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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:50 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 77 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Self-Help Manual Clear all
Completed Not applicable Interventional

Behavioral Activation + Occupational Therapy

NCT05600465
View directory record Official record
Conditions
Multiple Chronic Conditions, Disability Physical
Interventions
Behavioral Activation + Occupational Therapy, Enhanced Usual Care
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
60 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Recruiting Not applicable Interventional

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

NCT06593652
View directory record Official record
Conditions
Alcohol Use, Adolescent, Mild Alcohol Use Disorder, Mild Substance Use Disorder
Interventions
Teen Intervene - Adolescent Only, Teen Intervene with Caregiver Session, Family Check Up
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 17 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Active, not recruiting Not applicable Interventional

Pain Self-Management and Treatment Engagement for Patients Taking Opioids

NCT06855732
View directory record Official record
Conditions
Chronic Pain, Opioid Use Disorder, Opioid Misuse and Addiction
Interventions
Usual Care, Pain Self-Management
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
17
States / cities
Baltimore, Maryland • Allison Park, Pennsylvania • Blawnox, Pennsylvania + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Not applicable Interventional

Counseling to Reduce Children's SHS Exposure: A Trial With Maternal Smokers

NCT02117947
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Behavioral Counseling, Self-help control
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Problem Solving Training for Care Partners of Adults With Traumatic Brain Injury

NCT03739450
View directory record Official record
Conditions
Care Partners of Patients With Traumatic Brain Injury (TBI)
Interventions
Problem Solving Training (PST), Education
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
4
States / cities
East Hanover, New Jersey • Edison, New Jersey • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing a Patient Navigation Intervention for PrEP Continuum of Care Among Young Latino MSM (PrEParate)

NCT04048382
View directory record Official record
Conditions
HIV/AIDS
Interventions
Patient Navigation, Usual Care
Behavioral · Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 29 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 20, 2026, 6:50 AM EDT
Active, not recruiting Not applicable Interventional

Smoking Cessation Intervention for Cancer Patients

NCT00575718
View directory record Official record
Conditions
Newly Diagnosed Cancer Patients
Interventions
Hospital Counseling + Nicotine Replacement Therapy. questionaires, Hospital Counseling + Nicotine Replacement + Presurgical Scheduled Reduced Smoking, questionaires
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Not applicable Interventional

Treatment for Persistently Fatigued Cancer Survivors: A Randomized Controlled Trial With Biomarker Response

NCT01919853
View directory record Official record
Conditions
Fatigue
Interventions
Mindfulness-Based Stress Reduction, Attention Control
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
4
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 20, 2026, 6:50 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Development of Psychotherapeutic Interventions for Parents Who Lost a Child

NCT02153619
View directory record Official record
Conditions
Parents Who Have Lost a Child
Interventions
Meaning-Centered Grief Therapy (MCGT), Supportive Psychotherapy (SP), questionnaires assessments
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Recruiting Not applicable Interventional

ACT With CF Self-Help Toolkit

NCT07436351
View directory record Official record
Conditions
Cystic Fibrosis (CF), Depressive and Anxiety Disorders, Psychological Flexibility
Interventions
ACT with CF Self-Help Toolkit, Waitlist
Behavioral · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Phase 2 Interventional

Low-intensity Stepped Care for Internalizing Distress

NCT05441111
View directory record Official record
Conditions
Depression, Anxiety, Emotion Regulation
Interventions
Common Elements Toolbox, Doing What Matters in Times of Stress: An Illustrated Guide, Guided self-help
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 20, 2026, 6:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Supporting Health in Veterans With Heart Failure

NCT05839067
View directory record Official record
Conditions
Heart Failure
Interventions
Care-HF
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
4
States / cities
Gainesville, Florida • Togus, Maine • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Three Different Dietary Messages on Dietary Intake and Health in Families

NCT01510678
View directory record Official record
Conditions
Obesity
Interventions
Increase Fruits and Vegetables, Decrease Snack Foods, Increase Fruits and Vegetables and Decrease Snack Foods
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
6 Years to 12 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
2
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Active, not recruiting Not applicable Interventional

Self-Help Group for the Treatment of Hoarding Disorder

NCT01585896
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Self-Help Group
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2027
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimal TTM Tailoring for Population Cessation

NCT01544010
View directory record Official record
Conditions
Smoking Cessation
Interventions
Stage-Tailored Manual, Stage Tailored Feedback Report, Moderate TTM-Tailored Feedback Report, Full TTM-Tailored Feedback Report, Enhanced TTM+Addiction Tailored Feedback Report
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
3,006 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Kingston, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Oct 20, 2026, 6:50 AM EDT
Not listed Phase 1Phase 2 Interventional

TRT in Combination With Electrical Stimulation and Standing: Effect on Muscle and Bone in Spinal Cord Injured Males

NCT02317640
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Testosterone Gel applied by a pump, Stand Training, Electrical Stimulation
Drug · Other · Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 58 Years · Male only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 20, 2026, 6:50 AM EDT
Not yet recruiting Not applicable Interventional

Virtual Group Therapy for IBD Patients With Anxiety and Depression

NCT07796568
View directory record Official record
Conditions
Crohn's Disease (CD), Ulcerative Colitis (UC), Inflammatory Bowel Diseases (IBD), Anxiety, Depression
Interventions
Group Psychotherapy Intervention
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Recruiting Phase 1 Interventional

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

NCT06513819
View directory record Official record
Conditions
Hiv, Alcohol Drinking, Fall, Cannabis Use
Interventions
Information Motivation Behavioral and Motivational Interviewing (IMB-MI) technique
Behavioral
Lead sponsor
Yale University
Other
Eligibility
50 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Not applicable Interventional

Use of Audio Recordings of Self-Hypnosis and Meditation for Fatigue Management in Multiple Sclerosis

NCT04688710
View directory record Official record
Conditions
Multiple Sclerosis, Fatigue
Interventions
Self-Hypnosis (HYP), Mindfulness Meditation (MM)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 17, 2024 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Being Responsible for Ourselves HIV Risk Reduction for Black MSM

NCT02561286
View directory record Official record
Conditions
Human Immunodeficiency Virus Infection (HIV), Sexually Transmitted Disease (STD)
Interventions
BRO HIV Risk Reduction Intervention, Health Promotion Intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Male only
Enrollment
595 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 29, 2015 · Synced Oct 20, 2026, 6:50 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Puerto Rican Obesity Intervention for Men

NCT06440551
View directory record Official record
Conditions
Obesity
Interventions
TeleSalud Healthy Eating- Physical Activity/Sedentary Behavior (HE-PA/SB), TeleSalud General Health Intervention
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
35 Years and older · Male only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 20, 2026, 6:50 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Treatment Study Comparing Two Non-Drug, Self-Help Treatment of Chronic Insomnia.

NCT00310284
View directory record Official record
Conditions
Insomnia
Interventions
Computerized delivery of cognitive-behavioral treatment of insomnia, Self-help manual to improve insomnia symptoms
Behavioral
Lead sponsor
PICS, Inc.
Other
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
1
States / cities
Reston, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2006 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Capitalizing on a Teachable Moment to Promote Smoking Cessation

NCT02276664
View directory record Official record
Conditions
Smoking Cessation
Interventions
Self-Help (SHI), Usual Care (UC)
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Oct 20, 2026, 6:50 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treatment of Binge Eating in Obese Patients in Primary Care

NCT00537810
View directory record Official record
Conditions
Obesity, Binge Eating
Interventions
Sibutramine, Placebo, Self-help CBT + Sibutramine, Self-help CBT + Placebo
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
3
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 18, 2021 · Synced Oct 20, 2026, 6:50 AM EDT