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ClinicalTrials.gov public records Last synced Oct 19, 2026, 5:01 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 263 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Pressure Clear all
Completed Not applicable Interventional

Ischemic Preconditioning as an Intervention to Improve Stroke Rehabilitation - Froedtert

NCT03023150
View directory record Official record
Conditions
Stroke Rehabilitation, Ischemic Preconditioning, Physical and Rehabilitation Medicine
Interventions
Ischemic Preconditioning, Sham
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
40 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 25, 2023 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Vascular Impairment in Type II Diabetes Mellitus With Co-morbid Obstructive Sleep Apnea

NCT01629862
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Diabetes Mellitus
Interventions
Continuous positive airway pressure, Sham continuous positive airway pressure
Device
Lead sponsor
Sanjay R Patel
Other
Eligibility
18 Years to 70 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 28, 2019 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Ischemic Conditioning as an Intervention to Improve Motor Function in Chronic Stroke

NCT03095755
View directory record Official record
Conditions
Stroke
Interventions
Ischemic Conditioning, Sham
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 19, 2026, 5:01 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

NCT05731986
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases, Trauma, Nervous System, Nervous System Diseases, Central Nervous System Diseases, Hypotension, Orthostatic Hypotension, Cardiovascular Diseases, Acute Spinal Cord Injury, Blood Pressure
Interventions
Orthostatic challenge, Biostim-5 transcutaneous spinal stimulation - Mapping, Biostim-5 transcutaneous spinal stimulation - "Optimal" testing, Biostim-5 transcutaneous spinal stimulation - "Sham" testing
Diagnostic Test · Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Iron Reduction for the Treatment of Diabetes and Nonalcoholic Fatty Liver Disease

NCT03696797
View directory record Official record
Conditions
Iron, Diabetes, Nonalcoholic Fatty Liver
Interventions
Blood Donation, Sham Blood Donation
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years to 75 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Intervention for Pregnancy Related Pain

NCT03440073
View directory record Official record
Conditions
Other Specified Pregnancy-Related Conditions
Interventions
Mulligan Concept Intervention, Sham Mulligan Concept Treatment
Other
Lead sponsor
University of Idaho
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Moscow, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 23, 2018 · Synced Oct 19, 2026, 5:01 PM EDT
Recruiting Not applicable Interventional

Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries

NCT05351827
View directory record Official record
Conditions
Spinal Cord Injuries, Autonomic Dysreflexia
Interventions
Mild Intermittent Hypoxia, Sham
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Foot Reflexology in Ocular Hypertensive and Glaucoma Patients

NCT04695314
View directory record Official record
Conditions
Ocular Hypertension, Glaucoma
Interventions
Massage, Experimental insert, Sham insert
Device · Procedure
Lead sponsor
Temple University
Other
Eligibility
30 Years to 90 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2021 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Phase 4 Interventional

One vs. Three Hyperbaric Oxygen Treatments for Acute Carbon Monoxide Poisoning

NCT00465855
View directory record Official record
Conditions
Carbon Monoxide Poisoning
Interventions
Hyperbaric Oxygen (HBO2) - 3 sessions, Hyperbaric Oxygen (HBO2) - 1 session
Combination Product
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 79 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 12, 2021 · Synced Oct 19, 2026, 5:01 PM EDT
Recruiting Not applicable Interventional

PEP Buddy in Pulmonary Rehabilitation

NCT07404826
View directory record Official record
Conditions
COPD
Interventions
PEP Buddy, PEP Buddy Sham
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 89 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Cincinnati, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Vibratory PEP Device and Hospital Length of Stay for Acute Exacerbation of COPD

NCT03094806
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Acapella Vibratory PEP Therapy Device plus usual care, Sham Acapella Vibratory PEP Device plus usual care
Device
Lead sponsor
New York Presbyterian Brooklyn Methodist Hospital
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Oct 19, 2026, 5:01 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

fMRI in Postural Tachycardia Syndrome

NCT04137757
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Lower Body Negative Pressure, Sham Pressure
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults

NCT03512028
View directory record Official record
Conditions
Healthy, Young Adults
Interventions
RLIC, Sham conditioning, Muscle strength training, Driving training, Balance training
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALS

NCT03851302
View directory record Official record
Conditions
Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
Interventions
Active Remote Ischemic Conditioning, Sham Remote Ischemic Conditioning, Isometric hand exercise
Other
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 19, 2026, 5:01 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Acupressure in Patients With Sickle Cell Disease

NCT06511453
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Verum Acupressure (using AcuWand), Sham Acupressure (using AcuWand)
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Irvine, California • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke

NCT05906602
View directory record Official record
Conditions
Stroke
Interventions
Real Ischemic Conditioning, Sham Ischemic Conditioning
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury

NCT03236441
View directory record Official record
Conditions
Contrast-induced Acute Kidney Injury
Interventions
RIPC, Sham-RIPC
Device
Lead sponsor
Oladipupo Olafiranye, MD, MS
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Effects of Continuous Positive Airway Pressure (CPAP) Treatment on Glucose Control in Patients With Type 2 Diabetes

NCT01136785
View directory record Official record
Conditions
Obstructive Sleep Apnea, Type 2 Diabetes
Interventions
active CPAP Therapy, sham CPAP therapy
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Osteopathic Manipulative Therapy on Hip Range of Motion

NCT06644989
View directory record Official record
Conditions
Runners
Interventions
Spencer Technique, Sham (No Treatment)
Procedure · Other
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Acupressure for Fatigue in Ovarian Cancer Survivors

NCT03763838
View directory record Official record
Conditions
Fatigue, Ovarian Cancer
Interventions
Acupressure, Sham acupressure, Standard of Care
Other
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
21 Years and older · Female only
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 19, 2026, 5:01 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Diesel Exhaust and Vascular Function

NCT01508637
View directory record Official record
Conditions
Cardiovascular Effects
Interventions
Diesel Exhaust, Filtered Air, Terazosin, placebo
Other · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 49 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Oct 19, 2026, 5:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Acupressure for Fatigue in Systemic Lupus Erythematosus

NCT03200548
View directory record Official record
Conditions
Fatigue, Lupus Erythematosus, Systemic, Pain, Chronic, Quality of Life, Sleep
Interventions
Relaxing acupressure plus usual care, Usual care, Stimulating acupressure plus usual care, Sham acupressure plus usual care
Behavioral
Lead sponsor
Suzanna Zick
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 12, 2023 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Tolerability Study of the Application of a 3M Microstructure Transdermal System

NCT01257763
View directory record Official record
Conditions
Healthy
Interventions
Transdermal Microchannel Skin System, Sham device
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 74 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Oct 19, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Use of Novel Sinusonic Device for Prevention of Community Acquired Upper Respiratory Infection (URI)

NCT04468204
View directory record Official record
Conditions
Upper Respiratory Infection
Interventions
SinuSonic Device, Sham SinuSonic Device
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 20, 2022 · Synced Oct 19, 2026, 5:01 PM EDT