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ClinicalTrials.gov public records Last synced Nov 12, 2026, 10:04 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 517 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sepsis Clear all

Conditions: Sepsis
Interventions: Pediatric sepsis screening tool (either algorithmic or manual); Diagnostic Test
Lead sponsor: Computer Technology Associates, Inc.; Industry
Eligibility: 3 Months to 45 Years
Enrollment: 12,961 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2029
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Sepsis, Severe Sepsis
Interventions: Intravenous fluid; Drug
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years and older
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 5
States / cities: Newark, Delaware • Boston, Massachusetts • Detroit, Michigan + 2 more

Conditions: Sepsis, Acute Kidney Injury, Septic Shock
Interventions: Subject management guided by NephroCheck® test, Standard of Care; Device · Other
Lead sponsor: BioMérieux; Industry
Eligibility: 21 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Shreveport, Louisiana • Boston, Massachusetts • New York, New York

Conditions: Systemic Inflammatory Response Syndrome (SIRS), Sepsis, Severe Sepsis, Septic Shock
Interventions: Severe Sepsis Management Bundle; Other
Lead sponsor: University of Tennessee; Other
Eligibility: 1 Month to 18 Years
Enrollment: 30,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Sepsis
Interventions: Continuous Renal Replacement Therapy; Procedure
Lead sponsor: Sunnybrook Health Sciences Centre; Other
Eligibility: 1 Year to 21 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 5
States / cities: Washington D.C., District of Columbia • St. Petersburg, Florida • Atlanta, Georgia + 2 more

Conditions: Severe Sepsis
Interventions: eritoran tetrasodium, Placebo; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2006
U.S. locations: 69
States / cities: Birmingham, Alabama • Mobile, Alabama • Mesa, Arizona + 66 more

Conditions: Sepsis, Thrombocytopenia
Interventions: Platelet transfusion, Saline; Biological · Other
Lead sponsor: Susan Smyth; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Antibiotic Resistant Infection, Nosocomial Infection, Pathogen Transmission, Nutrition Disorders, Critical Illness, Sepsis
Interventions: Inulin Oral Suspension, Placebo Oral Suspension, Broad-spectrum antibiotics; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: C.Surgical Procedure; Cardiac
Interventions: Acute normovolemic hemodilution, Standard care; Procedure
Lead sponsor: Università Vita-Salute San Raffaele; Other
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 2
States / cities: Oklahoma City, Oklahoma • Charlottesville, Virginia

Conditions: Sepsis, Acute Lung Injury(ALI)
Interventions: Not listed
Lead sponsor: University of Kentucky; Other
Eligibility: 18 Years to 99 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Sepsis-Induced Hypotension
Interventions: REGN7544, PB; Drug
Lead sponsor: Regeneron Pharmaceuticals; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 16
States / cities: Tucson, Arizona • New Haven, Connecticut • Atlanta, Georgia + 10 more

Conditions: Severe Sepsis
Interventions: Talactoferrin alfa, Placebo; Drug
Lead sponsor: Agennix; Industry
Eligibility: 18 Years and older
Enrollment: 1,280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 34
States / cities: Birmingham, Alabama • Mobile, Alabama • Maricopa, Arizona + 31 more

Conditions: Immune Response To Sepsis, Staphylococcus Aureus Infection
Interventions: Not listed
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Infection
Interventions: Not listed
Lead sponsor: Abbott Diagnostics Division; Industry
Eligibility: 18 Years and older
Enrollment: 872 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Severe Sepsis, Septic Shock, Microcirculation
Interventions: Sidestream Dark Field (SDF), Near Infrared Spectroscopy (NIRS); Device
Lead sponsor: Mercy Research; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome
Interventions: GM-CSF, Placebo; Drug · Other
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 1 Day to 17 Years
Enrollment: 141 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 25
States / cities: Little Rock, Arkansas • Los Angeles, California • Oakland, California + 21 more

Conditions: Systemic Inflammatory Response Syndrome
Interventions: Goal-directed Therapeutic Protocol; Procedure
Lead sponsor: Arkansas Children's Hospital Research Institute; Other
Eligibility: 1 Month to 17 Years
Enrollment: 230 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Catheter-related Bloodstream Infection
Interventions: Chlorhexidine-impregnated foam dressing; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 1,088 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Septic Shock
Interventions: hydrocortisone, Normal Saline; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 99 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Blood Stream Infection, Blood Stream Infections, Sepsis, Fungemia, Bacteremia
Interventions: UllCORE BSI Test; Diagnostic Test
Lead sponsor: Deepull Diagnostics S.L.; Industry
Eligibility: Not listed
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 10
States / cities: Orange, California • Tampa, Florida • Baltimore, Maryland + 7 more

Conditions: Sepsis, Septic Shock, Emergencies
Interventions: Septic Shock Clinical Decision Support, Clinical Diagnosis Only; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 1,345 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Laboratory-confirmed Bloodstream Infection, Central Line-associated Bloodstream Infections, Mucosal Barrier Injury
Interventions: Not listed
Lead sponsor: Boston Children's Hospital; Other
Eligibility: Not listed
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sepsis, Burn Injury, Wound Healing, Critical Illness, Multiple Organ Dysfunction Syndrome
Interventions: Observational Cohort (No Intervention); Other
Lead sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine; Other
Eligibility: 18 Years to 80 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 3
States / cities: Tampa, Florida • Atlanta, Georgia • Houston, Texas

Conditions: Infection, Hospital
Interventions: Passive disinfection device; Device
Lead sponsor: Solventum US LLC; Industry
Eligibility: 18 Years and older
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Maplewood, Minnesota

Search by objective public record fields.

Biomarker-enhanced Artificial Intelligence Based Pediatric Sepsis Screening Tool

Preemptive Resuscitation for Eradication of Septic Shock

A Study Looking at the Use of Biomarkers to Provide Early Indication of Acute Kidney Injury in Patients With Sepsis (Limiting AKI Progression In Sepsis)

Electronic Application of a Severe Sepsis Screening Tool and Management Bundle

Cytokine Removal by CRRT in Pediatric Sepsis

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis

The INFUSE Trial - Intervening With Platelet Transfusions in Sepsis

Inulin for Infections in the Intensive Care Unit

Acute Normovolemic Hemodilution in High Risk Cardiac Surgery Patients.

Recovery of Physical Function After Critical Illness In Older Adults

A Study of REGN7544 for the Treatment in Adult Patients With Sepsis-Induced Hypotension

Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis

Immune Resolution After Staphylococcus Aureus Bacteremia

Procurement of Human Specimens for the Evaluation of Early Markers of Sepsis

The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients

GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS

Goal-directed Resuscitative Interventions During Pediatric Inter-facility Transport (The GRIPIT Trial)

Reducing Catheter-Related Bloodstream Infections in the ICU With a Chlorhexidine-Impregnated Sponge (BIOPATCH)

Hemodynamic and Inflammatory Effects of Abrupt Versus Tapered Corticosteroid Discontinuation in Septic Shock

Evaluation of Diagnostic Accuracy and Clinical Performance of the UllCORE Bloodstream Infection (BSI) Test

Implementation Trial of Predictive Modeling to Enhance Diagnosis and Improve Treatment in Pediatric Septic Shock

Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections

TDAP in Burn Patients (Group 2)

Passive Disinfection Cap Compliance Study