- Conditions
- Schizophrenia / Schizoaffective Disorder
- Interventions
- NST-SPARK
- Device
- Lead sponsor
- North Shore Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2028
- U.S. locations
- 2
- States / cities
- Glen Oaks, New York • Philadelphia, Pennsylvania
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Showing 25–48
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- Conditions
- Negative Symptoms in Schizophrenia, Schizophrenia, Schizoaffective Disorder
- Interventions
- SPARK
- Device
- Lead sponsor
- North Shore Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Cerebral Palsy
- Interventions
- Biomotum Spark: Robotic ankle resistance, Audiovisual Biofeedback, Multilevel Orthopedic Surgery
- Device · Procedure
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 7 Years to 18 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2029
- U.S. locations
- 1
- States / cities
- Saint Paul, Minnesota
- Conditions
- Hypertensive Disorders of Pregnancy, Preeclampsia, Gestational Hypertension
- Interventions
- Atorvastatin 10 mg, Placebo
- Drug
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 20 Years to 50 Years · Female only
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Posttraumatic Stress Disorder, Opioid Use Disorder
- Interventions
- Sparrow Ascent tAN, Sparrow Ascent Active Sham
- Device
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Cape Girardeau, Missouri
- Conditions
- Alzheimer Disease, Cognitive Impairment
- Interventions
- SPARK Test
- Device
- Lead sponsor
- Spark Neuro Inc.
- Industry
- Eligibility
- 55 Years to 85 Years
- Enrollment
- 185 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 7
- States / cities
- Loma Linda, California • Englewood, Colorado • Ocala, Florida + 4 more
- Conditions
- Prodromal Symptoms, Psychosis
- Interventions
- SPARK Coping
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Mother-child Relations, Parenting, Parent Child Abuse, Family Conflict, Parental Stress, Family Relations, Childhood Disorder of Social Functioning, Unspecified
- Interventions
- Therapeutic intervention
- Other
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 18 Years and older · Female only
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Overweight, Obesity, Hypertension, Prehypertension, Anxiety, Well-being, Depression, Low Physical Fitness, Psychological
- Interventions
- Fit2Play curriculum
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 6 Years to 14 Years
- Enrollment
- 5,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Cardiac Rehabilitation
- Interventions
- Fit Bit Blaze, Garmin Forerunner 235, Tom Tom Spark Cardio, Apple Watch
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Delayed Graft Function
- Interventions
- Furosemide, Placebo
- Drug
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- Obesity & Overweight, Weight Management
- Interventions
- Culinary medicine classes, Medically Tailored Groceries, Shared Medical Appointments
- Behavioral
- Lead sponsor
- Tufts University
- Other
- Eligibility
- 12 Years to 17 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- Hemophilia A
- Interventions
- SPK-8011, SPK-8016
- Genetic
- Lead sponsor
- Spark Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2032
- U.S. locations
- 9
- States / cities
- Boston, Massachusetts • Madison, Mississippi • Kansas City, Missouri + 5 more
- Conditions
- Spinal Cord Injuries
- Interventions
- auricular nerve stimulation (aVNS), sham aVNS
- Device
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Healthy Volunteers, Sympathetic Activity
- Interventions
- Lidocaine 2%
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia
- Interventions
- SPARK Cognitive Status Indicator (software support data collected via EEG)
- Diagnostic Test
- Lead sponsor
- Spark Neuro Inc.
- Industry
- Eligibility
- 65 Years to 90 Years
- Enrollment
- 600 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Depression
- Interventions
- Limbix Spark
- Other
- Lead sponsor
- Limbix Health, Inc.
- Industry
- Eligibility
- 12 Years to 21 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Substance Use, Substance Abuse, Suicide
- Interventions
- Thiwáhe Gluwáš'akapi, Woyute Waśte
- Behavioral
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 10 Years to 85 Years
- Enrollment
- 552 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Acute Lymphoblastic Leukemia
- Interventions
- Calaspargase pegol (S95015)
- Drug
- Lead sponsor
- Institut de Recherches Internationales Servier
- Other
- Eligibility
- 22 Years to 55 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 21
- States / cities
- Scottsdale, Arizona • Duarte, California • Los Angeles, California + 16 more
- Conditions
- Pediatric Obesity
- Interventions
- School, Family, About Eating
- Behavioral
- Lead sponsor
- Colorado State University
- Other
- Eligibility
- 7 Years to 12 Years
- Enrollment
- 2,640 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2018
- U.S. locations
- 1
- States / cities
- Fort Collins, Colorado
- Conditions
- Huntington Disease
- Interventions
- SPK-10001, Placebo Surgery Control
- Genetic · Other
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Eligibility
- 25 Years to 65 Years
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2035
- U.S. locations
- 5
- States / cities
- Boston, Massachusetts • Cincinnati, Ohio • Columbus, Ohio + 2 more
- Conditions
- Autism or Autistic Traits, Family Relations
- Interventions
- Transitioning Together (TT) / Juntos en la Transicion (JET), Usual autism transition care
- Behavioral
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 14 Years to 21 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Functional Endoscopic Sinus Surgery, Vagal Nerve Stimulation, Platelet Activation
- Interventions
- Spark Biomedical Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN) System
- Device
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Pediatric Cancer, Quality of Life
- Interventions
- SPARK Symptom Screening Linked to Feedback to Providers
- Behavioral
- Lead sponsor
- The Hospital for Sick Children
- Other
- Eligibility
- 8 Years to 18 Years
- Enrollment
- 445 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 20
- States / cities
- Phoenix, Arizona • Los Angeles, California • Redwood City, California + 17 more