- Conditions
- Keratitis, Corneal Ulcer
- Interventions
- Standard of Care Therapy + CXL + Riboflavin 0.23% L Solution, Standard of Care Therapy + Sham CXL + Artificial Tears
- Combination Product · Other
- Lead sponsor
- Peschke GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 468 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 12
- States / cities
- Littleton, Colorado • Fort Myers, Florida • Tampa, Florida + 9 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 29
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Keratoconus
- Interventions
- PXL Platinum 330 system
- Device
- Lead sponsor
- Cohen Laser and Vision Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2034
- U.S. locations
- 1
- States / cities
- Boca Raton, Florida
- Conditions
- Progressive Keratoconus
- Interventions
- NXL Energy 1, NXL Energy 2, NXL Energy 3, Sham Treatment
- Combination Product
- Lead sponsor
- Glaukos Corporation
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 3
- States / cities
- Dothan, Alabama • Teaneck, New Jersey • Westerville, Ohio
- Conditions
- Keratoconus, Ectasia
- Interventions
- Riboflavin
- Drug
- Lead sponsor
- Yaron S. Rabinowitz M.D.
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2021
- U.S. locations
- 1
- States / cities
- Beverly Hills, California
- Conditions
- Keratoconus, Post-Refractive Ectasia
- Interventions
- Riboflavin, UVX light
- Drug · Device
- Lead sponsor
- Price Vision Group
- Industry
- Eligibility
- 10 Years and older
- Enrollment
- 510 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2017
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Keratitis Bacterial
- Interventions
- Moxifloxacin Ophthalmic, Difluprednate Ophthalmic, Riboflavin Ophthalmic, Topical Placebo
- Drug · Other
- Lead sponsor
- Thomas M. Lietman
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 280 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 2
- States / cities
- San Francisco, California • Miami, Florida
- Conditions
- Keratoconus, Corneal Ectasia
- Interventions
- Riboflavin 0.1% ophthalmic solution, CCL-VARIO UV lamp, CCL-VARIO at 18 mW/cm2
- Drug · Device
- Lead sponsor
- Robert Mack, M.D.
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2013
- U.S. locations
- 1
- States / cities
- Hoffman Estates, Illinois
- Conditions
- Keratoconus, Ectasia of Cornea, Pellucid Marginal Corneal Degeneration, Forme Fruste Keratoconus (FFK)
- Interventions
- Epi-ON corneal cross-linking
- Combination Product
- Lead sponsor
- Woolfson Eye Institute
- Other
- Eligibility
- 8 Years and older
- Enrollment
- 485 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 12
- States / cities
- Atlanta, Georgia • Canton, Georgia • Cumming, Georgia + 8 more
- Conditions
- Keratoconus
- Interventions
- Riboflavin-5-phosphate, Sham cross-linking
- Drug
- Lead sponsor
- University at Buffalo
- Other
- Eligibility
- 16 Years to 35 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2011
- U.S. locations
- 2
- States / cities
- Amherst, New York • Buffalo, New York
- Conditions
- Keratoconus, Corneal Ectasia
- Interventions
- Riboflavin
- Drug
- Lead sponsor
- Cornea and Laser Eye Institute
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2025
- U.S. locations
- 1
- States / cities
- Teaneck, New Jersey
- Conditions
- Keratoconus
- Interventions
- Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% with UV light, Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% without UV light
- Drug
- Lead sponsor
- Joseph B. Ciolino, MD
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 216 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Hyperopia, Hyperopic Astigmatism
- Interventions
- riboflavin ophthalmic solution, 0% dextran, UVA Irradiation (30 mW/cm2 for 2 minutes continuous UVA), UVA Irradiation (30 mW/cm2 for 3 minutes pulsed UVA with an on/off cycle of 2 seconds UVA on/1 second UVA off), Laser-assisted in situ keratomileusis
- Drug · Device · Procedure
- Lead sponsor
- Glaukos Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 5
- States / cities
- San Diego, California • Waltham, Massachusetts • Teaneck, New Jersey + 2 more
- Conditions
- Keratoconus, Corneal Ectasia
- Interventions
- Riboflavin
- Drug
- Lead sponsor
- Cornea and Laser Eye Institute
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Teaneck, New Jersey
- Conditions
- Keratoconus, Ectasia Corneal
- Interventions
- Riboflavin 0.1%
- Combination Product
- Lead sponsor
- Price Vision Group
- Industry
- Eligibility
- 10 Years and older
- Enrollment
- 510 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Keratoconus, Corneal Ectasia
- Interventions
- riboflavin ophthalmic solution
- Drug
- Lead sponsor
- Cornea and Laser Eye Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Teaneck, New Jersey
- Conditions
- Keratoconus
- Interventions
- riboflavin solution, placebo solution, KXL System
- Drug · Device
- Lead sponsor
- Glaukos Corporation
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 92 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 11
- States / cities
- Irvine, California • San Diego, California • Indianapolis, Indiana + 8 more
- Conditions
- Progressive Keratoconus, Corneal Ectasia
- Interventions
- Riboflavin, Placebo
- Drug
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2010
- U.S. locations
- 2
- States / cities
- Columbus, Ohio • Dublin, Ohio
- Conditions
- Ectasia
- Interventions
- riboflavin ophthalmic solution, UVA Irradiation
- Drug · Device
- Lead sponsor
- Glaukos Corporation
- Industry
- Eligibility
- 14 Years and older
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 10
- States / cities
- La Jolla, California • San Diego, California • Miami, Florida + 7 more
- Conditions
- Keratoconus, Corneal Ectasia
- Interventions
- Riboflavin
- Drug
- Lead sponsor
- Cornea and Laser Eye Institute
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Teaneck, New Jersey
- Conditions
- Keratoconus
- Interventions
- Riboflavin drops
- Drug
- Lead sponsor
- Nvision Laser Eye Centers
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 320 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 11
- States / cities
- Camarillo, California • Citrus Heights, California • Fullerton, California + 8 more
- Conditions
- Keratoconus, Corneal Ectasia
- Interventions
- Riboflavin
- Drug
- Lead sponsor
- Cornea and Laser Eye Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2025
- U.S. locations
- 1
- States / cities
- Teaneck, New Jersey
- Conditions
- Keratoconus, Ectasia
- Interventions
- UVA Light with irradiance exposure of 9 mW/cm2, Riboflavin 0.1% ophthalmic solution
- Device · Drug
- Lead sponsor
- Stephen Trokel
- Other
- Eligibility
- 16 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Progressive Keratoconus
- Interventions
- riboflavin ophthalmic solution, UVA Irradiation
- Drug · Device
- Lead sponsor
- Glaukos Corporation
- Industry
- Eligibility
- 14 Years and older
- Enrollment
- 147 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 10
- States / cities
- La Jolla, California • San Diego, California • Miami, Florida + 7 more
- Conditions
- Keratoconus, Ectasia
- Interventions
- Ricrolin+, VEGA UV-A system
- Drug · Device
- Lead sponsor
- Center for Sight, Sacramento, CA
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 550 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Sacramento, California