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ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 313–336 of 1,656 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham control Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls

NCT07680114
View directory record Official record
Conditions
Schizophrenia
Interventions
TES-TI, Sham TES-TI
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcutaneous Electroacupuncture for Gastric Complications of Scleroderma

NCT03294616
View directory record Official record
Conditions
Scleroderma, Gastroparesis
Interventions
transcutaneous electroacupuncture
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2019 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Not applicable Interventional Results available

Feasibility Study to Test Clinical Efficacy of Low Energy AC Magnetic Field to Treat Major Depression

NCT01683019
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
NeoSync EEG Synchronization Therapy, Sham NeoSync EEG Synchronization Therapy
Device
Lead sponsor
Wave Neuroscience
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2018 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Phase 2 Interventional

Efficacy of Inhaled Cannabis for Acute Migraine Treatment

NCT04360044
View directory record Official record
Conditions
Migraine, Cannabis, THC, CBD
Interventions
THC ~5%, CBD ~12%, THC ~5% and CBD ~12%, Sham Cannabis
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Oct 22, 2026, 1:05 AM EDT
Recruiting Not applicable Interventional

External Therapy for Tinnitus Management

NCT07017998
View directory record Official record
Conditions
Tinnitus, Tinnitus, Subjective
Interventions
Cold pack-delivered mild therapeutic hypothermia, Sham (No Treatment)
Device
Lead sponsor
Restorear Devices LLC
Industry
Eligibility
18 Years to 55 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Not applicable Interventional Results available

Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)

NCT04976530
View directory record Official record
Conditions
Hemorrhage, Surgical, Blood Loss, Surgical, Blood Loss, Postoperative, Hemorrhage Postoperative
Interventions
DrugSorb-ATR system, Sham comparator
Device
Lead sponsor
CytoSorbents, Inc
Industry
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
22
States / cities
Sacramento, California • New Haven, Connecticut • Washington D.C., District of Columbia + 18 more
Source: ClinicalTrials.gov public record
Updated Apr 11, 2025 · Synced Oct 22, 2026, 1:05 AM EDT
Active, not recruiting Not applicable Interventional

At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study]

NCT07163221
View directory record Official record
Conditions
Rheumatoid Arthritis (RA)
Interventions
Non-invasive ultrasound stimulation of the spleen - Treatment Setting 1, Non-invasive ultrasound stimulation of the spleen - Treatment Setting 2, Sham ultrasound stimulation (control), Conventional Synthetic DMARD
Device · Drug
Lead sponsor
SecondWave Systems Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
5
States / cities
Glendale, Arizona • Covina, California • Temecula, California + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Phase 3 Interventional

A Study of SI-6603 in Patients With Lumbar Disc Herniation

NCT01941563
View directory record Official record
Conditions
Intervertebral Disc Disease, Lumbar Disc Disease
Interventions
Condoliase, placebo
Drug
Lead sponsor
Seikagaku Corporation
Industry
Eligibility
30 Years to 70 Years
Enrollment
385 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
32
States / cities
Phoenix, Arizona • Gold River, California • Laguna Hills, California + 29 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 22, 2026, 1:05 AM EDT
Terminated Not applicable Interventional Results available

Effects of Neuro-Stim System on Pain, Sleep, and Opioid Use

NCT02673684
View directory record Official record
Conditions
Pain (Visceral, Somatic, or Neuropathic)
Interventions
Experimental NSS, Sham NSS
Device
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Not applicable Interventional

Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation

NCT04502758
View directory record Official record
Conditions
Suicidal Ideation, Major Depressive Disorder
Interventions
MagVenture TMS Therapy System w/Theta Burst Stimulation, Sham MagVenture TMS Therapy System w/Theta Burst Stimulation
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Phase 1Phase 2 Interventional Results available

50 Hz Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Parkinson's Disease

NCT00977184
View directory record Official record
Conditions
Parkinson Disease
Interventions
50 HZ Repetitive TMS, Sham rTMS
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
40 Years to 80 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 27, 2012 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Phase 2 Interventional

A Study of Safety, Tolerability, and Evidence of Activity of FCFD4514S Administered Monthly or Every Other Month to Patients With Geographic Atrophy

NCT01229215
View directory record Official record
Conditions
Geographic Atrophy
Interventions
FCFD4514S, sham
Drug
Lead sponsor
Genentech, Inc.
Industry
Eligibility
60 Years to 89 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
30
States / cities
Tucson, Arizona • Beverly Hills, California • San Francisco, California + 26 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Oct 22, 2026, 1:05 AM EDT
Terminated Not applicable Interventional Results available

Migraine Treatment With Nerivio Migra Neurostimulation Device

NCT03076515
View directory record Official record
Conditions
Acute Migraine
Interventions
Nerivio Migra neurostimulation, Sham Nerivio Migra
Device
Lead sponsor
Theranica
Industry
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Albany, New York • Hartford, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Oct 22, 2026, 1:05 AM EDT
Active, not recruiting Not applicable Interventional

Daily Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease

NCT04055376
View directory record Official record
Conditions
Alzheimer Disease, Alzheimer Dementia
Interventions
GENUS device (Active Settings), GENUS device (Sham Settings)
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
50 Years to 100 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Not applicable Interventional

Metabolic Health in Individuals With Spinal Cord Injury (SCI)

NCT03204240
View directory record Official record
Conditions
Spinal Cord Injuries, Skeletal Muscle Atrophy, Metabolic Disease
Interventions
Neuromuscular electrical stimulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Phase 3 Interventional Results available

A Study of Ustekinumab to Evaluate a "Subject-tailored" Maintenance Dosing Approach in Subjects With Moderate-to-Severe Plaque Psoriasis

NCT01550744
View directory record Official record
Conditions
Psoriasis
Interventions
Ustekinumab 45 mg, Ustekinumab 90 mg, Placebo
Drug
Lead sponsor
Janssen Biotech, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
478 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
40
States / cities
Birmingham, Alabama • Bakersfield, California • Irvine, California + 37 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Oct 22, 2026, 1:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Causal Role of the Aperiodic Signal for Working Memory

NCT06126809
View directory record Official record
Conditions
Executive Dysfunction
Interventions
Steep-tRAS, Flat-tRAS, Sham-tRAS
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Recruiting Not applicable Interventional

Advancing Alzheimer's Care: Home-based tDCS for Affective Symptoms

NCT06801639
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Transcranial direct current stimulation (tDCS), Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
60 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Explosive Synchronization of Brain Network Activity in Chronic Pain

NCT04606095
View directory record Official record
Conditions
Fibromyalgia, Healthy Volunteers
Interventions
EEG, Neuroimaging EEG/fMRI (Aim 1), HD-tDCS treatments, Sham HD-tDCS treatments, Neuroimaging EEG/fMRI (Aim 3)
Diagnostic Test · Device
Lead sponsor
University of Michigan
Other
Eligibility
19 Years to 74 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Recruiting Not applicable Interventional

Radio- KO Radiotherapy for Knee Osteoarthritis Clinical Trial

NCT06887829
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Low dose radiotherapy, Sham comparator
Radiation · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years to 100 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Not applicable Interventional

Dry Needling for Sub Acromial Pain Syndrome

NCT03442894
View directory record Official record
Conditions
Subacromial Impingement Syndrome
Interventions
Standard Physical Therapy Treatment, Dry Needling, Sham Dry Needling
Procedure
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 65 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 22, 2026, 1:05 AM EDT
Recruiting Phase 2 Interventional

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

NCT06595953
View directory record Official record
Conditions
Psychiatric Disorders, Anxiety Disorders
Interventions
Gaze-Contingent Music Reward Therapy
Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
8 Years to 17 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 22, 2026, 1:05 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Investigation and Modulation of the Mu-Opioid Mechanisms in Migraine (in Vivo)

NCT02964741
View directory record Official record
Conditions
Migraine
Interventions
Active Comparator, Sham Comparator
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Oct 22, 2026, 1:05 AM EDT
Completed Phase 3 Interventional Results available

Greater Occipital Nerve Block With Bupivacaine for Acute Migraine

NCT02665273
View directory record Official record
Conditions
Migraine
Interventions
Greater occipital nerve block, Bupivacaine
Procedure · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Oct 22, 2026, 1:05 AM EDT