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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability

NCT01013077
View directory record Official record
Conditions
Dry Eye Syndrome
Interventions
Optive, Soothe, New Emulsion, Soothe, New Emulsion, Optive, New Emulsion, Optive, Soothe
Other
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 3, 2026, 1:09 AM EDT
Recruiting Not applicable Interventional

Effect of Music Therapy on Infants With Neonatal Abstinence Syndrome

NCT03533985
View directory record Official record
Conditions
NAS
Interventions
Song of Kin, Gato box, Ocean disc, Contingent singing, Tonal Vocal holding, Muted shaker
Behavioral · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
28 Weeks and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
6
States / cities
New Orleans, Louisiana • Hackensack, New Jersey • New Hyde Park, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep-Safe: A Strong African American Families Study

NCT03505203
View directory record Official record
Conditions
Weight Gain
Interventions
Sleep Soothe, Sleep Safe
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
17 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Phase 4 Interventional Results available

Efficacy of Ketorolac 0.4% in Prostaglandin Suppression

NCT00791323
View directory record Official record
Conditions
Inflammation
Interventions
Ketorolac 0.4%, Lubricating Eye Drop
Drug
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 22, 2011 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrated Behavioral Health Prevention in Pediatric Primary Care for Infants

NCT04825210
View directory record Official record
Conditions
Prevention
Interventions
Integrated Behavioral Health - Prevention, Bright Futures: Guidelines for Health Supervision of Infants, Children, and Adolescents, 4th Edition
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Phase 4 Interventional Results available

The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED

NCT02120079
View directory record Official record
Conditions
Dry Eye Disease
Interventions
Lotemax, Soothe Tired Eyes Lubricant Eye Drop (Artificial Tears), In Vivo Confocal Microscopy (IVCM)
Drug · Diagnostic Test
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Results available

Sleep Device Testing to Promote Sleep in Infants

NCT05078112
View directory record Official record
Conditions
Insomnia Chronic
Interventions
Sleep sensor technology
Device
Lead sponsor
Duke University
Other
Eligibility
2 Months to 12 Months
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Sep 3, 2026, 1:09 AM EDT
Active, not recruiting Phase 4 Interventional

Biofreeze® vs. a Placebo on Chronic Low Back Pain Walking Gait Characteristics and Pain

NCT03888820
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Biofreeze, Placebo
Drug
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional

Effect of Biofreeze® Versus Placebo on Acute Neck Pain, Disability, and Range of Motion

NCT03157349
View directory record Official record
Conditions
Acute Pain, Neck Pain
Interventions
Biofreeze, Placebo
Other
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Landover, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Phase 4 Interventional

Soothe Versus Refresh

NCT00284999
View directory record Official record
Conditions
Dry Eye Syndromes
Interventions
Soothe, Refresh Tears
Drug
Lead sponsor
Pharmaceutical Research Network
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2006
U.S. locations
3
States / cities
Atlanta, Georgia • Southfield, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2006 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Califormula Study: Calibrated Formula Feeding to Optimize Infant Growth

NCT05104073
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
1 Day to 1 Month
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Sep 3, 2026, 1:09 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Efficacy of Loteprednol Ointment Following Eyelid Surgery

NCT01749241
View directory record Official record
Conditions
Post-operative Healing Following Blepharoplasty and Ptosis Repair
Interventions
Loteprednol etabonate ophthalmic ointment, Vehicle Ophthalmic Ointment
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Sep 3, 2026, 1:09 AM EDT
Terminated No phase listed Observational

Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products

NCT03886753
View directory record Official record
Conditions
ALS, Autism Spectrum Disorder, Cancer, Spasticity, Muscle, Dyskinetic Syndrome, Epilepsy, Glaucoma, Huntington Disease, Inflammatory Bowel Disease (IBD), Multiple Sclerosis, Neuropathy, Opioid Use, Parkinson Disease, HIV/AIDS, Ptsd, Intractable Pain, Sickle Cell Disease, Terminal Illness
Interventions
Registry, PK microsampling of blood
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Phase 1 Interventional Results available

Biological Signatures, Probiotic Among Those With mTBI and PTSD

NCT02723344
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
Interventions
of Lactobacillus reuteri (L. reuteri; DSM 17938), Sunflower and medium chain triglyceride oils
Dietary Supplement · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Infant Behavioral Sleep Intervention: Comparative Efficacy

NCT03447665
View directory record Official record
Conditions
Insomnia
Interventions
Bedtime routine, Sleep schedule, Intervention (bedtime), Intervention (after night wakings)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
6 Months to 18 Months
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Oxymetazoline Drops for Acquired Blepharoptosis From Synkinesis

NCT05945615
View directory record Official record
Conditions
Blepharoptosis, Synkinesis, Hyperkinesis, Facial Paralysis
Interventions
Oxymetazoline 0.1% (Pf) Oph Soln Ud, Preservative free lubricating drops
Drug · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Objective Evaluation of Ocular Surface Lubricants in Two Environments

NCT01375582
View directory record Official record
Conditions
Dry Eye
Interventions
B & L Soothe Lubricant Eye Drops, Liposic EDO, OcuFresh Eye Wash
Drug
Lead sponsor
University of Rochester
Other
Eligibility
30 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Results available

Child Characteristics, Neuromarkers, and Intervention Components Impacting Treatment Outcome: CCT, TF-CBT, TAU

NCT02926677
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cue-Centered Treatment (CCT), Trauma-Focused CBT (TF-CBT), Treatment as Usual, NIRScout
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 18 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CARESS: An Investigation of Effects of CARESS

NCT03758027
View directory record Official record
Conditions
Craving, Self Efficacy, Affective; Reaction, Substance Abuse
Interventions
CARESS, Isometric Exercise
Behavioral
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 16, 2020 · Synced Sep 3, 2026, 1:09 AM EDT
Terminated Phase 4 Interventional

Biofreeze® vs. a Placebo on Knee Osteoarthritis Walking Gait Characteristics and Pain

NCT03888807
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Biofreeze, Placebo
Drug
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of VR on Pain and Patient Satisfaction in Adults Receiving GNRFA

NCT05468398
View directory record Official record
Conditions
Pain, Patient Satisfaction
Interventions
Soothe VR
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 3, 2026, 1:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Maternal Sleep and Mental Health

NCT06544941
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Sleep Disturbance, Infant Behavior, Maternal Behavior, Inflammation, Military Family
Interventions
Smart Bassinet, HALO
Device
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
342 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 3, 2026, 1:09 AM EDT
Completed Phase 2 Interventional Results available

Lotemax® Gel 0.5% and Restasis 0.05% in Participants With Mild or Moderate Keratoconjunctivitis Sicca (Dry Eye Disease)

NCT01817582
View directory record Official record
Conditions
Keratoconjunctivitis Sicca
Interventions
Lotemax, Restasis, Soothe® Lubricant Eye Drops
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
40 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Sep 3, 2026, 1:09 AM EDT