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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:15 AM EST

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Showing 1–24 of 40 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham transcutaneous spinal cord stimulation Clear all
Recruiting Not applicable Interventional

Low Oxygen Therapy to Enhance Walking Recovery After SCI.

NCT06521723
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Daily acute intermittent hypoxia, Walking + tSTIM
Other · Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Jacksonville, Florida • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Recruiting Not applicable Interventional

Combining Spinal Cord Transcutaneous Stimulation and Activity-based Training in Inpatient Rehabilitation to Facilitate Upper Limb Function of Individuals with Acute to Subacute Cervical Spinal Cord Injury

NCT06773286
View directory record Official record
Conditions
Spinal Cord Injury Cervical
Interventions
Active Stimulation, Sham, Training only
Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Nov 15, 2026, 8:15 AM EST
Withdrawn Not applicable Interventional

Transcutaneous Intercostal Nerve Stimulation in Spinal Cord Injury

NCT04506099
View directory record Official record
Conditions
Neuropathic Pain, SCI - Spinal Cord Injury
Interventions
TINS Active protocol, Sham protocol
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 22, 2021 · Synced Nov 15, 2026, 8:15 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation for Metabolic Dysfunction

NCT07597161
View directory record Official record
Conditions
Spinal Cord Injuries (SCI), Prediabetes / Type 2 Diabetes
Interventions
Transcutaneous Spinal Cord Stimulation (tSCS), Sham transcutaneous spinal cord stimulation (tSCS)
Device
Lead sponsor
Rahul Sachdeva
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 29, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Completed Not applicable Interventional

Metabolic Health in Individuals With Spinal Cord Injury (SCI)

NCT03204240
View directory record Official record
Conditions
Spinal Cord Injuries, Skeletal Muscle Atrophy, Metabolic Disease
Interventions
Neuromuscular electrical stimulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Nov 15, 2026, 8:15 AM EST
Recruiting Not applicable Interventional

Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury

NCT06213012
View directory record Official record
Conditions
Spinal Cord Injuries, Neuromodulation
Interventions
Transcutaneous Spinal cord Stimulation, Epidural Spinal Stimulation (ESS)
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
22 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Recruiting Not applicable Interventional

Transcutaneous Spinal Cord Stimulation in Children With Incomplete Spinal Cord Injury

NCT06242873
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Gait training with/without TSCS
Other
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
3 Years to 16 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Recruiting Not applicable Interventional

Tibial Nerve Stimulation for Pediatric Spina Bifida Neurogenic Bladder

NCT07136688
View directory record Official record
Conditions
Neurogenic Bladder Due to Spina Bifida
Interventions
Stamobil electric stimulator, sham tTNS device
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
4 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Completed Not applicable Interventional Results available

Effects of Transcutaneous Spinal Direct Current Stimulation in Incomplete Spinal Cord Injury

NCT03249454
View directory record Official record
Conditions
Incomplete Spinal Cord Injury
Interventions
Anodal tsDCS, Cathodal tsDCS, Sham tsDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Nov 15, 2026, 8:15 AM EST
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation of the Cortex and Spinal Cord

NCT06586437
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Clinical Assessments, Brain-Spinal Cord fMRI, Hoffmann Reflex Assessments, MEG Imaging, Transcutaneous Current Stimulation
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
11 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boys Town, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Enrolling by invitation Not applicable Interventional

Non-invasive Spinal Stimulation for Gait in Genetic Spasticity

NCT07930481
View directory record Official record
Conditions
Hereditary Spastic Paraplegias, Spinocerebellar Ataxia, Spastic Ataxia
Interventions
Transcutaneous spinal cord stimulation, Sham transcutaneous spinal cord stimulation
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 12, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Not yet recruiting Not applicable Interventional

BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI)

NCT07659743
View directory record Official record
Conditions
Pain Management
Interventions
Active BreEStim Treatment, Sham BreEStim Treatment, The TENS Treatment
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
22 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Terminated Not applicable Interventional Results available

TENS Trial to Prevent Neuropathic Pain in SCI

NCT03267810
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
TENS, Sham TENS
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 14, 2023 · Synced Nov 15, 2026, 8:15 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers

Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury

NCT06101199
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Acute Intermittent Hypercapnic Hypoxia, Transcutaneous spinal cord stimulation, SHAM Acute Intermittent Hypercapnic Hypoxia, SHAM Transcutaneous spinal cord stimulation
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Nov 15, 2026, 8:15 AM EST
Not listed Early Phase 1 Interventional

Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury

NCT06274021
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic
Interventions
Transcutaneous spinal stimulation at 100 Hz, Transcutaneous spinal stimulation at 50 Hz, Transcutaneous spinal stimulation at 50 Hz and single dose of baclofen, Transcutaneous spinal stimulation at 50 Hz and single dose of tizanidine, Sham transcutaneous spinal stimulation
Device · Combination Product
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 1, 2024 · Synced Nov 15, 2026, 8:15 AM EST
Completed Not applicable Interventional Results available

Transcutaneous Electrical Nerve Stimulation for Pain Control During First-trimester Abortion

NCT05320432
View directory record Official record
Conditions
Abortion in First Trimester, Pain
Interventions
Transcutaneous electrical nerve stimulation (TENS), Sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Nov 15, 2026, 8:15 AM EST
Withdrawn Not applicable Interventional

The Biophysical Impact of Transcutaneous Spinal Cord Stimulation Within a Single Session

NCT03046875
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Transcutaneous Spinal Cord Stimulation, Sham stimulation
Other
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Nov 15, 2026, 8:15 AM EST
Completed Phase 1Phase 2 Interventional Results available

Spinal Cord Stimulation for the Treatment of Major Depressive Disorder

NCT03433339
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Active transcutaneous spinal direct current stimulation, Sham transcutaneous spinal direct current stimulation
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Nov 15, 2026, 8:15 AM EST
Completed Not applicable Interventional Results available

The Effects Upon the Bladder of Transcutaneous Tibial Nerve Stimulation in Acute Traumatic Spinal Cord Injury

NCT02573402
View directory record Official record
Conditions
Spinal Cord Injury, Neurogenic Bladder
Interventions
Transcutaneous Tibial Nerve Stimulation, Control
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Nov 15, 2026, 8:15 AM EST
Recruiting Not applicable Interventional

Combination Therapy to Improve SCI Recovery.

NCT05563103
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Daily acute intermittent hypoxia, Room air (SHAM), Walking + tSTIM, Walking + Sham transcutaneous spinal stimulation (tSHAM)
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Recruiting Not applicable Interventional

Locomotor Function Following Transcutaneous Electrical Spinal Cord Stimulation in Individuals With Hemiplegic Stroke

NCT05167786
View directory record Official record
Conditions
Stroke
Interventions
Noninvasive spinal stimulation with gait training, Conventional gait training, Exploratory Phase - Optimization of Gait Training and Spinal Stimulation
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

A Novel Repetitive Synchronized Associative Stimulation Neuromodulation Approach for Spinal Cord Injury Patients

NCT06494059
View directory record Official record
Conditions
SCI - Spinal Cord Injury
Interventions
Intermittent theta burst stimulation (iTBS), Functional electrical stimulation (FES), Transcutaneous spinal cord stimulation (TSCS), Sham Intermittent theta burst stimulation (iTBS)
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Completed Not applicable Interventional Results available

SCI Acute Intermittent Hypoxia and Non-Invasive Spinal Stimulation Combined With Gait Training

NCT03922802
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases
Interventions
Acute Intermittent Hypoxia + Non Invasive Spinal Cord Stimulation + Gait Training, Sham Acute Intermittent Hypoxia + Non Invasive Spinal Cord Stimulation + Gait Training, Sham Acute Intermittent Hypoxia + Sham Non Invasive Spinal Cord Stimulation + Gait Training
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Nov 15, 2026, 8:15 AM EST
Completed Not applicable Interventional

Transcutaneous Electrical Spinal Cord Stimulation for Lower Limbs

NCT01949285
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Transcutaneous Electrical Spinal Cord Stimulation
Device
Lead sponsor
NeuroEnabling Technologies, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Nov 15, 2026, 8:15 AM EST