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ClinicalTrials.gov public records Last synced Nov 10, 2026, 1:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1585–1608 of 1,665 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham (Control) Clear all

Conditions: Gluteus Medius Muscle Strength, Lateral Hip Pain, Greater Trochanter Pain Syndrome, Gluteus Medius Tendinopathy, Gluteus Minimus Tendinopathy
Interventions: Unilateral neutral shoe insert, Bilateral Shoe Insert, Physical Therapy; Device · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Glendale, Arizona

Conditions: Onychomycosis
Interventions: HTU-520 Patch, Placebo Patch; Drug · Other
Lead sponsor: Hisamitsu Pharmaceutical Co., Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 37
States / cities: Birmingham, Alabama • Glendale, Arizona • Tucson, Arizona + 30 more

Conditions: Sleep, Sleep Disorders Not Due to A Substance or Known Physiological Condition
Interventions: Powersleep, Sham Powersleep; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 50 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 4
States / cities: Atlanta, Georgia • Chesterfield, Missouri • St Louis, Missouri + 1 more

Conditions: Asthma, Allergic Rhinitis, Allergic Conjunctivitis
Interventions: Active air purifier in respiratory allergies/asthma, Sham air purifier; Other
Lead sponsor: Molekule; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Mild Cognitive Impairment (MCI), Mild Neurocognitive Disorder, Neurocognitive Disorders, Cognitive Dysfunction, Cognition Disorders
Interventions: Accelerated iTBS, Computerized Cognitive Training, Sham Computerized Cognitive Training; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 60 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Phantom Limb Pain
Interventions: Farabloc Limb Cover, Sham Limb Cover; Device
Lead sponsor: Southern California Institute for Research and Education; Other
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Long Beach, California

Conditions: Epilepsy
Interventions: Temporal Interference Electrical Stimulation; Device
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Pain
Interventions: Paracervical Nerve Block, Sham Paracervical Block; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 14 Years to 22 Years · Female only
Enrollment: 98 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 3
States / cities: Philadelphia, Pennsylvania

Conditions: Huntington's Disease
Interventions: intra-striatal rAAV5-miHTT, Imitation (sham) surgery; Genetic · Other
Lead sponsor: UniQure Biopharma B.V.; Industry
Eligibility: 25 Years to 65 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2029
U.S. locations: 12
States / cities: Birmingham, Alabama • Tucson, Arizona • San Francisco, California + 9 more

Conditions: Diabetic Peripheral Neuropathy
Interventions: Active Provant Therapy System, Inactive (sham) Provant Therapy System; Device
Lead sponsor: Regenesis Biomedical, Inc.; Industry
Eligibility: 22 Years to 80 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Hemorrhage, Surgical, Hemorrhage Postoperative, Blood Loss, Surgical, Blood Loss, Postoperative
Interventions: Sham comparator, DrugSorb-ATR system; Device
Lead sponsor: CytoSorbents, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 27
States / cities: Sacramento, California • Denver, Colorado • New Haven, Connecticut + 22 more

Conditions: Nicotine Dependence
Interventions: one time exposure to e-cig with nicotine, one time exposure to e-cig without nicotine, one time exposure to empty e-cig; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 45 Years
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Limb Pain, Phantom
Interventions: Lidocaine, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Mankato, Minnesota

Conditions: Diabetic Macular Edema (DME)
Interventions: AKB-9778, ranibizumab, Placebo, Sham; Drug
Lead sponsor: Aerpio Therapeutics; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 39
States / cities: Pheonix, Arizona • Tucson, Arizona • Arcadia, California + 35 more

Conditions: Allergic, Inflammatory
Interventions: Environmental Exposures, Control Exposures; Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Head Injury Trauma
Interventions: osteopathic manipulative medicine, The sham light touch will be performed by an investigator not trained in bodywork or a first--year osteopathic medical student.; Procedure
Lead sponsor: New York Institute of Technology; Other
Eligibility: 18 Years to 50 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Greenvale, New York

Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: Hyperbaric oxygen, Hyperbaric chamber; Drug · Device
Lead sponsor: National Baromedical Services; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 4
States / cities: Rochester, Minnesota • Lebanon, New Hampshire • Columbia, South Carolina + 1 more

Conditions: Constipation
Interventions: Vibrant capsule, Sham capsule; Device
Lead sponsor: Vibrant Ltd.; Industry
Eligibility: 22 Years and older
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Guntersville, Alabama • Miami, Florida

Conditions: Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (AMD)
Interventions: BS01, Sham procedure control; Biological · Other
Lead sponsor: Bionic Sight LLC; Industry
Eligibility: 50 Years to 85 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Edison, New Jersey

Conditions: Depression, Major Depressive Disorder
Interventions: Transcranial Light Therapy, Sham Transcranial Light Therapy; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Boston, Massachusetts • Orangeburg, New York

Conditions: Visual Impairment, Cognitive Change
Interventions: computerized training; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 89 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Chronic Low Back Pain
Interventions: Spinal Manipulation, Detuned Ultrasound; Procedure
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 65 Years and older
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Buffalo, New York • Canandaigua, New York

Conditions: Multiple Sclerosis
Interventions: Dry Needling, Sham Dry Needling; Procedure
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Bipolar Disorder
Interventions: tACS brain stimulation treatment, Sham stimulation treatment; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Search by objective public record fields.

The Utilization of a Shoe Insert on Individuals With Unilateral Greater Trochanteric Pain Syndrome on Single Leg Stance, Biomechanics, and Pain Intensity

Safety & Efficacy Study of HTU-520 in the Treatment of Distal Subungual Onychomycosis of the Toenail

Feasibility, Effectiveness and Efficacy of the PowerSleep Device

Molekule for Allergic Rhinitis/Asthma

Brain Stimulation and Cognitive Training for MCI

Controlled Study of Farabloc for Chronic Phantom Limb Pain Among Veteran Amputees

Cognitive and Electrophysiological Assessment of Non-Invasive Temporally-Interfering Electric Fields Stimulation (TIEFS)

Study of Pain Control With Hormonal IUS Insertion

Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Disease

Study of PEMF to Evaluate VPT and Thermal Sensory in Subjects With Diabetic Peripheral Neuropathy

Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)

E-cigarettes and Blood Vessel Function

A Study of Contralateral Limb Block

The TIME-2 Study: A Phase 2 Study of AKB-9778, a Novel Tie-2 Activator, in Patients With Diabetic Macular Edema

THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial Toxins

Osteopathic Manipulative Treatment RCT and Computational Modeling for Head Injuries in Mixed Martial Artists

Hyperbaric Radiation Sensitization of Head and Neck Cancers

A Study to Assess the Efficacy and Safety of the Vibrant Capsule Administered 5 Times Per Week

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD

Transcranial Laser Therapy, Continuous and Pulsed Light, for Major Depressive Disorder (ELATED-3)

Peripheral Vision Training Study

Chiropractic Management of Chronic Lower Back Pain in Older Adults

Dry Needling in Multiple Sclerosis

Bipolar Transcranial Alternating Current Stimulation (tACS)