Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 6, 2026, 4:16 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 589 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: SIGNAL Clear all

Conditions: Anesthesia
Interventions: BIS Complete Monitoring System; Device
Lead sponsor: Medtronic - MITG; Industry
Eligibility: 4 Years to 18 Years
Enrollment: 209 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 8
States / cities: Aurora, Colorado • Chicago, Illinois • Minneapolis, Minnesota + 5 more

Conditions: Laryngeal Dystonia
Interventions: neurofeedback brain-computer interface (BCI); Device
Lead sponsor: Kristina Simonyan; Other
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Normal Eyes
Interventions: OCT imaging; Device
Lead sponsor: Heidelberg Engineering GmbH; Industry
Eligibility: 22 Years and older
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Franklin, Massachusetts

Conditions: Chronic Pancreatitis, Chronic Pain
Interventions: Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3; Diagnostic Test
Lead sponsor: Anna Evans Phillips; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2031
U.S. locations: 2
States / cities: Baltimore, Maryland • Pittsburgh, Pennsylvania

Conditions: Advanced Solid Tumor, Metastatic Solid Tumor, Urothelial Cancer, Poorly Differentiated Neuroendocrine Carcinomas, Homologous Recombination Deficient-Positive Malignancies Agnostic
Interventions: Lurbinectedin; Drug
Lead sponsor: Jazz Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 17
States / cities: Stanford, California • Norwich, Connecticut • Fort Myers, Florida + 14 more

Conditions: Metastatic Melanoma, Metastasis to Brain
Interventions: Nivolumab, Ipilimumab, Nivolumab + Relatlimab, Standard of Care Craniotomy; Drug · Procedure
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: Tampa, Florida • Houston, Texas

Conditions: Hearing Loss
Interventions: Hearing Aids; Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Evanston, Illinois

Conditions: Vision
Interventions: psychophysics of sequential biases (no drug or patient work); Behavioral
Lead sponsor: University of California, Berkeley; Other
Eligibility: 18 Years and older
Enrollment: 10,120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2032
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Overweight and Obesity
Interventions: Kurbo Only, Kurbo + PolyRules!; Behavioral
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 7 Years to 13 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Medication Adherence
Interventions: Vitality GlowCaps; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smoke Inhalation Injury, Burns
Interventions: Smoke Alarm Stimuli; Other
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 5 Years to 84 Years
Enrollment: 834 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2018
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Major Depressive Disorder
Interventions: Auricular Acupuncture, Sham Auricular Acupuncture + Lexapro; Device · Drug
Lead sponsor: Florida Gulf Coast University; Other
Eligibility: 18 Years to 24 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Fort Myers, Florida

Conditions: Alcohol Use Disorder
Interventions: Cervical transcutaneous vagus nerve stimulation (active comparator), Cervical transcutaneous vagus nerve stimulation (sham comparator); Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: San Diego, California

Conditions: Chronic Pain
Interventions: Intraoperative Parameter Testing, Proprioception Testing During Stimulation, Gait Analysis During Stimulation; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Stroke
Interventions: measuring cognitive flexibility including working memory and set-switching; Behavioral
Lead sponsor: Kai Hwang; Other
Eligibility: 18 Years and older
Enrollment: 184 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: 2019 Novel Coronavirus Disease, 2019 Novel Coronavirus Infection, 2019-nCoV Disease, COVID-19 Pandemic, COVID-19 Virus Disease, COVID-19 Virus Infection, Coronavirus Disease 2019, Coronavirus Disease-19, SARS-CoV-2 Infection
Interventions: Diagnostic Test: Diagnostic Software as Medical Device; Device
Lead sponsor: AudibleHealth AI, Inc.; Industry
Eligibility: 18 Years to 100 Years
Enrollment: 514 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Sunrise, Florida

Conditions: Treatment Resistant Depression
Interventions: Discontinuation of serotonergic antidepressants, Continuation of serotonergic medications; Other
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years to 70 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Advanced Solid Tumor, Gynecologic Cancer, Breast Cancer, Colorectal Cancer, Lung Adenocarcinoma, Renal Cell Carcinoma, Triple Negative Breast Cancer, Hormone Receptor/Growth Factor Receptor-Negative Breast Cancer, Ovarian Cancer
Interventions: PY314, Combination Therapy: PY314 + Pembrolizumab; Drug
Lead sponsor: Ikena Oncology; Industry
Eligibility: 18 Years and older
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 23
States / cities: Phoenix, Arizona • Scottsdale, Arizona • Duarte, California + 18 more

Conditions: Inflammatory Bowel Diseases
Interventions: ECG recording, inflammatory cytokines, microbiota, ulcerative colitis disease activity index; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Major Depressive Disorder
Interventions: FMRI with sham controlled feedback, FMRI with real time feedback; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 55 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Chronic Post-surgical Pain
Interventions: Acceptance and Commitment Therapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 12 Years and older
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tourette Syndrome in Adolescence
Interventions: Neurofeedback from the SMA, Neurofeedback from control region; Other
Lead sponsor: Yale University; Other
Eligibility: 10 Years to 16 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Community Mobility of Older Adults, Locomotor Adaptability, Gait Automaticity
Interventions: Split-belt walking, Multiple transitions between split-belt and tied-belt walking; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 19 Years and older
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Asthma
Interventions: Resolve Stimulator and Proximity Lead; Device
Lead sponsor: ElectroCore INC; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 6
States / cities: Chicago, Illinois • Detroit, Michigan • Royal Oak, Michigan + 3 more

Search by objective public record fields.

Bispectral Index and End-Tidal Anesthetic Gas Concentration in Pediatric Patients

Brain-Computer Interfaces in Laryngeal Dystonia

Evaluation of Heidelberg Engineering SPECTRALIS OCT Signal to Noise Ratio Effect on Parameter Measurements

QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid Tumors

Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases

Individually-guided Hearing Aid Fitting

Isolating and Mitigating Sequentially Dependent Perceptual Errors in Clinical Visual Search

Inhibitory Control and Pediatric Weight Management

Medication Adherence in Kidney Transplant Recipients Using Automated Reminders and Provider Notification

Critical Smoke Alarm Characteristics to Awaken Children From Stage 4 Sleep

Adjunctive Treatment of Major Depression Utilizing Auricular Acupuncture

Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder

Effect of Epidural Stimulation on Muscle Activation and Sensory Perception

Cognitive Control Functions of the Human Thalamus

Evaluation of the AudibleHealth Dx AI/ML-Based Dx SaMD Using FCV-SDS in the Diagnosis of COVID-19 Illness: Clinical Validation

Antidepressant Discontinuation in Treatment Resistant Depression

A Study of PY314 in Subjects With Advanced Solid Tumors

Autonomic and Cytokines Profiles of Patients With Ulcerative Proctitis

Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback

Psychophysical and Neural Mechanisms Contributing to Chronic Post-Surgical Pain in Adolescents and Adults

Neurofeedback From the Supplementary Motor Area for Tourette Syndrome

Increasing Gait Automaticity in Older Adults by Exploiting Locomotor Adaptation

Neurostimulation for the Relief of Acute Bronchoconstriction