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ClinicalTrials.gov public records Last synced Oct 19, 2026, 9:09 PM EDT

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Showing 433–456 of 729 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sedation Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Sedation on Eye Movements

NCT00646646
View directory record Official record
Conditions
Saccadic Eye Movements
Interventions
propofol, dexmedetomidine, Midazolam, saline placebo
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 19, 2017 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Phase 3 Interventional Results available

A Phase III Study of the Efficacy and Safety of Remimazolam Compared to Placebo and Midazolam in Colonoscopy Patients

NCT02290873
View directory record Official record
Conditions
Colonoscopy
Interventions
Remimazolam, Midazolam, Placebo
Drug
Lead sponsor
Paion UK Ltd.
Industry
Eligibility
18 Years and older
Enrollment
461 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
13
States / cities
Mobile, Alabama • Anaheim, California • Chula Vista, California + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 19, 2026, 9:09 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy

NCT02643979
View directory record Official record
Conditions
Obesity, Bariatrics, Sleep Apnea Syndromes, Gastric Bypass, Endoscopy
Interventions
Ketofol, Propofol, Saline
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy

NCT01895062
View directory record Official record
Conditions
Airway Obstruction, Apnea, Hypopnea
Interventions
Airway Management System (AMS)
Device
Lead sponsor
5i Sciences, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 19, 2026, 9:09 PM EDT
Withdrawn Phase 4 Interventional

Safety and Efficacy of Intravenous (IV) Dexmedetomidine During Flexible Bronchoscopy and Endobronchial Ultrasound

NCT00691886
View directory record Official record
Conditions
Pain
Interventions
dexmedetomidine hydrochloride
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2012 · Synced Oct 19, 2026, 9:09 PM EDT
Completed No phase listed Observational

Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation

NCT01430962
View directory record Official record
Conditions
Mediastinal Lymphadenopathies, Mediastinal Masses, Hilar Lymphadenopathies
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Oct 19, 2026, 9:09 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Implications of Anesthetics on Sleep Consolidation

NCT04329091
View directory record Official record
Conditions
Sleep
Interventions
Dexmedetomidine
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 35 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Injections of Autologous PRP in Women With Primary Ovarian Insufficiency

NCT03542708
View directory record Official record
Conditions
Primary Ovarian Insufficiency, Premature Menopause
Interventions
A-PRP
Procedure
Lead sponsor
Center for Human Reproduction
Other
Eligibility
21 Years to 40 Years · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study to Assess the Amnesic Properties of Propofol in Pediatric Patients

NCT02278003
View directory record Official record
Conditions
Pediatric Pateints, Amnesic Properties of Propofol
Interventions
memory test, Propofol
Other · Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
4 Years to 14 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2018 · Synced Oct 19, 2026, 9:09 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Enhanced Recovery Pathway for Endoscopy

NCT04983498
View directory record Official record
Conditions
Enhanced Recovery Pathway, Endoscopy
Interventions
Ondansetron 4 MG, Lactated Ringers, Intravenous, Early Mobilization, Early PO Intake
Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 19, 2026, 9:09 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy

NCT01782014
View directory record Official record
Conditions
Screening Colonoscopy
Interventions
colonoscopy
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Phase 3 Interventional

An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Flexible Bronchoscopy

NCT00306722
View directory record Official record
Conditions
Bronchoscopy, Anesthesia
Interventions
AQUAVAN® (fospropofol disodium) Injection
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
25
States / cities
Mobile, Alabama • Phoenix, Arizona • Laguna Hills, California + 20 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2008 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Not applicable Interventional

The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke

NCT03805308
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Intra-arterial Therapy
Procedure
Lead sponsor
Mercy Health Ohio
Other
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
43
States / cities
Little Rock, Arkansas • Los Angeles, California • Pomona, California + 39 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Oct 19, 2026, 9:09 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Dex as Analgesic Adjuvant in OSA Patients

NCT03613558
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Dexmedetomidine, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 19, 2026, 9:09 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia

NCT03781115
View directory record Official record
Conditions
Schizophrenia
Interventions
Ziprasidone, Olanzapine, Placebo Comparator
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Phase 3 Interventional Results available

Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are naïve to, Intolerant of, or Incomplete Responders to Omalizumab (LIBERTY-CSU CUPID)

NCT04180488
View directory record Official record
Conditions
Chronic Spontaneous Urticaria
Interventions
Dupilumab SAR231893, Placebo, non sedating H1-antihistamine
Drug
Lead sponsor
Sanofi
Industry
Eligibility
6 Years to 80 Years
Enrollment
397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
16
States / cities
Los Angeles, California • Sarasota, Florida • Sweetwater, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Oct 19, 2026, 9:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

CT Residual Gastric Fluid Volume

NCT02239068
View directory record Official record
Conditions
Clinical CT Abdomen/Pelvic With Oral Contrast and Sedation
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Month to 10 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2023
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Phase 4 Interventional

Impact of Topical Pharyngeal Anesthetics on Discharge of the Patients When Used in Conjunction With Propofol Sedation in Routine EGD's

NCT02507440
View directory record Official record
Conditions
Topical Anesthesia
Interventions
Lidocaine, Placebo, Propofol
Drug
Lead sponsor
Bassett Healthcare
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cooperstown, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of an Algorithm to Determine IV Sedation Dosing During First-trimester Surgical Abortion

NCT01994317
View directory record Official record
Conditions
Pregnancy, Unplanned
Interventions
Algorithm, Standard care
Other
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2015 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Not applicable Interventional Results available

Reduction of Claustrophobia and Patient Motion After Training of MRI Personnel in Comfort TalkTM

NCT01563198
View directory record Official record
Conditions
Claustrophobia, Complication of Diagnostic Procedure
Interventions
Comfort Talk®
Behavioral
Lead sponsor
Hypnalgesics, LLC
Industry
Eligibility
Not listed
Enrollment
97,712 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
4
States / cities
Boston, Massachusetts • Brookline, Massachusetts • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 14, 2017 · Synced Oct 19, 2026, 9:09 PM EDT
Withdrawn Phase 2Phase 3 Interventional Accepts healthy volunteers

Nitrous Oxide for Pain Management During IUD Insertion in Nulliparous Adolescent Women

NCT04089852
View directory record Official record
Conditions
Contraceptive Devices, Long-Acting Reversible Contraception, Analgesia, Adolescent Health, Gynecology
Interventions
Nitrous oxide gas for inhalation, Oxygen Gas for Inhalation
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 24 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2022 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Not applicable Interventional

Preventing Hypoxemia With Manual Ventilation During Endotracheal Intubation (PreVent) Trial

NCT03026322
View directory record Official record
Conditions
Respiratory Failure, Respiratory Failure With Hypoxia, Endotracheal Intubation
Interventions
Manual Ventilation, No Manual Ventilation
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
5
States / cities
Birmingham, Alabama • New Orleans, Louisiana • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2018 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Phase 4 Interventional

Comparison of Intravenous V/S Nasal Atomizer Delivery of Midazolam for Conscious Sedation for No-scalpel Vasectomy

NCT06449365
View directory record Official record
Conditions
Vasectomy, Sedation
Interventions
midazolam by nasal atomizer, intravenous midazolam
Device · Drug
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years to 85 Years · Male only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 19, 2026, 9:09 PM EDT
Completed Not applicable Interventional Results available

Post-Operative Delirium in Elderly Surgical Patients

NCT00590707
View directory record Official record
Conditions
Hip Fractures, Delirium
Interventions
Deeper sedation, Moderate sedation
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 11, 2018 · Synced Oct 19, 2026, 9:09 PM EDT