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ClinicalTrials.gov public records Last synced Oct 19, 2026, 11:24 PM EDT

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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional

DMHI for At-Risk College Students

NCT06608498
Conditions
Prodromal Symptoms, Psychosis
Interventions
SPARK Coping
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

The REMIND Study- SPARK Neuro Software Study

NCT05406778
Conditions
Alzheimer Disease, Cognitive Impairment
Interventions
SPARK Test
Device
Lead sponsor
Spark Neuro Inc.
Industry
Eligibility
55 Years to 85 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
7
States / cities
Loma Linda, California • Englewood, Colorado • Ocala, Florida + 4 more
Not yet recruiting Not applicable Interventional

NST-SPARK Open-Label Phase 1 STTR (IGNITE)

NCT07593456
Conditions
Schizophrenia / Schizoaffective Disorder
Interventions
NST-SPARK
Device
Lead sponsor
North Shore Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
2
States / cities
Glen Oaks, New York • Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19

NCT04524598
Conditions
Depression
Interventions
Limbix Spark, Psychoeducation
Device · Other
Lead sponsor
Limbix Health, Inc.
Industry
Eligibility
13 Years to 21 Years
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Conditions
Opioid Withdrawal, Analgesia
Interventions
transcutaneous Auricular neurostimulation - Active, transcutaneous auricular neurostimulation - Sham
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Effect of the Enhanced Summer Food Service Program on Schoolchildren

NCT03118635
Conditions
Pediatric Obesity
Interventions
Intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
6 Years to 12 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Delayed Graft Function
Interventions
Furosemide, Placebo
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Parenting, Stress, Learning Disabilities, Child, Attention Difficulties
Interventions
SMART-3RP, Health Education Program
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

tAN to Mitigate Withdrawal Behaviors in Neonates

NCT04588519
Conditions
Neonatal Abstinence Syndrome
Interventions
Spark Biomedical Roo Transcutaneous Auricular Neurostimulation (tAN) System
Device
Lead sponsor
Spark Biomedical, Inc.
Industry
Eligibility
33 Weeks to 1 Year
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Depression
Interventions
Limbix Spark
Other
Lead sponsor
Limbix Health, Inc.
Industry
Eligibility
12 Years to 21 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pre-exposure Prophylaxis Implementation in Central-Eastern European Countries

NCT05323123
Conditions
Human Immunodeficiency Virus
Interventions
SPARK, HealthMpowerment, PrEP Education
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Male only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Hemophilia A
Interventions
SPK-8011, SPK-8016
Genetic
Lead sponsor
Spark Therapeutics, Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2032
U.S. locations
9
States / cities
Boston, Massachusetts • Madison, Mississippi • Kansas City, Missouri + 5 more
Completed Not applicable Interventional Results available

Symptom Screening Linked to Care Pathways

NCT04614662
Conditions
Pediatric Cancer, Quality of Life
Interventions
SPARK Symptom Screening Linked to Feedback to Providers
Behavioral
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
8 Years to 18 Years
Enrollment
445 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
20
States / cities
Phoenix, Arizona • Los Angeles, California • Redwood City, California + 17 more
Conditions
Obesity, Overweight, Weight Loss, Health Behavior
Interventions
Core behavioral weight loss intervention, Self-monitoring diet, Self-monitoring weight, Self-monitoring steps
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stanford, California
Conditions
Posttraumatic Stress Disorder, Opioid Use Disorder
Interventions
Sparrow Ascent tAN, Sparrow Ascent Active Sham
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cape Girardeau, Missouri
Conditions
Traumatic Brain Injury, Severe Traumatic Brain Injury, Disorders of Consciousness Due to Severe Brain Injury, Coma, Traumatic
Interventions
Dual-Site Transcutaneous Auricular Nerve Stimulation (taVNS + taTNS)
Device
Lead sponsor
Sima Mofakham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Stony Brook, New York
Completed Not applicable Interventional Accepts healthy volunteers

Fuel for Fun: Cooking With Kids Plus Parents and Play

NCT02491294
Conditions
Pediatric Obesity
Interventions
School, Family, About Eating
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
7 Years to 12 Years
Enrollment
2,640 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Fort Collins, Colorado
Conditions
Negative Symptoms in Schizophrenia, Schizophrenia, Schizoaffective Disorder
Interventions
SPARK
Device
Lead sponsor
North Shore Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Spinal Cord Injuries
Interventions
auricular nerve stimulation (aVNS), sham aVNS
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of Thiwáhe Gluwáš'Akapi Substance Use Prevention Program

NCT04222556
Conditions
Substance Use, Substance Abuse, Suicide
Interventions
Thiwáhe Gluwáš'akapi, Woyute Waśte
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 85 Years
Enrollment
552 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Pain, Depressive Symptoms, Aging
Interventions
SPARK
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Obesity & Overweight, Weight Management
Interventions
Culinary medicine classes, Medically Tailored Groceries, Shared Medical Appointments
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Childhood Cancer, Fertility Issues
Interventions
AYA SPARK
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Sexual Satisfaction, Sexual Function
Interventions
Spark Placebo Control 5.1, Spark Active Study Product 5.1 Usage
Dietary Supplement
Lead sponsor
Radicle Science
Industry
Eligibility
21 Years to 105 Years · Female only
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Del Mar, California