- Conditions
- Obesity, Bariatric Surgery, Roux-en Y Gastric Bypass
- Interventions
- Digestive biopsy, Carvedilol 25mg, Serial blood sampling for PK analysis, Metoprolol 100 mg for CYP2D6 phenotyping, Simvastatin 40mg, Midazolam 2 mg for CYP3A4 phenotyping, Genotyping
- Procedure · Drug · Other
- Lead sponsor
- Natalia Valadares de Moraes
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Orlando, Florida
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- Conditions
- PPAP, Spine Fusion
- Interventions
- Preoperative Genotyping
- Diagnostic Test
- Lead sponsor
- Senthil Sadhasivam
- Other
- Eligibility
- 10 Years to 21 Years
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 5
- States / cities
- San Francisco, California • St. Petersburg, Florida • Indianapolis, Indiana + 1 more