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ClinicalTrials.gov public records Last synced Oct 28, 2026, 1:15 AM EDT

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Showing 361–384 of 1,658 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham (Control) Clear all
Not listed Not applicable Interventional

RejuvenAir® System Trial for COPD With Chronic Bronchitis

NCT03893370
View directory record Official record
Conditions
Chronic Bronchitis
Interventions
RejuvenAir System, Sham Control Procedure
Device
Lead sponsor
CSA Medical, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
26
States / cities
Scottsdale, Arizona • Mountain View, California • Sacramento, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Not applicable Interventional

Solace Stress Urinary inContinence Control Efficacy and Safety Study

NCT02210273
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
Solace Bladder Control (Vesair) Balloon, Solace Sham Treatment
Device
Lead sponsor
Solace Therapeutics, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
20
States / cities
Phoenix, Arizona • Tucson, Arizona • Denver, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stress, Sex, and the Generalization of Fear

NCT03786952
View directory record Official record
Conditions
Psychological Stress
Interventions
Stress immediately before learning in males, Sham control immediately before learning in males, Stress 30 minutes before learning in males, Sham control 30 minutes before learning in males, Stress immediately before learning in females, Sham control immediately before learning in females, Stress 30 minutes before learning in females, Sham control 30 minutes before learning in females
Behavioral
Lead sponsor
Ohio Northern University
Other
Eligibility
18 Years and older
Enrollment
606 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Ada, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 28, 2026, 1:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Focused Ultrasound for the Complex Patient

NCT06453109
View directory record Official record
Conditions
Opioid Use Disorder, Chronic Back Pain, Anxiety
Interventions
low intensity focused ultrasound (LIFU)
Device
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Oct 28, 2026, 1:15 AM EDT
Not listed Phase 2 Interventional

Autologous Stem Cell Study for Adult TBI (Phase 2b)

NCT02525432
View directory record Official record
Conditions
Brain Injuries, Traumatic, Brain Injuries, Acute, TBI (Traumatic Brain Injury)
Interventions
Placebo Infusion, Autologous BMMNC Infusion
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 55 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Phase 2Phase 3 Interventional

Corneal Collagen Cross-Linking for the Treatment of Progressive Keratoconus and Corneal Ectasia

NCT00567671
View directory record Official record
Conditions
Progressive Keratoconus, Corneal Ectasia
Interventions
Corneal collagen, Sham comparator
Procedure
Lead sponsor
Emory University
Other
Eligibility
14 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 2, 2010 · Synced Oct 28, 2026, 1:15 AM EDT
Terminated Phase 2 Interventional

The Application of Extremely Low Level Magnetic Fields as Adjunctive Treatment for Type II Diabetes

NCT00982293
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Resonator device, Resonator device - sham
Device
Lead sponsor
pico-tesla Magnetic Therapies, LLC
Industry
Eligibility
21 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Littleton, Colorado
Source: ClinicalTrials.gov public record
Updated May 5, 2011 · Synced Oct 28, 2026, 1:15 AM EDT
Active, not recruiting Not applicable Interventional

CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial

NCT03455725
View directory record Official record
Conditions
Refractory Angina, Chronic Myocardial Ischemia
Interventions
CardiAMP Cell Therapy System, Sham Treatment
Device · Other
Lead sponsor
BioCardia, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Gainesville, Florida • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 28, 2026, 1:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA

NCT03887481
View directory record Official record
Conditions
Logopenic Progressive Aphasia, Primary Progressive Aphasia
Interventions
High-definition active tDCS (HD-tDCS) + "Repeat After Me" (RAM) Treatment, Sham + "Repeat After Me" (RAM) Treatment
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Not applicable Interventional

Auricular Point Acupressure to Self-Manage Chronic Pain or Aromatase Inhibitor Musculoskeletal Symptoms in Breast Cancer Survivors: Effectiveness and Scientific Underpinnings

NCT03697200
View directory record Official record
Conditions
Aromatase Inhibitor, Musculoskeletal Symptoms, Postmenopausal Breast Cancer Survivors
Interventions
APA, Sham APA control, Education control
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Not applicable Interventional

The Effects of Journaling on Health-Related Mood and Clinical Outcomes in Post-MI Patients

NCT02481544
View directory record Official record
Conditions
Myocardial Infarction, Psychosocial Factors
Interventions
Gratitude Journaling Plus SOC, Memorable Events Journaling Plus SOC
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
35 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate PEMF Therapy on Experimentally Inducted Pain in Subjects With Painful Peripheral Diabetic Neuropathy

NCT02809911
View directory record Official record
Conditions
Painful Peripheral Diabetic Neuropathy
Interventions
Provant
Device
Lead sponsor
Regenesis Biomedical, Inc.
Industry
Eligibility
22 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2017 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Not applicable Interventional Results available

Inspiratory Muscle Rehabilitation in Children With Obesity

NCT05412134
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Pro2 - 75% of participant's MIP, Pro2 - 15% of participant's MIP
Device
Lead sponsor
Duke University
Other
Eligibility
8 Years to 17 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 28, 2026, 1:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Brain Criticality, Oculomotor Control, and Cognitive Effort

NCT06344559
View directory record Official record
Conditions
Healthy
Interventions
transcranial magnetic stimulation
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Not applicable Interventional

Safety and Efficacy Study of the Neurent Medical NEUROMARK™ System in Subjects With Chronic Rhinitis

NCT04769596
View directory record Official record
Conditions
Chronic Rhinitis
Interventions
NEUROMARK™ System, Sham Device
Device
Lead sponsor
Neurent Medical
Industry
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
8
States / cities
Birmingham, Alabama • Roseville, California • Colorado Springs, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Repetitive Transcranial Magnetic Stimulation on Resting State Brain Activity in Schizophrenia

NCT01620086
View directory record Official record
Conditions
Schizophrenia
Interventions
Active Repetitive Transcranial Magnetic Stimulation 1 Hz, Active Repetitive Transcranial Magnetic Stimulation 10 Hz, Active control site Repetitive Transcranial Magnetic Stimulation at 1Hz, Sham control site Repetitive Transcranial Magnetic Stimulation, Active control site Repetitive Transcranial Magnetic Stimulation at 10 Hz
Device
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Oct 28, 2026, 1:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural Control of Gait & Navigation in ADRD

NCT06501820
View directory record Official record
Conditions
Aging
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 28, 2026, 1:15 AM EDT
Suspended Not applicable Interventional

Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes

NCT04419779
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham)
Device
Lead sponsor
Fractyl Health Inc.
Industry
Eligibility
21 Years to 70 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
51
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Los Angeles, California + 39 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Not applicable Interventional

Implant for Augmentation of Cerebral Blood Flow Trial, Effectiveness and Safety in a 24 Hour Window

NCT00826059
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Active Sphenopalatine Ganglion (SPG) Stimulation, Sham Sphenopalatine Ganglion (SPG) Stimulation
Device
Lead sponsor
BrainsGate
Industry
Eligibility
40 Years to 85 Years
Enrollment
1,078 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
7
States / cities
Sarasota, Florida • Winfield, Illinois • Greensboro, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Phase 1Phase 2 Interventional

Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder

NCT03382379
View directory record Official record
Conditions
Amphetamine Use Disorders
Interventions
Active transcranial Direct Current Stimulation (tDCS), Sham transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 7, 2019 · Synced Oct 28, 2026, 1:15 AM EDT
Active, not recruiting Not applicable Interventional

Flow Regulation by Opening the SepTum in Patients With Heart Failure; a Prospective, Randomized, Sham-controlled, Double-blind, Global Multicenter Study

NCT05136820
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions
Atrial Flow Regulator, Sham Comparator
Device
Lead sponsor
Occlutech International AB
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
2
States / cities
Phoenix, Arizona • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 8, 2025 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Phase 3 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (YOSEMITE)

NCT03622580
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
Aflibercept, Faricimab, Sham Procedure
Drug · Procedure
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
940 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
85
States / cities
Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 78 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 28, 2026, 1:15 AM EDT
Completed Phase 2 Interventional

Attention Bias Modification for Anxiety: A Randomized Control Trial With Biomarkers

NCT02200003
View directory record Official record
Conditions
Anxiety
Interventions
attention bias modification for anxiety
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 40 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 28, 2026, 1:15 AM EDT
Withdrawn Phase 1 Interventional

Efficacy of TDCS for Treating Working Memory Dysfunction and Depression in Temporal Lobe Epilepsy

NCT02268578
View directory record Official record
Conditions
Epilepsy
Interventions
Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
Device · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2016 · Synced Oct 28, 2026, 1:15 AM EDT