Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 5:37 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 517 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sepsis Clear all

Conditions: Severe Sepsis
Interventions: Talactoferrin alfa, Placebo; Drug
Lead sponsor: Agennix; Industry
Eligibility: 18 Years and older
Enrollment: 190 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 27
States / cities: Loma Linda, California • Sacramento, California • Sylmar, California + 20 more

Conditions: Sepsis
Interventions: Not listed
Lead sponsor: Matthew Exline; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Sepsis
Interventions: Implementation and evaluation of a sepsis sub-phenotyping algorithm; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 1,916 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 4
States / cities: Atlanta, Georgia • Johns Creek, Georgia

Conditions: Cancer, Leukemia, Stem Cell Transplantation
Interventions: C-Reactive Protein levels; Behavioral
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 6 Months to 20 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Sepsis, Critical Illness, ICU-acquired Muscle Weakness, ICU-acquired Weakness, ICUAW, Sarcopenia, Secondary Sarcopenia
Interventions: Electrical Muscle Stimulation System; Device
Lead sponsor: Health Discovery Labs; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 3
States / cities: Rochester, Minnesota • Austin, Texas

Conditions: Sepsis, Necrotising Enterocolitis Neonatal
Interventions: No Intervention: Observational Cohort; Other
Lead sponsor: University of Virginia; Other
Eligibility: Not listed
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Severe Sepsis, Septic Shock
Interventions: NICOM/FloTrac, Crystalloid Fluid Challenge; Device · Other
Lead sponsor: Santa Barbara Cottage Hospital; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Severe Sepsis
Interventions: Acetaminophen, placebo; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Sepsis, Deterioration, Clinical, Critical Illness, Early Warning Score
Interventions: Algorithm-triggered sepsis alert with structured critical care team activation; Other
Lead sponsor: Patricks Lyons; Other
Eligibility: 18 Years and older
Enrollment: 3,700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Congenital Heart Disease, Sepsis, Infection
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: Up to 5 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Sepsis, Community Acquired Pneumonia (CAP)
Interventions: OPT101, Placebo; Drug · Other
Lead sponsor: Op-T LLC; Industry
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Septicemia
Interventions: Initial Specimen Diversion Device (ISDD), Lab standard practice (LSP), Peripheral Intravenous Catheters (PIVC); Device · Procedure
Lead sponsor: Magnolia Medical Technologies, Inc.; Industry
Eligibility: 19 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cardiovascular Disease, Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection, Deep Sternal Infection, Mediastinitis, Thoracotomy, Conduit Harvest or Cannulation Site, Sepsis, Pneumonia
Interventions: There is no intervention. The investigators are interviewing cardiac surgery staff with knowledge of infection prevention.; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Glucose, Metabolism, Isotope Labeling, Immune System and Related Disorders, Critical Illness, Intensive Care Unit (ICU), Sepsis
Interventions: 13C6-Glucose; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Acute Respiratory Distress Syndrome (ARDS)
Interventions: Inhaled Carbon Monoxide at 100ppm (4 participants), Placebo for Inhaled Carbon Monoxide at 100ppm (2 participants), Inhaled Carbon Monoxide at 200ppm (4 participants), Placebo for Inhaled Carbon Monoxide at 200ppm (2 participants); Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 4
States / cities: Boston, Massachusetts • New York, New York • Durham, North Carolina

Conditions: Inpatient Hospitalization, Intensive Care Unit Admission, Inpatient Mortality, Sepsis and Septic Shock
Interventions: TriageGO-MDW Clinical Decision Support, Usual Care; Other
Lead sponsor: Stocastic, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 300,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Kansas City, Kansas • Kansas City, Missouri

Conditions: Bacterial Sepsis
Interventions: CPG 7909, J5-OMP Vaccine, Placebo; Biological · Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sepsis, Acute Kidney Injury Due to Sepsis, Acute Kidney Injury (Nontraumatic)
Interventions: Not listed
Lead sponsor: Northwell Health; Other
Eligibility: 1 Day to 18 Years
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Staphylococcus Aureus Bacteremia
Interventions: Ceftobiprole medocaril, Daptomycin; Drug
Lead sponsor: Basilea Pharmaceutica; Industry
Eligibility: 18 Years and older
Enrollment: 390 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 5
States / cities: Chula Vista, California • West Palm Beach, Florida • Butte, Montana + 2 more

Conditions: Sepsis
Interventions: Ascorbic Acid, Normal Saline; Drug · Other
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Second Degree Burn
Interventions: Mepilex, Silvadene; Device
Lead sponsor: Molnlycke Health Care AB; Industry
Eligibility: 5 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 10
States / cities: Los Angeles, California • Washington D.C., District of Columbia • Gainesville, Florida + 7 more

Conditions: Sepsis, Septic Shock, Sepsis-Associated Immune Dysregulation
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 100 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2037
U.S. locations: 1
States / cities: Falls Church, Virginia

Conditions: COPD, Congestive Heart Failure, Trauma, Sepsis, Stroke
Interventions: NexfinHD Monitor; Device
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Blood Stream Infections, MRSA Infections
Interventions: healthcare staff processes for infection prevention; Behavioral
Lead sponsor: MaineHealth; Other
Eligibility: Not listed
Enrollment: 175 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Portland, Maine

Search by objective public record fields.

Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis

Immune Suppression and Ventilator Associated Pneumonias

Novel Sepsis Sub-phenotypes Based on Trajectories of Vital Signs

C-Reactive Protein as a Predictor of Stem Cell Transplant Complications

MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients

Integrated Predictive Monitoring for Sepsis and Necrotizing Enterocolitis

Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock

Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis

Hospital-Onset Sepsis Systematic Detection and Structured Interventions

Pro-Calcitonin Levels Following Pediatric Cardiac Surgery

OPT101 in Patients With Community Acquired Pneumonia (CAP) With Sepsis

Study to Evaluate the Effectiveness of the Initial Specimen Diversion Device When Collected Through Peripheral Intravenous Catheters

Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (HAI)_2

Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells - Intensive Care Unit

Safety Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)

Linking Novel Diagnostics With Data-Driven Clinical Decision Support in the Emergency Department

Detoxified J5 Core Glycolipid/ Group B Meningococcal Outer Membrane Protein Vaccine for Gram-negative Bacterial Sepsis Administered With and Without Synthetic CPG Oligodeoxynucleotide 7909 Adjuvant

Renin Angiotensin Aldosterone System In Septic Kids

Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia

High Dose Intravenous Ascorbic Acid in Severe Sepsis

Evaluating the Cost-effectiveness, Efficacy, Safety and Tolerance of Mepilex® Ag Versus Silvadene®

Immune Dysregulation During Sepsis: A Natural History Cohort

Use of Non Invasive Hemodynamic Cardiovascular Monitoring to Evaluate Emergency Department Patients

Testing Spread and Implementation of Novel Methicillin Resistant Staphylococcal Aureus (MRSA)-Reducing Practices