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ClinicalTrials.gov public records Last synced Nov 11, 2026, 1:20 PM EST

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Showing 1–24 of 517 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sepsis Clear all

Conditions: Infection, Bacterial Infection, Sepsis
Interventions: Procalcitonin assay - B.R.A.H.M.S PCT sensitive Kryptor; Device
Lead sponsor: Brahms AG; Industry
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 3
States / cities: St Louis, Missouri • Camden, New Jersey • Providence, Rhode Island

Conditions: Infection, Sepsis
Interventions: Not listed
Lead sponsor: BioMérieux; Industry
Eligibility: 18 Years and older
Enrollment: 815 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 4
States / cities: Aurora, Colorado • Boston, Massachusetts • Nashville, Tennessee + 1 more

Conditions: Dental Caries in Children
Interventions: Modified CariesCare International management; Procedure
Lead sponsor: Universidad El Bosque, Bogotá; Other
Eligibility: 3 Years to 8 Years
Enrollment: 409 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Indianapolis, Indiana • Boston, Massachusetts

Conditions: Sepsis
Interventions: Zinc; Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Nosocomial Bacteremia, Nosocomial Fungemia, MRSA Colonization, MRSA Infection, VRE Colonization, VRE Infection
Interventions: Daily bathing with Chlorhexidine based product; Behavioral
Lead sponsor: Hunter Holmes Mcguire Veteran Affairs Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 5,300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 4
States / cities: Baltimore, Maryland • St Louis, Missouri • New York, New York + 1 more

Conditions: Gram-Positive Bacterial Infections, Vancomycin, Pharmacokinetics, Pharmacodynamics
Interventions: Computer Decision Support Tool Intervention Group, Matched Historical Controls; Device · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: Up to 18 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sepsis
Interventions: personalized dosing adjustment of vancomycin; Other
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 1 Month to 17 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Delirium, Impaired Cognition, Long Term Psychologic Disorders
Interventions: Haloperidol, Ziprasidone, Placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 566 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2018
U.S. locations: 16
States / cities: Denver, Colorado • New Haven, Connecticut • Indianapolis, Indiana + 12 more

Conditions: Severe Sepsis
Interventions: S.A.F.E.BT; Device
Lead sponsor: B. Braun Medical Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 2
States / cities: Lexington, Kentucky • Baltimore, Maryland

Conditions: Early Onset Sepsis, Preterm Neonates, NICU, Ampicillin, Safety and Pharmacokinetics
Interventions: Ampicillin prescribed by provider per standard of care for evaluation of early onset sepsis; Drug
Lead sponsor: Duke University; Other
Eligibility: 0 Days to 7 Days
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Sepsis, Premature Birth
Interventions: Not listed
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 0 Days to 2 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Kidney Stone, Kidney Calculi, Urinary Tract Obstruction, Infection, Sepsis
Interventions: Initial clinical and laboratory evaluation; Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 477 participants
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Dallas, Texas

Conditions: Sepsis, Septic Shock, Metabolic Disturbance
Interventions: vitamin C, vitamin B1, hydrocortisone, Normal saline; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 13
States / cities: Phoenix, Arizona • Boston, Massachusetts • Cambridge, Massachusetts + 6 more

Conditions: Candidemia, Mycoses, Fungal Infection, Invasive Candidiases
Interventions: Rezafungin for Injection, Caspofungin, Fluconazole, intravenous placebo, oral placebo; Drug
Lead sponsor: Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA); Industry
Eligibility: 18 Years and older
Enrollment: 199 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 19
States / cities: Birmingham, Alabama • Sacramento, California • Atlanta, Georgia + 16 more

Conditions: Sterile Catheter, Catheter-related Bloodstream Infections, Dialysis Catheter, Dialysis
Interventions: Catheter Caps Case (C3); Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Acute Kidney Injury, Chronic Kidney Disease, Hypertension
Interventions: Iodohippurate, 24 hour ambulatory Blood Pressure, Peripheral Arterial Tonometry, Pulse Wave Velocity, Gadolinium; Drug · Procedure
Lead sponsor: University of Florida; Other
Eligibility: 7 Years to 17 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Puerperal: [Major Infection] or [Sepsis]
Interventions: Diagnostic Breath Analysis; Device
Lead sponsor: Landon Pediatric Foundation; Other
Eligibility: 18 Years to 80 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Ventura, California

Conditions: Sepsis
Interventions: Capillary Refill Assessment; Device
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Healthcare-Associated Pneumonia, Sepsis
Interventions: antimicrobial initiation; Other
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years to 99 Years
Enrollment: 186 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Severe Sepsis, Septic Shock, Microcirculation
Interventions: Sidestream Dark Field (SDF), Near Infrared Spectroscopy (NIRS); Device
Lead sponsor: Mercy Research; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Adrenal Insufficiency
Interventions: Not listed
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 15 Years to 65 Years
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Sepsis, Congenital Diaphragmatic Hernia, Neonatal Cardiopulmonary Failure
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: Up to 2 Months
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 2
States / cities: Salt Lake City, Utah

Conditions: Sepsis, Infection, Septic Shock
Interventions: HBP lab test; Other
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years and older
Enrollment: 1,055 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Sepsis
Interventions: Resatorvid, Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years and older
Enrollment: 277 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 49
States / cities: Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 46 more

Search by objective public record fields.

Procalcitonin Level to Discontinue Antibiotics on ICU Patients With no Obvious Site of Infection

Early Identification of SEPsis SIGNs in Emergency Department

Pandemic-adapted Caries Care Multicentre Single-group Interventional Study

The Impact of Zinc Supplementation on Innate Immunity and Patient Safety in Sepsis

The Impact of Chlorhexidine-Based Bathing on Nosocomial Infections

Clinical Decision Support Tool for Vancomycin Dosing in Children

Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention

The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study

S.A.F.E.BT System Extracorporeal Treatment With DIAPACT CRRT

Optimizing PreTerm Infant Ampicillin Dosing

Predictors of Sepsis in Ex-Preterm Infants

Evaluation of Infection in Obstructing Urolithiasis

Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis

Dialysis Catheter Caps Case Feasibility Study

Severe Sepsis in Children - IMPRESS-C

Diagnostic Breath Analysis Study to Detect Sepsis

Digital Capillary Refill for Monitoring of Sepsis

Trial of Antimicrobial Restraint in Presumed Pneumonia

The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients

Adrenal Function in Critical Illness

Inflammatory Cytokine Quantification in Infants

Evaluation of the Heparin Binding Protein Levels in Sepsis

Efficacy & Safety of Resatorvid in Adults With Severe Sepsis