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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Spinal Cord Stimulation System Clear all
Recruiting Not applicable Interventional

Evaluation of an Advanced Lower Extremity Neuroprostheses

NCT00623389
View directory record Official record
Conditions
Spinal Cord Injuries, Stroke, Paralysis, Tetraplegia, Paraplegia
Interventions
IST (Implanted Stimulator-Telemeter)
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
21 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 24, 2026, 2:41 PM EDT
Not listed No phase listed Observational

LONG TERM EFFECTS OF SPINAL CORD STIMULATION

NCT06272955
View directory record Official record
Conditions
Parkinson Disease
Interventions
Spinal Cord Stimulator (SCS)
Device
Lead sponsor
Nora Vanegas
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Sep 24, 2026, 2:41 PM EDT
Completed Phase 4 Interventional Results available

Spinal Cord Stimulation for Low Back Pain

NCT00205868
View directory record Official record
Conditions
Chronic Pain
Interventions
Precision Spinal Cord Stimulation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
30
States / cities
Cullman, Alabama • Daphne, Alabama • Huntsville, Alabama + 27 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 24, 2026, 2:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways

NCT07401186
View directory record Official record
Conditions
Stroke, Able Bodied
Interventions
Bipolar Neural Stimulation Electrode
Device
Lead sponsor
Peter C. Gerszten, MD
Other
Eligibility
21 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 24, 2026, 2:41 PM EDT
Terminated Not applicable Interventional Results available

Effectiveness of Precision Spinal Cord Stimulation With Artisan Paddle Electrode

NCT00386724
View directory record Official record
Conditions
Back Pain, Chronic Pain, Pain in Leg, Unspecified
Interventions
Precision Spinal Cord Stimulation System, Artisan Surgical Lead
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Charleston, South Carolina • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 24, 2026, 2:41 PM EDT
Enrolling by invitation Not applicable Interventional

Medtronic Inceptiv™ Closed-Loop DTM Spinal Cord Stimulation for Painful Diabetic Peripheral Neuropathy

NCT07209514
View directory record Official record
Conditions
Diabetic Peripheral Neuropathic Pain (DPN)
Interventions
Implantable SCS with Closed Loop mechanism
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 24, 2026, 2:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing Non-Invasive Spinal Stimulation Devices

NCT07217314
View directory record Official record
Conditions
Healthy Participants
Interventions
Spinal Stimulation
Device
Lead sponsor
Gail Forrest
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 24, 2026, 2:41 PM EDT
Completed Not applicable Interventional Results available

ECAP-controlled, Closed-loop Stimulation to Treat Chronic Trunk and/or Limb Pain (ECAP)

NCT04319887
View directory record Official record
Conditions
Chronic Pain, Back Pain, Pain
Interventions
Evoke Spinal Cord Stimulation (SCS) System
Device
Lead sponsor
Saluda Medical Pty Ltd
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
22
States / cities
Little Rock, Arkansas • Carlsbad, California • Santa Rosa, California + 18 more
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Sep 24, 2026, 2:41 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Spinal Cord Stimulation With Precision® System Versus Reoperation for Failed Back Surgery Syndrome

NCT01036529
View directory record Official record
Conditions
Failed Back Surgery Syndrome, Pain, Back Pain
Interventions
Precision Spinal Cord Stimulator, Back Surgery
Device · Procedure
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
13
States / cities
La Jolla, California • Savannah, Georgia • Bloomington, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 15, 2020 · Synced Sep 24, 2026, 2:41 PM EDT
Completed Not applicable Interventional

Treatment of Pain and Autonomic Dysreflexia in Spinal Cord Injury With Deep Brain Stimulation

NCT02006433
View directory record Official record
Conditions
Pain, Autonomic Dysreflexia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Jonathan Jagid
Other
Eligibility
22 Years to 60 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 24, 2026, 2:41 PM EDT
Completed Not applicable Interventional Results available

Hand Function for Tetraplegia

NCT00890916
View directory record Official record
Conditions
Spinal Cord Injury, Tetraplegia
Interventions
FIRSTHAND System
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Sep 24, 2026, 2:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System

NCT02265848
View directory record Official record
Conditions
Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
Interventions
High frequency stimulation, Low frequency stimulation
Other
Lead sponsor
The Center for Clinical Research, Winston-Salem, NC
Other
Eligibility
18 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Sep 24, 2026, 2:41 PM EDT
Enrolling by invitation Not applicable Interventional

Efficacy and Feasibility of BurstDR SCS in Painful Diabetic Neuropathy

NCT07250828
View directory record Official record
Conditions
Painful Diabetic Neuropathy (PDN), Diabetic Neuropathy, Neuropathic Pain, Chronic Pain
Interventions
BurstDR Spinal Cord Stimulation
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 24, 2026, 2:41 PM EDT
Completed Not applicable Interventional Results available

PROLONG Prospective, Multi-center, Open-label, Post-market Study

NCT03908476
View directory record Official record
Conditions
Chronic Pain
Interventions
Burst-capable SCS system, DRG Stimulator
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
21
States / cities
Camarillo, California • Carlsbad, California • La Jolla, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 24, 2026, 2:41 PM EDT
Completed Not applicable Interventional Results available

Value of Multiple Modalities Using the Spectra WaveWriter Spinal Cord Stimulator System

NCT03251937
View directory record Official record
Conditions
Chronic Pain, Back Pain
Interventions
Spectra WaveWriter SCS System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
15
States / cities
Napa, California • Jupiter, Florida • Ocala, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Sep 24, 2026, 2:41 PM EDT
Recruiting Not applicable Interventional

Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury

NCT06213012
View directory record Official record
Conditions
Spinal Cord Injuries, Neuromodulation
Interventions
Transcutaneous Spinal cord Stimulation, Epidural Spinal Stimulation (ESS)
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
22 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 24, 2026, 2:41 PM EDT
Completed No phase listed Observational

Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS®) Real World Outcomes

NCT04725838
View directory record Official record
Conditions
Chronic Pain
Interventions
Medtronic Intellis™ and Vanta™
Device
Lead sponsor
Celéri Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
34
States / cities
Anchorage, Alaska • Oro Valley, Arizona • Sierra Vista, Arizona + 30 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Sep 24, 2026, 2:41 PM EDT
Terminated No phase listed Observational

Algovita Post-Market Clinical Study: Spinal Cord Stimulation to Treat Chronic Pain

NCT02373540
View directory record Official record
Conditions
Chronic Pain
Interventions
Algovita Spinal Cord Stimulation system
Device
Lead sponsor
Nuvectra
Industry
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
16
States / cities
Show Low, Arizona • Carlsbad, California • Los Gatos, California + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Sep 24, 2026, 2:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of Spinal Cord Stimulators on Restless Leg Syndrome

NCT07179406
View directory record Official record
Conditions
Restless Leg Syndrome (RLS), Spinal Cord Stimulation (SCS)
Interventions
H-Reflex, Somatosensory evoked potential (SSEP), Vibratory Electrophysiological Response Potential (ERP), Transcranial Magnetic Stimulation (TMS), Spinal Cord Stimulator (SCS) manipulation
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 24, 2026, 2:41 PM EDT
Terminated Phase 4 Interventional

Comparison of Intraspinal Nerve Root Stimulation With Dorsal Column Stimulation

NCT00370773
View directory record Official record
Conditions
Back Pain
Interventions
Precision Spinal Cord Stimulation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Daphne, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 4, 2008 · Synced Sep 24, 2026, 2:41 PM EDT
Completed Not applicable Interventional Results available

Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI

NCT05095454
View directory record Official record
Conditions
Paraplegia, Tetraplegia, Paralysis, Quadraplegia
Interventions
Percutaneous epidural electrical spinal stimulation, Transcutaneous electrical spinal stimulation
Device
Lead sponsor
Kristin Zhao, PhD
Other
Eligibility
22 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Sep 24, 2026, 2:41 PM EDT
Completed Not applicable Interventional Results available

DTM (TM) Spinal Cord Stimulation (SCS) Study

NCT04601454
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal Cord Stimulation System
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
13
States / cities
Walnut Creek, California • Carmel, Indiana • Somerset, Kentucky + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Sep 24, 2026, 2:41 PM EDT
Terminated Not applicable Interventional

Transcutaneous and Epidural Spinal Stimulation for Enabling Motor Function in Humans With Motor Complete Paraplegia

NCT03945331
View directory record Official record
Conditions
Paraplegia, Spinal, Paraplegia, Complete, Paraplegia; Traumatic
Interventions
Transcutaneous spinal cord stimulator, Epidural spinal cord stimulation system
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 24, 2026, 2:41 PM EDT
Recruiting No phase listed Observational

Post Market Evaluation of Real World Outcomes and Durability to Support Implantable Inceptiv™ Spinal Cord Stimulation Therapy

NCT07507422
View directory record Official record
Conditions
Chronic Pain, Intractable Pain
Interventions
Commercially available Inceptiv™ neurostimulation systems
Device
Lead sponsor
Medtronic
Industry
Eligibility
18 Years and older
Enrollment
970 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2034
U.S. locations
5
States / cities
Phoenix, Arizona • San Diego, California • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 24, 2026, 2:41 PM EDT