- Conditions
- Colorectal Cancer (Diagnosis), Adenoma
- Interventions
- S-Adenosylmethionine (SAMe)
- Drug
- Lead sponsor
- Jun Gong, MD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Los Angeles, California
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Showing 25–33
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Colorectal Cancer, Liver Metastases, Liver Metastasis Colon Cancer, Liver Injury, Sinusoidal Obstruction Syndrome, 5-Fluorouracil Toxicity, Liver Toxicity, Chemically-Induced
- Interventions
- Standard of care oxaliplatin-based chemotherapy, S-adenosylmethionine (SAMe) supplement, Surgery
- Radiation · Dietary Supplement · Procedure
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 2
- States / cities
- Los Angeles, California
- Conditions
- Tobacco Use
- Interventions
- Standard intervention (counseling + self-help written materials), Enhanced Intervention (same as standard treatment plus 10-15 min of counseling and a culturally tailored video)
- Behavioral
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Adult Primary Liver Cancer, Hepatitis C Infection
- Interventions
- S-adenosyl-L-methionine disulfate p-toluene-sulfonate, placebo, laboratory biomarker analysis, immunoenzyme technique, high performance liquid chromatography
- Drug · Other
- Lead sponsor
- Chao Family Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2013
- U.S. locations
- 5
- States / cities
- Tucson, Arizona • Long Beach, California • Los Angeles, California + 2 more
- Conditions
- Osteoarthritis Hand
- Interventions
- S-Adenosyl-L-Methionine (Sam-E), Placebo
- Drug
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Mild Cognitive Impairment
- Interventions
- Memory XL, placebo
- Drug
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 55 Years to 85 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 2
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Major Depressive Disorder (MDD)
- Interventions
- MSI-195, Placebo
- Drug
- Lead sponsor
- MSI Methylation Sciences, Inc.
- Industry
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 376 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 35
- States / cities
- Birmingham, Alabama • Encino, California • Escondido, California + 30 more
- Conditions
- Stroke
- Interventions
- FAST alone, FAST+SAM, SAM alone
- Behavioral
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2023
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Sleep Disturbances
- Interventions
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Dietary Supplement
- Lead sponsor
- Bonafide Health
- Industry
- Eligibility
- 40 Years to 65 Years · Female only
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Harrison, New York