Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 4, 2026, 1:57 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1297–1320 of 1,663 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham (Control) Clear all

Conditions: Fibromyalgia
Interventions: Lymphatic Enhancement Technology (LET), Sham Lymphatic Enhancement Technology (LET); Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Optic, Atrophy, Hereditary, Leber
Interventions: GS010, Sham Intravitreal Injection; Biological · Device
Lead sponsor: GenSight Biologics; Industry
Eligibility: 15 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 3
States / cities: Los Angeles, California • Atlanta, Georgia • Philadelphia, Pennsylvania

Conditions: Aphasia, Cerebrovascular Stroke
Interventions: Transcranial Magnetic Stimulation, Repetitive; Device
Lead sponsor: Boston University; Other
Eligibility: 45 Years to 80 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2013
U.S. locations: 3
States / cities: Boston, Massachusetts • Philadelphia, Pennsylvania

Conditions: Female Sexual Dysfunction
Interventions: percutaneous tibial nerve stimulation (PTNS), Sham procedure; Device
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Vitreomacular Adhesion Including Macular Hole
Interventions: Ocriplasmin, Sham injection; Drug · Other
Lead sponsor: ThromboGenics; Industry
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 25
States / cities: Phoenix, Arizona • Beverly Hills, California • Sacramento, California + 22 more

Conditions: Anesthesia
Interventions: Continuous Adductor Canal Catheter (ACC), Adductor Canal block with sham catheter; Device
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 65 Years
Enrollment: 94 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Acupuncture, Pain, Range of Motion
Interventions: One Needle Hand Acupuncture with Movement, One Needle Hand Acupuncture without Movement, Control Acupuncture with Movement; Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 99 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Chesterfield, Missouri

Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Interventions: RelieVRx, Sham-VR, No-VR (natural history control); Device · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 88 Years
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Non-Infectious Uveitis
Interventions: FAI insert, Sham injection; Drug
Lead sponsor: EyePoint Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 16
States / cities: Beverly Hills, California • Sacramento, California • Torrance, California + 13 more

Conditions: Fibromyalgia, Healthy Volunteers
Interventions: EEG, Neuroimaging EEG/fMRI (Aim 1), HD-tDCS treatments, Sham HD-tDCS treatments, Neuroimaging EEG/fMRI (Aim 3); Diagnostic Test · Device
Lead sponsor: University of Michigan; Other
Eligibility: 19 Years to 74 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Breast Carcinoma, Recurrent Breast Carcinoma, Stage IV Breast Cancer
Interventions: Bevacizumab, Carboplatin, Paclitaxel, Placebo, Trastuzumab; Biological · Drug · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2015
U.S. locations: 373
States / cities: Jonesboro, Arkansas • Castro Valley, California • Emeryville, California + 236 more

Conditions: COPD, COPD - Chronic Obstructive Pulmonary Disease
Interventions: Activated ROAM System with User Feedback, Sham Comparator; Device
Lead sponsor: Barron Associates, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Stress Disorders, Post-Traumatic
Interventions: taVNS; Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Manhasset, New York

Conditions: Ankyloglossia, Breast Feeding, Enlarged Labial Frenum
Interventions: Lingual Frenotomy, Labial Frenotomy, Sham Procedure; Procedure
Lead sponsor: University of South Florida; Other
Eligibility: Up to 2 Weeks
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Migraine
Interventions: Precision; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 179 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2018
U.S. locations: 15
States / cities: Denver, Colorado • Stamford, Connecticut • Augusta, Georgia + 11 more

Conditions: Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions: Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage; Device · Dietary Supplement
Lead sponsor: Embry-Riddle Aeronautical University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Daytona Beach, Florida

Conditions: Bipolar Depression
Interventions: Deep TMS Treatment, Sham Treatment; Device
Lead sponsor: Brainsway; Industry
Eligibility: 22 Years to 68 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2021
U.S. locations: 9
States / cities: Juno Beach, Florida • Palm Beach, Florida • Royal Palm Beach, Florida + 6 more

Conditions: Major Depressive Disorder
Interventions: NEST-1 (NeoSync EEG Synchronized TMS), SHAM; Device
Lead sponsor: Wave Neuroscience; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 18
States / cities: Los Angeles, California • San Diego, California • Torrance, California + 15 more

Conditions: Constipation, Diabetes Mellitus, Colonic Transit, Gastric Emptying
Interventions: Pyridostigmine, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Septic Shock
Interventions: Low Level Transcutaneous Vagus Nerve Stimulation; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Post Operative Delirium, Cognitive Impairment, Vagus Nerve Stimulation, Depression
Interventions: Transcutaneous vagal nerve stimulation, Sham (No Treatment); Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: Transcranial Direct Current Stimulation (tDCS), Sham tDCS + anodal tDCS; Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years to 80 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Myocardial Infarction, Psychosocial Factors
Interventions: Gratitude Journaling Plus SOC, Memorable Events Journaling Plus SOC; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 35 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Aphasia
Interventions: Repetitive Transcranial Magnetic Stimulation, Sham TMS; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 75 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Search by objective public record fields.

LET for Fibromyalgia

Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE)

Transcranial Magnetic Stimulation to Improve Speech in Aphasia

Trial of Tibial Nerve Stimulation for Treating Sexual Dysfunction

Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole

Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service

One Needle Hand Acupuncture for MSK Disorders

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)

Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert

Explosive Synchronization of Brain Network Activity in Chronic Pain

Bevacizumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER-2/NEU

Respiratory Oxygen Adherence Monitor for Chronic Obstructive Pulmonary Disease Patients

taVNS to Reduce PTSD Symptoms in WTC Responders

Prospective Evaluation of Lingual Frenotomy in Newborns With Simultaneous Lip Tie for the Relief of Breastfeeding Pain.

Treatment for Migraines With an Implantable Device

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

Safety and Efficacy Study of Deep Transcranial Magnetic Stimulation in Bipolar Depression

Synchronized Transcranial Magnetic Stimulation (sTMS) in Major Depressive Disorder

Use of Pyridostigmine for Constipation in Diabetics

Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis

Effects of Transcutaneous Vagal Nerve Stimulation on Post-Surgical Return to Consciousness, Delirium, and Depression

Remotely Supervised tDCS for Slowing ALS Disease Progression

The Effects of Journaling on Health-Related Mood and Clinical Outcomes in Post-MI Patients

TMS in Aphasia Recovery