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ClinicalTrials.gov public records Last synced Oct 28, 2026, 2:14 AM EDT

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Showing 25–48 of 71 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: SMI Clear all
Completed Not applicable Interventional Results available

The Use of Skills Training to Augment Compensated Work Therapy (CWT)/VI for Veterans With SMI

NCT00272168
View directory record Official record
Conditions
Mental Illness, Schizophrenia
Interventions
Maryland Program for Vocational Effectiveness, Supportive Treatment for SMI
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2016 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional Results available

A Transdiagnostic Sleep and Circadian Treatment to Improve Community SMI Outcomes

NCT02469233
View directory record Official record
Conditions
Mental Disorders
Interventions
Transdiagnostic Intervention for Sleep and Circadian Dysfunction
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Appeal and Impact of E-cigarettes in Smokers With SMI

NCT03050853
View directory record Official record
Conditions
Tobacco Dependence, Schizophrenia, Bipolar Disorder, Schizoaffective Disorder
Interventions
E-cigarette
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Louisville, Kentucky • Lawrence, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 28, 2026, 2:14 AM EDT
Recruiting Not applicable Interventional

Peer Facilitated Waitlist Controlled Transportation Study

NCT06370767
View directory record Official record
Conditions
Serious Mental Illness
Interventions
Bike-Share Travel Training, Public Transportation Travel Training
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 1, 2024 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness

NCT05725785
View directory record Official record
Conditions
Schizophrenia, Bipolar Disorder, Major Depressive Disorder, Schizo Affective Disorder
Interventions
FOCUS participants
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
3
States / cities
St Louis, Missouri • Dover, New Hampshire • Manchester, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Phase 4 Interventional

Injectable Naltrexone Treatment of Alcohol Dependence in Serious Mental Illness (SMI)

NCT00453609
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Alcohol Dependence
Interventions
long-lasting injectable naltrexone
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 69 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
3
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2008 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional Results available

Improving Outcomes for Individuals With Serious Mental Illness and Diabetes

NCT01410357
View directory record Official record
Conditions
Diabetes Mellitus, Bipolar Disorder, Depression, Psychotic Disorders, Schizophrenia
Interventions
Targeted Training in Illness Management (TTIM)
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Oct 28, 2026, 2:14 AM EDT
Not yet recruiting Not applicable Interventional

Testing a Peer-Support Group for Veterans Who Hear Voices

NCT07555275
View directory record Official record
Conditions
Psychotic Disorders, Hallucinations, Auditory, Social Isolation
Interventions
Veteran Voices and Visions (VVV), Wellness Recovery Action Planning (WRAP)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
2
States / cities
West Los Angeles, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 28, 2026, 2:14 AM EDT
Recruiting Not applicable Interventional

CBT-CP for Veterans With SMI

NCT06758414
View directory record Official record
Conditions
Chronic Pain, Schizophrenia, Psychotic Disorders, Bipolar Disorder, Affective Disorders, Psychotic
Interventions
Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Health & Wellness (H&W)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional Results available

A New Paradigm for Illness Monitoring and Relapse Prevention in Schizophrenia

NCT01952041
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Device: Smartphone, Treatment as usual
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2019 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Phase 2 Interventional Results available

Reducing Internalized Stigma in People With Serious Mental Illness

NCT01259427
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depression With Psychotic Features
Interventions
Ending Self Stigma (ESS), Health and Wellness Group
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Perry Point, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 8, 2016 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Creating Welcoming Faith Communities for People With Serious Mental Illnesses

NCT06336980
View directory record Official record
Conditions
Other
Interventions
Increasing Inclusionary Practices in Faith Communities
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional Results available

Web-Based Delivery of MOVE! to Veterans With Serious Mental Illness (SMI)

NCT00983476
View directory record Official record
Conditions
Psychotic Disorders, Obesity, Health Behaviors
Interventions
in-person MOVE! SMI, web-based MOVE! SMI
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional Results available

Project Bridge: Peer Health Navigator Intervention

NCT02022462
View directory record Official record
Conditions
Schizophrenia, Depression, Medical Disorders, Serious Mental Illness
Interventions
Health Navigation
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 65 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Santa Fe Springs, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional

Life Goals Behavioral Change to Improve Outcomes for Veterans With Serious Mental Illness

NCT01244854
View directory record Official record
Conditions
Bipolar Disorder, Schizophrenia, Major Depressive Disorder, Chronic Affective Disorders, Cardiovascular Disease Risk
Interventions
Life Goals Collaborative Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 6, 2017 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional

Evaluation of mHealth for Serious Mental Illness

NCT04068467
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Major Depressive Disorder, Bipolar Disorder
Interventions
Smartphone App, Waitlist Control
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
315 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 11, 2021 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional

Evaluation of the In SHAPE Fitness Intervention for Adults With Serious Mental Illness

NCT02334228
View directory record Official record
Conditions
Schizophrenia, Bipolar Disorder, Schizoaffective Disorder, Major Depressive Disorder
Interventions
In SHAPE Lifestyles, Health Club Membership and Education
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
21 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 8, 2015 · Synced Oct 28, 2026, 2:14 AM EDT
Enrolling by invitation Not applicable Interventional

Mindfulness-Based Therapy for Serious Mental Illness

NCT06880796
View directory record Official record
Conditions
Serious Mental Illness, Schizophrenia, Major Depressive Disorder, Bipolar Disorder
Interventions
Mindfulness-based therapy, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional

An Integrated Approach to Smoking Cessation in Severe Mental Illness (SMI)

NCT00690131
View directory record Official record
Conditions
Smoking Cessation
Interventions
BTSCS
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 75 Years
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
3
States / cities
Baltimore, Maryland • Timonium, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional

Self-Management Training and Automated Telehealth to Improve SMI Health Outcomes

NCT02188732
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Depression
Interventions
CBHH+AT, CBHH+SMT, CBHH
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 27, 2021 · Synced Oct 28, 2026, 2:14 AM EDT
Recruiting Not applicable Interventional

Abriendo Caminos: Engaging Latinos

NCT07529509
View directory record Official record
Conditions
Serious Mental Illness
Interventions
Culturally responsive motivational interviewing
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 28, 2026, 2:14 AM EDT
Completed Not applicable Interventional

Health Care Management and Rehabilitation Skills Training for Treating Serious Mental Illness in Older People

NCT00169052
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depression
Interventions
Health Care Management and Supported Rehabilitation
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
50 Years and older · Female only
Enrollment
180 participants
Timeline
2001 – 2006
U.S. locations
3
States / cities
Boston, Massachusetts • Nashua, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 10, 2013 · Synced Oct 28, 2026, 2:14 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Intervention to Reduce Serious Mental Illness and Suicide Stigma Among Medical Students

NCT05325320
View directory record Official record
Conditions
Stigmatization, Clinical Competence
Interventions
SMI/SIA Stigma Reduction Intervention, Disaster Preparedness Course
Behavioral · Other
Lead sponsor
Ponce Medical School Foundation, Inc.
Industry
Eligibility
21 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 28, 2026, 2:14 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Getting to Zero Among HHI MSM in the American South

NCT05075967
View directory record Official record
Conditions
HIV Infections
Interventions
Health Access Coalitions, Social Media, Peer Support, Promoting Human Autonomy Support & Empathy (PHASE)
Behavioral
Lead sponsor
HIV Prevention Trials Network
Network
Eligibility
15 Years and older · Male only
Enrollment
2,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 28, 2026, 2:14 AM EDT