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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:44 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 87 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: SBIRT+ Clear all

Conditions: Alcohol Drinking
Interventions: SSL Implementation Strategy; Other
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 12 Years to 17 Years
Enrollment: 430 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Substance Use
Interventions: Not listed
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 17 Years
Enrollment: 810 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: HIV (Human Immunodeficiency Virus), Substance Abuse Disorder
Interventions: Community Coalition CLS Workgroup/Network of Providers, Tech-mediated Training and Service Delivery, Multidisciplinary Implementation Team with Champion, Tech-mediated Peer Navigation Enhanced Case management (NCM); Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Kingston, New York

Conditions: Opioid Use Disorder
Interventions: OARSCM Software Application, MyMAT Software Application; Other
Lead sponsor: Q2i, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Adolescent Alcohol Use
Interventions: Brief Motivational Interviewing-based Alcohol Intervention, Smartphone App-delivered Mindfulness Training; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 12 Years to 17 Years
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 13
States / cities: Baltimore, Maryland • Belcamp, Maryland • Bowie, Maryland + 6 more

Conditions: Drug Abuse, HIV Risk Behavior
Interventions: Computerized brief intervention, Counselor delivered brief intervention; Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Substance Use, HIV Infections
Interventions: SBIRT, Control Group; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 100 Years
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Alcohol Use
Interventions: Smartphone brief intervention (SP-BI), Enhanced Usual Care (EUC); Behavioral · Other
Lead sponsor: Keming Gao; Other
Eligibility: Not listed
Enrollment: 850 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 2
States / cities: Cleveland, Ohio • Toledo, Ohio

Conditions: Alcohol-Related Disorders, Substance-Related Disorders, Mental Health, Reproductive Health, Sexual Health, Sexually Transmitted Diseases, Contraception, Maternal Health, Pregnancy, Women's Health
Interventions: Screening, Brief Intervention, and Referral to Treatment (SBIRT); Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 4
States / cities: Boston, Massachusetts • Marlborough, Massachusetts • Springfield, Massachusetts + 1 more

Conditions: Substance-related Disorders, Depression, High-risk Sex
Interventions: iSBIRT, iSBIRT/TE; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Smoking, Drinking
Interventions: Combined BNI; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Opioid Misuse, Opioid-Related Disorders, Pharmacist-Patient Relations
Interventions: Patient Navigation, Standard Medication Counseling (SMC); Behavioral · Other
Lead sponsor: Jerry Cochran; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Unhealthy Alcohol Use, Alcohol Use Disorders
Interventions: Not listed
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 100 Years · Male only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Alcohol-induced Disorders, Drug Users, Tobacco Use Disorder
Interventions: The brief interventions are delivered by behavioral health counselors (Specialist), The brief interventions are delivered by the primary care provider (Generalist); Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years to 99 Years
Enrollment: 98 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Prenatal Alcohol Exposure, Prenatal Tobacco Exposure, Prenatal Marijuana Exposure
Interventions: Computer tablet-delivered C4H, Person-delivered C4H, Brief Advice; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 219 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Smoking
Interventions: CATI Tool; Behavioral
Lead sponsor: HealthPartners Institute; Other
Eligibility: 18 Years to 100 Years
Enrollment: 548 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Bloomington, Minnesota

Conditions: Alcohol Use Disorder
Interventions: Naltrexone Pill, Naltrexone Injection, Brief Negotiation Interview, Gabapentin Pill; Drug · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Unhealthy Drinking, Alcohol Dependence
Interventions: Training & Tech Support for Delivery of Alcohol Screening, Brief Intervention, and Referral To Treatment; Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 639,613 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2018
U.S. locations: 1
States / cities: Oakland, California

Conditions: Substance Abuse
Interventions: Personalized feedback report, Personalized feedback report plus education; Behavioral
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 105 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Smoking Cessation
Interventions: SBIRT, HHC; Behavioral
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Not listed
Enrollment: 770 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Drug Abuse
Interventions: screening, assessment, referral, Brief intervention, booster sessions; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 1,285 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 7
States / cities: Miami, Florida • Boston, Massachusetts • Albuquerque, New Mexico + 4 more

Conditions: HIV Infections, Substance Use Disorders
Interventions: PrEPsteps, Digital pill, Truvada; Behavioral · Device · Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older · Male only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Boylston, Massachusetts

Conditions: Diabetes Mellitus, Type 2, Substance-related Disorders
Interventions: Referral to Treatment, Brief Intervention; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Alcohol Abuse, Tobacco Dependence, Substance Abuse
Interventions: cSBI-M; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 18 Years to 25 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Implementing Alcohol Misuse SBIRT in a National Cohort of Pediatric Trauma Centers

Adolescent SCreening To Help Eliminate Misuse

TechMPower: Advancing HIV/SUD Care and Service Delivery for People in Re-entry

Reward-based Technology to Improve OUD Treatment

Brief Motivational Interviewing +/- Mindfulness Training for Adolescent Alcohol Use in Pediatric Primary Care

Screening Brief Intervention Referral to Treatment (SBIRT) in New Mexico

Screening, Brief Intervention, and Referral to Treatment for Offenders

Project Guard: Reducing Alcohol Misuse/Abuse in the National Guard

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

Primary Care iSBIRT to Reduce Serious Teen Health Risks

Combination SBIRT for Emergency Department Patients Who Drink and Smoke

Healthy Opioid Prescription Engagement

Tailoring Screening, Brief Intervention, and Referral to Treatment for Medical ICU Survivors

SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers

Choices4Health: Intervention to Prevent Substance-exposed Pregnancy

Computer-Assisted Tobacco Interventions in Dental Offices

Emergency Department-Initiated Medications for Alcohol Use Disorder

Alcohol Drinking as a Vital Sign

Impact of Personalized Feedback Alone on Substance Use Behaviors

An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients

Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments

Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps)

Screening, Brief Intervention, and Referral to Treatment in Primary Care

cSBI-M for Young Military Personnel