Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:20 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 147 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham Air Clear all

Conditions: Respiratory Distress Syndrome of Prematurity (Surfactant Dysfunction), Bronchopulmonary Dysplasia
Interventions: Infasurf (ONY Inc.), Sham; Drug
Lead sponsor: Roberta Ballard; Other
Eligibility: 7 Days to 14 Days
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 9
States / cities: Berkeley, California • Oakland, California • San Francisco, California + 5 more

Conditions: Cardiovascular Effects
Interventions: Diesel Exhaust, Filtered Air, Terazosin, placebo; Other · Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 49 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Spinal Cord Injuries (SCI)
Interventions: Augmented Acute Intermittent Hypoxia (aAIH), Acute Intermittent Hypercapnic-Hypoxia (AIHH), Sham AIH; Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 70 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Congenital Heart Disease, Hypoplastic Left Heart Syndrome
Interventions: Curosurf, Sham; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 1 Day to 12 Weeks
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder, Methamphetamine-dependence
Interventions: EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks, CBOT Sham; Combination Product
Lead sponsor: Evon Medics LLC; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Rockville, Maryland

Conditions: Sleep Apnea, Glucose Metabolism Disorders
Interventions: Positive Airway Pressure, Supplemental Oxygen, Sham; Procedure
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 30 Years to 70 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2028
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: ALS
Interventions: Consume 20mg of istradefylline, Low Oxygen therapy, Placebo counterpart to the istradefylline drug, SHAM counterpart to low oxygen therapy.; Drug · Other
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 2
States / cities: Gainesville, Florida • Jacksonville, Florida

Conditions: Healthy Brain Perfusion
Interventions: Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia; Other
Lead sponsor: Northwestern University; Other
Eligibility: 21 Years to 50 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cervical Spinal Cord Injury
Interventions: PCMS + Contralateral Motor Training, PCMS + Rest, Sham PCMS + Contralateral Motor Training; Device
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Depression, Anhedonia
Interventions: Low Intensity Focused Ultrasound Pulsation (LIFUP); Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Intermittent Hypoxia, Normoxia
Interventions: Intermittent Hypoxia, Normoxia (sham); Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 80 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Optic Neuropathy, Glaucoma
Interventions: Hyperbaric Oxygen, Sham Hyperbaric Oxygen; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Stroke, Sleep Apnea, Obstructive
Interventions: Auto-titrating CPAP, Sham-CPAP; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Ulcerative Colitis
Interventions: Hyperbaric Oxygen Therapy, Sham Hyperbaric Air; Device · Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 13
States / cities: Birmingham, Alabama • Los Angeles, California • Miami, Florida + 9 more

Conditions: Obstructive Sleep Apnea
Interventions: Oral appliance, Oxygen, Oral appliance plus oxygen, No treatment; Device · Drug · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 79 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Migraine With or Without Aura, Migraine, Migraine Headache
Interventions: Mi-Helper; Device
Lead sponsor: Mi-Helper, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Indian Harbour Beach, Florida

Conditions: Spinal Cord Injuries
Interventions: Daily acute intermittent hypoxia, Room air (SHAM), Walking + tSTIM, Walking + Sham transcutaneous spinal stimulation (tSHAM); Other
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Chicago, Illinois • Cambridge, Massachusetts

Conditions: Surgery
Interventions: Air Barrier System Device, Sham Air Barrier System device; Device
Lead sponsor: Nimbic Systems, LLC; Industry
Eligibility: Not listed
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Type 2 Diabetes
Interventions: Heat therapy, Sham; Device
Lead sponsor: Purdue University; Other
Eligibility: 55 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: West Lafayette, Indiana

Conditions: Bronchopulmonary Dysplasia
Interventions: Infasurf, Pulmicort, Sham; Drug · Other
Lead sponsor: East Carolina University; Other
Eligibility: 24 Weeks to 28 Weeks
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Greenville, North Carolina

Conditions: Anesthesia Airway Management, Respiratory Complications
Interventions: Inflated Cuff Extubation, Deflated Cuff Extubation; Procedure
Lead sponsor: Naval Medical Center Camp Lejeune; Federal
Eligibility: 18 Years to 50 Years
Enrollment: 88 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Marine Corps Base Camp Lejeune, North Carolina

Conditions: Obsessive-Compulsive Disorder
Interventions: Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex, Exposure with Response Prevention, Transcranial Magnetic Stimulation: Sham, Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area; Device · Behavioral
Lead sponsor: Bradley Hospital; Other
Eligibility: 12 Years to 21 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Riverside, Rhode Island

Conditions: Traumatic Brain Injury With Brief Loss of Consciousness, Post-Concussion Syndrome
Interventions: Hyperbaric oxygen (HBO2) at 1.5 atms, Sham control 1.2 atms; Drug
Lead sponsor: U.S. Army Medical Research and Development Command; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 5
States / cities: Colorado Springs, Colorado • Fort Carson, Colorado • Jacksonville, North Carolina + 2 more

Conditions: Overactive Bladder, Neurogenic Bladder, Urge Incontinence, Pain, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic, Urinary Bladder Neurogenesis, Urinary Incontinence, Urge, Pelvic Floor Disorders
Interventions: Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask; Drug · Other
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years and older · Female only
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 2
States / cities: Cincinnati, Ohio

Search by objective public record fields.

Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide

Diesel Exhaust and Vascular Function

Hypoxia Pathways for Early Recovery After Spinal Cord Injury

Cold Heart Study: A Randomized Pilot Trial of Surfactant Therapy

Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders

Obstructive Sleep Apnea and Glucose Metabolism

Adenosine 2A Receptor Antagonism and AIH in ALS

Improving Human Cerebrovascular Function Using Acute Intermittent Hypoxia

Rebuilding Inter-limb Transfer in Cervical SCI

Investigating LIFUP in Anhedonic Depression

Intermittent Hypoxia and Balance Control

Hyperbaric Oxygen Therapy for Optic Neuropathies

Stroke and CPAP Outcome Study: A Sham-controlled Trial of CPAP Among Stroke Rehabilitation Patients

Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

Cooling to Alleviate Migraine #3

Combination Therapy to Improve SCI Recovery.

Device to Reduce Surgery Site Contamination

Heat Therapy in Type 2 Diabetes

Pilot Study of Topical Steroid for Prevention of Chronic Lung Disease in Extremely Premature Infants.

Deflated and Inflated Cuff Endotracheal Extubations

TMS + Exposure Therapy for Pediatric OCD

mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms

A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections