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ClinicalTrials.gov public records Last synced Nov 14, 2026, 6:36 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 89 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Smoking Relapse Prevention Clear all

Conditions: Smoking
Interventions: cognitive behavior therapy; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 304 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 2
States / cities: San Jose, California • Stanford, California

Conditions: Recurrence, Smoking Cessation, Substance-Related Disorders
Interventions: Varenicline, Placebo; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Smoking Cessation
Interventions: NRT + QuitBuddy, NRT + QuitBuddy-Recall, Treatment as Usual; Other
Lead sponsor: Meharry Medical College; Other
Eligibility: 18 Years and older
Enrollment: 94 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Smoking
Interventions: Standard Treatment Counseling, Culturally-Tailored Treatment; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Keshena, Wisconsin

Conditions: Substance Dependence
Interventions: GSK598809, Nicotine Replacement Transdermal Patch, Placebo; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 10
States / cities: DeLand, Florida • Pembroke Pines, Florida • Stockbridge, Georgia + 7 more

Conditions: Efficacy of Financial Incentives
Interventions: Voucher-based incentives; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 166 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Nicotine Dependence, Schizophrenia
Interventions: NRT, Bupropion SR 150mg bid, Relapse Prevention-Oriented Cognitive Behavioral Therapy; Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cigarette Smoking
Interventions: Smoking cessation guideline implementation; Behavioral
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older
Enrollment: 789 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Des Moines, Iowa • Iowa City, Iowa

Conditions: Neonatal Abstinence Syndrome
Interventions: Telemedicine, Group Care; Behavioral
Lead sponsor: Wendy F Hansen; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 269 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 11
States / cities: Ashland, Kentucky • Bowling Green, Kentucky • Corbin, Kentucky + 7 more

Conditions: Lung Cancer, Nonsmall Cell, COPD, Self-Management, Physical Inactivity, Stress, Quality of Life
Interventions: Breathe Easier; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: 21 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Postpartum Smoking Relapse
Interventions: Bupropion Extended Release Oral Tablet, Placebo oral tablet; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 161 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Nicotine Dependence
Interventions: Aerobic Exercise, Counseling, Nicotine patch; Behavioral · Drug
Lead sponsor: Jasper A. Smits; Other
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Hepatitis C, Smoking Cessation
Interventions: Cognitive Behavioral Counseling; Behavioral
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Nicotine Dependence
Interventions: Varenicline, Initial Individual counseling, Check-ins with medical staff, Extended Individual Counseling - Health Model, Extended Individual Counseling - Relapse Prevention Model; Drug · Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 216 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Smoking, Cigarette Smoking
Interventions: Helpers Stay Quit Training; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 99 Years
Enrollment: 940 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer, Head and Neck Cancer, Kidney Cancer, Leukemia, Liver Cancer, Lung Cancer, Pancreatic Cancer, Tobacco Use Disorder
Interventions: Smoking Prevention Usual Care, Counseling Intervention; Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 469 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2016
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Tobacco Use Disorder
Interventions: Progesterone, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 42 Years · Female only
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking Cessation
Interventions: Smoking Cessation; Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 3,830 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2016
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Human Immunodeficiency Virus, Smoking
Interventions: Bupropion, Varenicline, Cognitive Behavioral Therapy, Nicotine Replacement Therapy, Relapse Prevention Text Messaging; Drug · Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Hospitalized Smokers, Chronic Diseases, Tobacco Use Disorder
Interventions: Smoking relapse prevention; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Schizophrenia, Cigarette Smoking
Interventions: Nicotine replacement therapy, Bupropion, cognitive-behavioral smoking cessation counseling, Mobile Contingency Management, Stay Quit Coach, SMS text messaging; Drug · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Nicotine Dependence
Interventions: Sustained Care, Usual Care; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 422 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Smoking
Interventions: behavioral relapse prevention counseling, hypnosis for relapse prevention; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 80 Years
Enrollment: 139 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Smoking, Tobacco Use, Lung Cancer
Interventions: Nicotine patch and lozenges, Telephone counseling sessions, Access to a web-based video, Florida Tobacco Quitline; Drug · Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Tampa, Florida

Search by objective public record fields.

Behavioral Maintenance Treatment for Smoking Cessation

Relapse Prevention With Varenicline

Smoking Relapse Prevention Via Just-in-Time-Adaptive Interventions

Menominee Stop Tobacco Abuse Renew Tradition Study

Relapse Prevention Study in Newly Abstinent Smokers

Voucher Based Incentives to Treat Pregnant Smokers

Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia

The Effectiveness of Smoking Cessation Guidelines in the Emergency Department

The PATH Home Trial: A Comparative Effectiveness Study of Peripartum Opioid Use Disorder in Rural Kentucky

Breathe Easier II: A Dyad-based Multiple Behavior Intervention

Bupropion for the Prevention of Postpartum Smoking Relapse

Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.

HCV-Smoking Cessation Study

Maintaining Nonsmoking

Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks

Motivational Counseling in Preventing Smoking Relapse After Pregnancy in Pregnant Women Who Quit Smoking During Pregnancy

Progesterone for Smoking Relapse Prevention Following Delivery

Relapse-Prevention Booklets as an Adjunct to a Tobacco Telephone Helpline("Quitline")

Mobile Evidence-Based Smoking Cessation for Veterans Living With HIV (MESH)

Enhancing Tobacco Abstinence Following Hospitalization

Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia

Smoking Cessation Following Psychiatric Hospitalization

Hypnosis for Smoking Relapse Prevention

Project HEALS (Helping and Empowering pAtients for Living a Life Smoke-free