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ClinicalTrials.gov public records Last synced Nov 9, 2026, 1:59 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1993–2016 of 2,211 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Reduced Activity Clear all

Conditions: Hypertension, Diabetes Mellitus, Type 2
Interventions: Ertugliflozin, Hydrochlorothiazide 12.5mg, Microneurography, SKNA recordings, Static Handgrip, Post-handgrip forearm vascular occlusion, Testing of the Arterial Baroreflex Function; Drug · Device · Other
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 35 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Diabetes, Dyslipidemia, Hypertension, Coronary Atherosclerosis
Interventions: Counseling, Interactive Education, Group Support, Pharmacologic case management; Behavioral · Procedure
Lead sponsor: Providence VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Type II Diabetes Mellitus
Interventions: RAS 130 with diet and exercise; Other
Lead sponsor: American Scitech International; Other
Eligibility: 30 Years to 60 Years
Enrollment: 460 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 3
States / cities: East Brunswick, New Jersey • New Brunswick, New Jersey • Perth Amboy, New Jersey

Conditions: Wet Macular Degeneration
Interventions: Aflibercept Ophthalmic, optovue angiovue; Drug · Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 50 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Nicotine Dependence
Interventions: Behavioral Counseling, Self-help control; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Traumatic Brain Injury
Interventions: GetUp&Go, GetUp&Go with 10-Week Delay; Behavioral
Lead sponsor: Albert Einstein Healthcare Network; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Elkins Park, Pennsylvania

Conditions: Smoking Cessation
Interventions: RITCh Treatment, Standard Treatment; Behavioral
Lead sponsor: The City College of New York; Other
Eligibility: 18 Years and older
Enrollment: 256 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Physical Activity, Blood Pressure, Physical Functioning, Quality of Life, Sedentary
Interventions: Physical Activity, Group educational sessions, Phone counseling call, Peer Mentoring, Policy Change, Support, Tailored environmental resources, Health check phone call, Pedometer; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 65 Years and older
Enrollment: 307 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Overweight, Obesity
Interventions: Weight loss; Behavioral
Lead sponsor: University of North Carolina, Greensboro; Other
Eligibility: 18 Years and older · Female only
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Greensboro, North Carolina

Conditions: Preterm Birth
Interventions: Docosahexaenoic acid - 800mg/day, Docosahexaenoic acid - 200mg/day, Placebo; Drug · Other
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1,100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 3
States / cities: Kansas City, Kansas • Cincinnati, Ohio • Columbus, Ohio

Conditions: Hypertension
Interventions: GOALS, Minding GOALS; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 21 Years to 79 Years
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hip Fracture
Interventions: Nutrition, PUSH, PULSE; Dietary Supplement · Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 60 Years and older
Enrollment: 210 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 4
States / cities: Farmington, Connecticut • Baltimore, Maryland • Lebanon, New Hampshire + 1 more

Conditions: Psychosis
Interventions: Cognitive Remediation, Active Control; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 15 Years to 100 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Polycystic Ovary Syndrome, Overweight, Obesity, Stress, Physiological, Stress, Psychological
Interventions: Stress reduction, Stress reduction with Health education; Behavioral
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Gaucher Disease
Interventions: Digital Engagement Application (GD App), No Intervention; Other
Lead sponsor: Takeda; Industry
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Fairfax, Virginia

Conditions: ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL Sprain, ACL Tear
Interventions: CBPT-ACLR, Education; Behavioral · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 14 Years to 35 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: Garfield Heights, Ohio • Nashville, Tennessee

Conditions: Acute Heart Failure
Interventions: sacubitril/valsartan (LCZ696), Enalapril, sacubitril/valsartan (LCZ696) matching placebo, enalapril matching placebo; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 887 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 123
States / cities: Birmingham, Alabama • Fort Smith, Arkansas • Little Rock, Arkansas + 105 more

Conditions: Chronic Spine Pain, Fibromyalgia
Interventions: Web-based Cognitive Behavioral Therapy (e-CBT) Self-Management, Promoting Resilience through Innovative Self-Management; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 35 Years to 65 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Alcohol Use Disorder (AUD), Nicotine Use Disorder
Interventions: Contingency Management, Non-contingent control; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 18 Years and older
Enrollment: 205 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Obesity
Interventions: Egg Breakfast (EB), Cereal Breakfast (CB), Weight Loss Counseling, Weight Loss Diet; Behavioral
Lead sponsor: Texas Tech University; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Lubbock, Texas

Conditions: Ischemic Heart Disease, Hopelessness, Physical Activity, Motivation, Social Support, Covid19
Interventions: Motivational social support from nurse, Motivational social support from nurse with additional support from significant other, Attention control; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: Depression
Interventions: Citalopram, Methylphenidate (MPH), Placebo; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 60 Years and older
Enrollment: 181 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Opioid Use Disorder, Sleep Disturbance
Interventions: Post-Illumination Pupillary Response (PIPR), Polysomnography, Multiple Sleep Latency Test, Ecological Momentary Assessments, Actigraphy, DLMO, Melatonin Suppression Test; Other · Behavioral · Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 80 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Teen Pregnancy Prevention
Interventions: Teens Exploring and Managing Prevention Options (TEMPO); Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 13 Years to 19 Years
Enrollment: 447 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Search by objective public record fields.

Ertugliflozin Versus Hydrochlorothiazide in Reducing Sympathetic Neural Overactivity in Patients With Hypertension and Recently-diagnosed Type 2 Diabetes.

Strategies to Maintain Cardiac Risk Control After Discharge From Cardiovascular Risk Reduction Clinic

Evaluate the Side Effects and Benefits of RAS 130 With or Without Diet and Exercise in Type II Diabetes Mellitus

The IAI-OCTA Study; a Study of OCT-Angiography Analysis Efficacy

Counseling to Reduce Children's SHS Exposure: A Trial With Maternal Smokers

GetUp&Go: A Randomized Controlled Trial of an Intervention to Enhance Physical Activity After TBI

RITCH: Reducing Disparities in Tobacco Cessation Outcomes

Multilevel Intervention for Physical Activity in Retirement Communities

Get Active and Eat Right: Moms at Work

Assessment of DHA On Reducing Early Preterm Birth

Minding GOALS: An Internet-Assisted Mind-Body-Behavior Program for Blood Pressure Control

Improving Community Ambulation After Hip Fracture

Mechanisms of Cognitive Change

Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)

A Study of Enzyme Replacement Therapy (VPRIV) in People With Type 1 Gaucher Disease Who Were Previously Treated With Substrate Reduction Therapy

Improving ACL Reconstruction Outcomes: CBPT

Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-proBNP in Patients Stabilized From an Acute Heart Failure Episode.

Resilience Skills Self-Management for Chronic Pain.

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking

Breakfast Intake and Satiety Hormones

Reducing Hopelessness Through Improved Physical Activity in Adults With Heart Disease: With COVID-19 Considerations

Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With Depression

Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

Brief Intervention for Teen Pregnancy Prevention