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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:03 AM EDT

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Showing 169–192 of 283 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Test Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Sacral Savers: Study of Prevention and Enhanced Healing of Sacral and Trochenteric Ulcers

NCT03211910
View directory record Official record
Conditions
Healing Ulcer
Interventions
SacralSaver, Standard Care of Treatment
Device · Other
Lead sponsor
Richmond University Medical Center
Other
Eligibility
50 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Phase 3 Interventional Results available

Closed Loop Vagal Nerve Stimulation for Patients With Posttraumatic Stress Disorder

NCT02992899
View directory record Official record
Conditions
PostTraumatic Stress Disorder
Interventions
GammaCore/electroCore non-invasive VNS device, Sham gammaCore/electroCore, O-15 water
Device · Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 14, 2021 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

Sub-Acute Stroke Rehabilitation With AMES

NCT00609115
View directory record Official record
Conditions
Cerebrovascular Stroke
Interventions
AMES device (test), AMES device (sham), AMES device (crossover)
Device
Lead sponsor
AMES Technology
Industry
Eligibility
18 Years to 80 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
5
States / cities
Rancho Mirage, California • San Francisco, California • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation Effects on Pain Perception

NCT01861574
View directory record Official record
Conditions
Gastric Bypass Surgery Pain Management
Interventions
Real TMS 45 min, Sham TMS 45 min, Real TMS 4 Hours, Sham TMS 4 Hours
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessing Effects of a Denture Gel on Gum Abrasions

NCT04913636
View directory record Official record
Conditions
Gum Injury
Interventions
Treatment Gel, Sham Control
Device · Other
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 22, 2026, 4:03 AM EDT
Recruiting Not applicable Interventional

Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC

NCT04217603
View directory record Official record
Conditions
Tracheobronchomalacia, Excessive Dynamic Airway Collapse
Interventions
Continuous positive airway pressure (CPAP) device, Sham-continuous positive airway pressure (CPAP) device
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional

The Effects of Journaling on Health-Related Mood and Clinical Outcomes in Post-MI Patients

NCT02481544
View directory record Official record
Conditions
Myocardial Infarction, Psychosocial Factors
Interventions
Gratitude Journaling Plus SOC, Memorable Events Journaling Plus SOC
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
35 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Oct 22, 2026, 4:03 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Determine the Effect on Cognitive Impairment Measures by Providing Hearing-Assistance to Skilled Nursing Facility Residents

NCT03338751
View directory record Official record
Conditions
Hearing Impairment
Interventions
cognitive testing with HAD (PockeTalker) First, Cognitive testing without HAD First
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 9, 2017 · Synced Oct 22, 2026, 4:03 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Heating Pad for in Office Cystoscopy and Urodynamic Testing

NCT05981794
View directory record Official record
Conditions
Anxiety, Pain, Distress, Emotional
Interventions
Electrical heating pad, Sham heating pad
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 23, 2025 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus

NCT03442751
View directory record Official record
Conditions
Progressive Keratoconus
Interventions
Test Article A, Test Article B, Placebo, KXL medical device system
Drug · Device
Lead sponsor
Glaukos Corporation
Industry
Eligibility
12 Years to 55 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Oct 22, 2026, 4:03 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

The Effect of Transcutaneous Magnetic Stimulation on Acute Pain.

NCT03777137
View directory record Official record
Conditions
Pain Perception
Interventions
TMS (Rapid2, Magstim Corp)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 14, 2021 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

BabyStrong Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Paired Bottle Feeding to Improve Oral Feeding

NCT04849507
View directory record Official record
Conditions
Infant Feeding Problems, taVNS
Interventions
transcutaneous auricular vagus nerve stimulation, Sham transcutaneous auricular vagus nerve stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
2 Weeks to 5 Months
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 22, 2026, 4:03 AM EDT
Active, not recruiting Not applicable Interventional

Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)

NCT05172271
View directory record Official record
Conditions
Major Depressive Disorder, Bipolar Disorder, Unipolar Major Depression
Interventions
MagPro TMS Stimulator and coil, Thymatron(R) System IV, Magnetic Resonance Imaging Scanner, ECT device without stimulation
Device · Other
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
25 Years to 64 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 22, 2026, 4:03 AM EDT
Terminated Not applicable Interventional Results available

Galvanic Vestibular Stimulation and Motor Training in Traumatic Brain Injury Survivors

NCT01749800
View directory record Official record
Conditions
TBI, Attention Deficits, Motor Impairments
Interventions
GVS, Sham GVS, Armeo Spring
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional

RNS System NAUTILUS Study

NCT05147571
View directory record Official record
Conditions
Epilepsy, Idiopathic Generalized Epilepsy, Generalized Tonic Clonic Seizure
Interventions
Responsive stimulation, Sham stimulation
Device
Lead sponsor
NeuroPace
Industry
Eligibility
12 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
23
States / cities
Birmingham, Alabama • Phoenix, Arizona • Aurora, Colorado + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 22, 2026, 4:03 AM EDT
Recruiting Not applicable Interventional

Ultrasound Neuromodulation in Essential Tremor

NCT06610877
View directory record Official record
Conditions
Essential Tremor, Neuromodulation
Interventions
Focused Ultrasound Neuromodulation - Sham Control, Focused ultrasound neuromodulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

INSIGHT, A Comprehensive, Multidisciplinary Brain Training System

NCT02780739
View directory record Official record
Conditions
Cognitive Ability, General
Interventions
Cognitive Training - 48 sessions, Fitness, Active Control, active tDCS, sham tDCS, Cognitive Training - 20 sessions
Behavioral · Device
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 44 Years
Enrollment
521 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 23, 2016 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

Conservative Treatment of Patients With Temporomandibular Disorders

NCT01021306
View directory record Official record
Conditions
Temporomandibular Disorders
Interventions
Chiropractic w/Activator & Self Care, Dental Care & Self Care, Sham AMCT, Self-Care Only Group
Device · Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
21 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
3
States / cities
Coralville, Iowa • Davenport, Iowa • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Oct 22, 2026, 4:03 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma

NCT04196933
View directory record Official record
Conditions
Migraine, Vestibular Migraine, Vestibular Schwannoma, Motion Sickness, Dizziness, Vestibular Disorder
Interventions
Temporal Binding Adaptation - PSS training, Temporal Binding Adaptation - PSS adaptation with VI stimulation, Chronic Motion-modulated Stimulation
Behavioral
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
8 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 22, 2026, 4:03 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Assessment of Human Sleep and Its Functions

NCT07211646
View directory record Official record
Conditions
Insomnia
Interventions
sham tES, Fixed tES, Personalized tES
Other
Lead sponsor
StimScience Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Phase 1 Interventional Results available

Transcranial Magnetic Stimulation to Improve Speech in Aphasia

NCT00608582
View directory record Official record
Conditions
Aphasia, Cerebrovascular Stroke
Interventions
Transcranial Magnetic Stimulation, Repetitive
Device
Lead sponsor
Boston University
Other
Eligibility
45 Years to 80 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2013
U.S. locations
3
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Thoracic Spine Manipulation on Peripheral Neurodynamic Mobility

NCT02842918
View directory record Official record
Conditions
Musculoskeletal Manipulations
Interventions
Spinal Manual Therapy, Spinal Range of Motion
Procedure
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 70 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 22, 2026, 4:03 AM EDT
Recruiting Not applicable Interventional

Insula Neuromodulation for Chronic Neuropathic Pain

NCT05404581
View directory record Official record
Conditions
Neuropathic Pain, Chronic Pain
Interventions
neuromodulation
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 22, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

Reversing Synchronized Brain Circuits With Targeted Auditory-Somatosensory Stimulation to Treat Phantom Percepts

NCT03621735
View directory record Official record
Conditions
Tinnitus
Interventions
Burst-SCS/sham SCS, Sham SCS/Burst-SCS
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 22, 2026, 4:03 AM EDT