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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:15 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Psychiatric Disorder
Interventions: Cranial Electrical Stimulation (CES), Discussion, Health and Wellness Coach, Informational Intervention, Sham Intervention; Procedure · Other · Behavioral
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 21 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Keratoconus
Interventions: Riboflavin-5-phosphate, Sham cross-linking; Drug
Lead sponsor: University at Buffalo; Other
Eligibility: 16 Years to 35 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Amherst, New York • Buffalo, New York

Conditions: Chronic Knee Pain
Interventions: Photobiomodulation therapy (PBM) device, Sham PBM device; Device
Lead sponsor: University of Florida; Other
Eligibility: 50 Years to 99 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Major Depressive Disorder (MDD)
Interventions: NeoSync EEG Synchronization Therapy, Sham NeoSync EEG Synchronization Therapy; Device
Lead sponsor: Wave Neuroscience; Industry
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Newport Beach, California

Conditions: Urinary Bladder, Overactive
Interventions: Treament, Sham Control; Device
Lead sponsor: FemPulse Corporation; Industry
Eligibility: 21 Years and older · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 2
States / cities: Woodbury, Minnesota • Seattle, Washington

Conditions: Aging, Depression, Cognitive Symptom
Interventions: Cognitive Training, tDCS (active stimulation), tDCS (sham stimulation); Behavioral · Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 60 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Insomnia, Primary
Interventions: LFMS - Active, LFMS - Sham; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Interventions: Active Virtual Reality, sham Virtual Reality, No Intervention, Naloxone, Saline, Natural history; Behavioral · Other · Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 88 Years
Enrollment: 259 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Atrial Fibrillation
Interventions: active tVNS, sham tVNS; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 80 Years
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Los Angeles, California • Oklahoma City, Oklahoma

Conditions: Disruptive Behavior, Attention-deficit Hyperactivity, Oppositional Defiant Disorder
Interventions: Garmin; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 3 Years to 99 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Blindness
Interventions: Electrotactile display (BrainPort), Vision-to-sound converter (AI Sight), Sham; Device
Lead sponsor: Stanford University; Other
Eligibility: 8 Years to 85 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 2
States / cities: Palo Alto, California • Stanford, California

Conditions: Pain, Postoperative
Interventions: Bridge device, Sham device; Device
Lead sponsor: Masimo Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Treatment Resistant Depression
Interventions: Sham-stimulation, Active-stimulation; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 22 Years to 70 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 26
States / cities: Birmingham, Alabama • Los Angeles, California • Sacramento, California + 19 more

Conditions: ALL, Hodgkin Lymphoma, Cancer, Survivorship
Interventions: Transcranial photobiomodulation (tPBM) - Mobile System; Device
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Alcohol Risk Behaviors
Interventions: Intermittent Theta Burst Stimulation, Continuous Theta Burst Stimulation, Sham Transcranial Magnetic Stimulation; Device
Lead sponsor: Michael J. Wesley, PhD; Other
Eligibility: 21 Years to 29 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Impulsivity, Compulsive Overeating, Obesity
Interventions: Device: Active Transcranial Direct Current Stimulation (tDCS) coupled with cognitive training, Device: Sham Transcranial Direct Current Stimulation (tDCS) coupled with cognitive training; Device
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Gastroparesis, Functional Dyspepsia, Vomiting Syndrome
Interventions: Temporary Gastric Electrical Stimulation; Device
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: Up to 21 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Chronic Pain, Osteoarthritis
Interventions: transcranial direct current stimulation (tDCS), transcranial ultrasound (TUS); Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 85 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Migraine
Interventions: Precision; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 179 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2018
U.S. locations: 15
States / cities: Denver, Colorado • Stamford, Connecticut • Augusta, Georgia + 11 more

Conditions: Stress Urinary Incontinence, Urge Incontinence, Urge and Stress, Overactive Bladder
Interventions: BTL EMSELLA Active treatment, BTL EMSELLA Sham Treatment; Device
Lead sponsor: Boston Urogynecology Associates; Other
Eligibility: 18 Years to 100 Years · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Body Contouring
Interventions: Erchonia ML Scanner (MLS), Sham device; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 3
States / cities: Palm Beach Gardens, Florida • Marion, Indiana • Bloomfield Hills, Michigan

Conditions: Ischemic Stroke
Interventions: Active Sphenopalatine Ganglion (SPG) Stimulation, Sham Sphenopalatine Ganglion (SPG) Stimulation; Device
Lead sponsor: BrainsGate; Industry
Eligibility: 40 Years to 85 Years
Enrollment: 1,078 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2018
U.S. locations: 7
States / cities: Sarasota, Florida • Winfield, Illinois • Greensboro, North Carolina + 3 more

Conditions: Male Infertility
Interventions: new device against ambient electromagnetic radiation, sham device against ambient electromagnetic radiation; Device
Lead sponsor: Waveguard GmbH; Industry
Eligibility: 18 Years to 50 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Heart Failure, Diastolic
Interventions: PowerBreathe (Breathing muscle training); Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Rochester, Minnesota

Search by objective public record fields.

Electrotherapy Stimulation Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers

Treatment of Keratoconus Using Collagen Cross-Linking

Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)

Feasibility Study to Test Clinical Efficacy of Low Energy AC Magnetic Field to Treat Major Depression

FemPulse Therapy First-in-Human Experience

Cognitive Enhancement in Depression (The COG-D Study)

Study of Low Field Magnetic Stimulation (LFMS) on Measures of Sleep

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

Transcutaneous (Tragus) Vagal Nerve Stimulation for Post-op Afib

Monitoring of Sleep and Behavior of Children 3-7 Years Old Receiving Parent-Child Interaction Therapy With the Help of Artificial Intelligence

Sensory Substitution and Brain Plasticity Following Vision Loss

Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer

Mitigating the Disinhibiting Effects of Alcohol With Transcranial Magnetic Stimulation

tDCS for Impulsivity and Compulsivity in Obesity

Controlled Trial of Gastric Electrical Stimulation in Children

Effects of tDCS and tUS on Pain Perception in OA of the Knee

Treatment for Migraines With an Implantable Device

High Intensity Focused Electromagnetic Field Device for Urinary Incontinence

Study of Low Level Laser Therapy for Body Contouring

Implant for Augmentation of Cerebral Blood Flow Trial, Effectiveness and Safety in a 24 Hour Window

Validation of New Devices Against Ambient Electromagnetic Radiation

Respiratory Muscle Function in Heart Failure