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ClinicalTrials.gov public records Last synced Nov 4, 2026, 12:37 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1729–1752 of 2,209 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Reduced Activity Clear all

Conditions: Type 2 Diabetes, Mental Health Issue, Quality of Life, Weight Loss
Interventions: CBT-based lifestyle intervention; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 35 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Left Ventricular Ejection Fraction, Heart Failure (HF), Left Bundle-Branch Block
Interventions: LB-CRT, BIV-CRT; Device
Lead sponsor: Inova Health Care Services; Other
Eligibility: Not listed
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Durham, North Carolina • Falls Church, Virginia

Conditions: Stress, Psychological, Sleep, Inflammation, Cardiovascular Diseases
Interventions: Mindfulness-Based Stress Reduction (MBSR); Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 87 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Menorrhagia
Interventions: Levonorgestrel IUS (Mirena, BAY86-5028), Medroxyprogesterone acetate; Drug
Lead sponsor: Bayer; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 37
States / cities: Tucson, Arizona • Beverly Hills, California • Carmichael, California + 32 more

Conditions: Obesity, Sedentary Lifestyle
Interventions: I-STAND, Healthy Living; Behavioral · Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 60 Years to 89 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Knee Osteoarthritis, Depression
Interventions: Aerobic exercise, Duloxetine; Behavioral · Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 40 Years and older
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tourette's Syndrome
Interventions: PF-03654746, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 55 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Manhasset, New York

Conditions: Parkinson Disease, Movement Disorders
Interventions: Libra Deep Brain Stimulation System; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2016
U.S. locations: 15
States / cities: Loma Linda, California • Gainesville, Florida • Miami, Florida + 11 more

Conditions: Dementia With Lewy Bodies, Parkinson Disease Dementia, Healthy Controls
Interventions: Syn-One skin biopsy, Multi modal MRI, Assessment of dynamic EEG features over 48-hour periods across all study aims, Plasma biomarkers, Galantamine HBr extended-release 8mg capsules (8mg ER).; Procedure · Diagnostic Test · Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 50 Years to 89 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Multiple Sclerosis, Fatigue
Interventions: 4-week Relaxation Training, 4-week Behavioral Activation, 4-week Cognitive Therapy; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Prostate Adenocarcinoma, PSA Failure, PSA Progression, Recurrent Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8, Stage IIC Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8
Interventions: Clinical Observation, Patient Observation, Questionnaire Administration, White Button Mushroom Extract; Other · Drug
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 18 Years and older · Male only
Enrollment: 133 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 7
States / cities: Duarte, California • Glendora, California • Irvine, California + 4 more

Conditions: Hypertension, Fall
Interventions: Tai Chi tailored for lowering blood pressure (PRESSURE), Tai Chi tailored for improving balance (BALANCE); Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 50 Years and older
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Bloomfield, Connecticut

Conditions: Obesity
Interventions: Adapted Dietary Guidelines, Adapted Physical Activity Guidelines; Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 35 Years to 64 Years
Enrollment: 129 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Overweight and Obesity, Overweight, Obesity
Interventions: Simple, Standard; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 2 Years to 55 Years
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Post Operative Pain
Interventions: SABER-Bupivacaine (Part 1), SABER-Bupivacaine (Part 2), Saline Placebo, Bupivacaine HCl; Drug
Lead sponsor: Durect; Industry
Eligibility: 18 Years and older
Enrollment: 399 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 21
States / cities: Florence, Alabama • Sheffield, Alabama • Arcadia, California + 13 more

Conditions: Alcoholism, Alcohol Abuse, Alcohol Dependence
Interventions: Dutasteride, sugar pill; Drug
Lead sponsor: UConn Health; Other
Eligibility: 18 Years to 70 Years · Male only
Enrollment: 189 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Depression, Anxiety, Stress
Interventions: Mindfulness-based Cognitive Therapy (MBCT), Mindfulness-based Stress Reduction (MBSR); Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 55 Years
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Overweight, Weight Loss
Interventions: mDiet; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 21 Years to 60 Years
Enrollment: 318 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Diabetes Mellitus, Diabetic Macular Edema
Interventions: ASP8232, ranibizumab, Placebo, Sham intravitreal (IVT) injection; Drug · Other
Lead sponsor: Astellas Pharma Europe B.V.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 21
States / cities: Phoenix, Arizona • Tucson, Arizona • Arcadia, California + 18 more

Conditions: Multiple Sclerosis, Neuropathic Pain
Interventions: Active tDCS using tDCS device, SHAM tDCS using tDCS device; Device
Lead sponsor: Thorsten Rudroff; Other
Eligibility: 18 Years to 65 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Failure to Launch, Anxiety Disorders, Hikikomori
Interventions: SPACE parental-guidance; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Breast Cancer Surgery
Interventions: Nipple Sparing Mastectomy (NSM), Skin-Sparing Mastectomy (SSM), Total (Simple) Mastectomy; Procedure
Lead sponsor: Sir Mortimer B. Davis - Jewish General Hospital; Other
Eligibility: 18 Years to 90 Years · Female only
Enrollment: 4,700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 5
States / cities: New Haven, Connecticut • Boston, Massachusetts • New York, New York + 2 more

Conditions: Myofascial Pain Syndrome
Interventions: Multiple Component Mobile-Aid Pain Reduction Intervention, Osteopathic Manipulation Treatment, Sham Osteopathic Manipulation; Behavioral · Other
Lead sponsor: Kailea Manning; Other
Eligibility: 18 Years to 64 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 2
States / cities: Auburn, Alabama

Conditions: Heart Failure
Interventions: Animal-assisted Therapy; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 80 Years
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Community-based CBT and T2D in Latino Population

REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)

Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers

Study in Women With Idiopathic Menorrhagia to Determine the Reduction in Menstrual Blood Loss (MBL) After Treatment With the Levonorgestrel-releasing Intrauterine System (IUS)

I-STAND R21: Reducing Sedentary Time in Older Adults

Exercise Plus Duloxetine for Knee Osteoarthritis

Study Evaluating The Safety And Efficacy Of PF-03654746 In Adult Subjects With Tourette's Syndrome

Deep Brain Stimulation to Treat Symptoms of Parkinson's Disease

Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia

Prospective Case Series to Refine Standalone Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue

White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA

Health Outcomes of Two Different Tai Chi Interventions

Steps Ahead, Adapting Physical Activity Guidelines for the Lower Mississippi Delta Population

Mobile Methods for Reducing Obesity Risk in Parents and Children

Trial of Extended Release Bupivacaine for Pain Relief After Surgery

Dutasteride Treatment for the Reduction of Heavy Drinking in Men

Mechanisms of Mindfulness-based Interventions

mDiet: A Text Message Intervention for Weight Loss

A Study to Evaluate ASP8232 in Reducing Central Retinal Thickness in Subjects With Diabetic Macular Edema (DME)

Transcranial Direct Current Stimulation to Lower Neuropathic Pain in People With Multiple Sclerosis

Parental Guidance for Failure to Launch.

Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer

A Multiple Component Mobile-aid Pain Reduction Intervention to Decrease Myofascial Pain

Animal-Assisted Therapy for Hospitalized Heart Failure Patients