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These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:32 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1081–1104 of 1,165 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham-device Clear all

Conditions: Dysphagia
Interventions: swallowing therapy; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 90 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Chattanooga, Tennessee

Conditions: Osteo Arthritis Knee
Interventions: Active tDCS, Sham tDCS; Device
Lead sponsor: Florida State University; Other
Eligibility: 50 Years to 85 Years
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Prosthesis-Related Infections
Interventions: ABS deployed and active, ABS deployed and NOT active; Device
Lead sponsor: Nimbic Systems, LLC; Industry
Eligibility: 21 Years and older
Enrollment: 816 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Spinal Cord Injuries
Interventions: Acute Intermittent Hypoxia (AIH), Upper extremity training, Sham Acute intermittent hypoxia; Other · Behavioral
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 70 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Heart Failure With Reduced Ejection Fraction, Endothelial Dysfunction
Interventions: TVS, Sham TVS; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Cardiac Arrest
Interventions: Active Remote Ischemic Conditioning, Sham Remote Ischemic Conditioning; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Cardiovascular Diseases
Interventions: Portable air cleaner (PAC), Sham Portable air cleaner (PAC); Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 100 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Aphasia
Interventions: Soterix 1x1 tDCS; Device
Lead sponsor: Hunter College of City University of New York; Other
Eligibility: 18 Years to 100 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Obstructive Sleep Apnea
Interventions: Conservative Medical Therapy (CMT), Sham PAP (Sham), Active PAP with RT Support (Active-Beh), Active PAP with Behavioral Modification (Active+Beh); Behavioral · Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 45 Years to 75 Years
Enrollment: 169 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obstetric Anal Sphincter Injury, Vaginal Electrical Stimulation
Interventions: ApexM (Stimulation) Device, Sham Device; Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cancer Survivors, Obesity, Breast Cancer
Interventions: Inspiratory muscle training, Exercise training; Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder, Ehlers-Danlos Syndrome
Interventions: Transcutaneous Auricular Neurostimulation; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alzheimer Disease
Interventions: Active Neuro RX Gamma device, Sham Neuro RX Gamma device; Device
Lead sponsor: Vielight Inc.; Industry
Eligibility: 50 Years and older
Enrollment: 228 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Obesity
Interventions: g-Cath EZ™ Suture Anchor Delivery Catheter; Device
Lead sponsor: USGI Medical; Industry
Eligibility: 23 Years to 61 Years
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 11
States / cities: Scottsdale, Arizona • Miami, Florida • Dalton, Georgia + 8 more

Conditions: Type 2 Diabetes, Obstructive Sleep Apnea
Interventions: CPAP, Sham-CPAP, Diabetes Education; Device · Behavioral
Lead sponsor: Eileen R. Chasens; Other
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 4
States / cities: Detroit, Michigan • Pittsburgh, Pennsylvania • Morgantown, West Virginia

Conditions: Degenerative Cervical Myelopathy
Interventions: Transcutaneous spinal cord stimulation, Balance and Gait Training; Device · Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 50 Years to 90 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Malocclusion
Interventions: OrthoAccel Device, Sham Device; Device
Lead sponsor: OrthoAccel Technologies Inc.; Industry
Eligibility: 12 Years to 40 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Major Depressive Disorder, MDD
Interventions: tACS (alpha), tACS (gamma); Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Gambling Disorder, Gambling Addiction, Gambling Problem, Gambling
Interventions: Active Low-Intensity Focused Ultrasound (LIFU), Sham Low-Intensity Focused Ultrasound (LIFU); Device
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 60 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Restless Legs Syndrome
Interventions: Active CES Device Alpha-Stim®, Sham Device; Device
Lead sponsor: Tripler Army Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Honolulu, Hawaii

Conditions: Obesity, Body Weight, Fat Burn, Cellulite, Abdominal Fat, Adipose Tissue Atrophy
Interventions: Care as Usual Group, Sham Group; Device
Lead sponsor: IR Technology, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Hixson, Tennessee

Conditions: Feeding Delays, Neonates and Term Infants
Interventions: taVNS, NAC and taVNS, inactive taVNS, sterile water and inactive taVNS; Device · Combination Product
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 39 Weeks to 54 Weeks
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: IBS - Irritable Bowel Syndrome
Interventions: SynerGI, Sham VR; Device
Lead sponsor: Christopher Almario; Other
Eligibility: 10 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 2
States / cities: Los Angeles, California • Cleveland, Ohio

Conditions: Obstructive Sleep Apnea
Interventions: Mild Intermittent Hypoxia, Sham MIH; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 30 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Detroit, Michigan

Search by objective public record fields.

Adjunctive Neuromuscular Electrical Stimulation for the Rehabilitation of Swallowing

Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis

Air Barrier System for the Prevention of Prosthesis-related Infections

Daily Intermittent Hypoxia and Task-Specific Upper Limb Training in Persons With Chronic Incomplete SCI

Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function and Arterial Stiffness in HFrEF

Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot

Cleaner Air for Better Cardiac Biomarkers

tDCS and Aphasia Treatment

Sleep Apnea Intervention for Cardiovascular Disease Reduction

Vaginal Electrical Stimulation for Postpartum Neuromuscular Recovery

Inspiratory Muscle Training in Obese Breast Cancer Survivors

Hypermobile Ehlers-Danlos Syndrome - Transcutaneous Auricular Neuromodulation

Neuro RX Gamma - Pivotal Phase

ESSENTIAL Trial™ Sham Cross-over

Diabetes-Obstructive Sleep Apnea Treatment Trial

Stimulation-based Therapy to Improve Balance in DCM

Effect of Cyclic Loading (Vibration) on Orthodontic Tooth Movement

Transcranial Alternating Current Stimulation for Major Depressive Disorder

Low-Intensity Focused Ultrasound for Gambling Disorder

Cranial Electrotherapy for Military Beneficiaries With Restless Legs Syndrome

Comparing the Efficacy of a Dual-Frequency LLLT Device With a Sham Device as a Therapy for Adipose Tissue Loss

BabySTrong II taVNS Feeding Trial

RCT of VR Therapy for IBS

Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities