genetic · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 75 Years
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Indianapolis, Indiana • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Virtual Lifestyle Medicine Comparative Effectiveness Research

NCT03731481
View directory record Official record
Conditions
Chronic Disease, Obesity, Sleep Disorder, Depression
Interventions
Lifestyle Medicine
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 15, 2019 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 2 Interventional

Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans

NCT04360681
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Opioid-use Disorder
Interventions
Lofexidine, Placebo oral tablet
Drug
Lead sponsor
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Other
Eligibility
18 Years to 70 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Data2Action Oregon Project: Supporting Data-driven Decision-Making for Substance Use Services, Policy, and Overdose Prevention

NCT06852170
View directory record Official record
Conditions
Substance Abuse, Decision Making, Shared, Implementation Science, Decision Making, Organizations, Substance-related Disorders, Policy
Interventions
Co-Design Sessions (CDS), Data products
Other
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
341 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 20, 2026, 1:43 PM EDT