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Showing 1–24 of 241 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Spinal Fusion Clear all
Recruiting No phase listed Observational

Complex Adult Deformity Surgery (CADS)

NCT04194138
View directory record Official record
Conditions
Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
Interventions
Index or spine revision surgery for complex adult spinal deformity
Procedure
Lead sponsor
International Spine Study Group Foundation
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2032
U.S. locations
17
States / cities
La Jolla, California • Sacramento, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Not listed Not applicable Interventional

SPIRA™-A 3D and HCT/p DBM vs. Medtronic Divergent™-L/Perimeter™ and Recombinant BMP-2

NCT04566874
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Scoliosis
Interventions
ALIF
Device
Lead sponsor
Camber Spine Technologies
Industry
Eligibility
22 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Sep 5, 2026, 11:13 PM EDT
Not listed No phase listed Observational

NGS for Spine Surgery Patients

NCT05013203
View directory record Official record
Conditions
Spine Infection
Interventions
Tissue culture, Next Generation Sequencing
Diagnostic Test
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
450 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2021 · Synced Sep 5, 2026, 11:13 PM EDT
Terminated Not applicable Interventional Results available

Dynesys Spinal System Post Market 522 Study

NCT01528072
View directory record Official record
Conditions
Degenerative Spondylolisthesis, Pseudoarthrosis
Interventions
Dynesys Spinal System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years to 80 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
9
States / cities
Belleville, Illinois • Baltimore, Maryland • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Sep 5, 2026, 11:13 PM EDT
Enrolling by invitation Phase 4 Interventional

Comparing Outcomes in Patients Who Have Spinal Surgery Who Have No-Ice Cold and Compression Therapy Using the NICE1 Device Versus Standard of Care

NCT07542470
View directory record Official record
Conditions
Spinal Surgery, Spinal Fusion, Laminectomy
Interventions
ice-free cryopneumatic therapy device
Device
Lead sponsor
Sarasota Memorial Health Care System
Other
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Terminated Phase 4 Interventional Results available

IV Lidocaine in Pediatric AIS

NCT03893318
View directory record Official record
Conditions
Systemic Lidocaine Improves Pain Control After Surgery by Attenuating the Systemic Inflammatory Response to Surgery
Interventions
IV lidocaine, Placebos
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Not applicable Interventional

SIMDiscovery: The Benefits of Utilizing a Simulation Preparation Program for Spinal Fusion Surgery

NCT03835390
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent
Interventions
SIMDiscovery
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 18 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 6, 2020 · Synced Sep 5, 2026, 11:13 PM EDT
Completed No phase listed Observational

Posterior Lateral Fusion (PLF) With Dynesys

NCT00791180
View directory record Official record
Conditions
Spondylolisthesis
Interventions
Not listed
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 28, 2011 · Synced Sep 5, 2026, 11:13 PM EDT
Not listed Phase 4 Interventional

A Prospective Study of the InterFuse T(tm),

NCT02678130
View directory record Official record
Conditions
Low Back Pain
Interventions
InterFuse T, Standard of Care TLIF (Stryker AVS Unilif)
Device
Lead sponsor
Vertebral Technologies, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Sep 5, 2026, 11:13 PM EDT
Terminated No phase listed Observational

Prospective, Observational Registry of Renaissance-guided Spine Surgeries

NCT02212899
View directory record Official record
Conditions
Degenerative Spine Disease, Spinal Deformity
Interventions
Not listed
Lead sponsor
Mazor Robotics
Industry
Eligibility
6 Years to 90 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
4
States / cities
Jacksonville, Florida • Memphis, Tennessee • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Sep 5, 2026, 11:13 PM EDT
Recruiting Phase 2Phase 3 Interventional

IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study

NCT07217873
View directory record Official record
Conditions
Scoliosis Correction, Iron Deficiency, Transfusion Blood, Surgery Complications, Spinal Fusion, Scoliosis Idiopathic Adolescent, Scoliosis Neuromuscular
Interventions
Ferric carboxymaltose IV, Normal Saline (Placebo)
Drug
Lead sponsor
Columbia University
Other
Eligibility
10 Years to 19 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Not applicable Interventional Results available

Point of Care Testing in Pediatric Patients Undergoing Major Surgery

NCT01742936
View directory record Official record
Conditions
Spinal Fusion, Cardiopulmonary Bypass
Interventions
CoaguChek, Hospital Laboratory
Device · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
2 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 24, 2016 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Phase 3 Interventional

MAVERICK™ Total Disc Replacement- Pivotal Study

NCT00635843
View directory record Official record
Conditions
Spinal Diseases
Interventions
MAVERICK™ Disc, LT-CAGE® Lumbar Tapered Fusion Device and INFUSE® Bone Graft
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years to 70 Years
Enrollment
577 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
32
States / cities
Huntsville, Alabama • Daly City, California • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2013 · Synced Sep 5, 2026, 11:13 PM EDT
Active, not recruiting Phase 2 Interventional

Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery

NCT03841058
View directory record Official record
Conditions
Spinal Fusion
Interventions
Abaloparatide, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Effect of RECK in Posterior Spinal Fusion

NCT06447194
View directory record Official record
Conditions
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
Interventions
Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo
Drug · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Not listed No phase listed Observational

A Retrospective Study to Examine the Effect of CMF Stimulation on Primary ACDF Patients

NCT05101057
View directory record Official record
Conditions
Degeneration of Cervical Intervertebral Disc
Interventions
SpinalogicTM Bone Graft Stimulator
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
18 Years to 75 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
San Diego, California • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Sep 5, 2026, 11:13 PM EDT
Terminated Phase 2 Interventional Results available

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

NCT02388165
View directory record Official record
Conditions
Staphylococcal Vaccine
Interventions
Staphylococcus aureus 4-Antigen (SA4Ag) Vaccine, Placebo
Biological · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 85 Years
Enrollment
3,450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
234
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 89 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Sep 5, 2026, 11:13 PM EDT
Completed No phase listed Observational

Fibergraft Interbody Fusion Retrospective

NCT03898232
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Degeneration, Spinal Stenosis
Interventions
Computed Tomography (CT) Scan of the Lumbar Spine
Radiation
Lead sponsor
Bone and Joint Clinic of Baton Rouge
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Sep 5, 2026, 11:13 PM EDT
Completed No phase listed Observational

Comprehensive Spinal Alignment Planning Study

NCT02606695
View directory record Official record
Conditions
Spine Surgery
Interventions
NuvaMap O.R., NuvaMap
Device
Lead sponsor
NuVasive
Industry
Eligibility
18 Years and older
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
15
States / cities
La Jolla, California • Orange, California • San Diego, California + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MMG vs. EMG for Cortical Breach Detection

NCT05352048
View directory record Official record
Conditions
Low Back Disorder
Interventions
Triggered Electromyography, Mechanomyography
Device
Lead sponsor
Francis Farhadi
Other
Eligibility
18 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

NCT05504499
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Interspinous Fusion
Device
Lead sponsor
Pacific Research Institute
Network
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
10
States / cities
Santa Rosa, California • Jupiter, Florida • Slidell, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2022 · Synced Sep 5, 2026, 11:13 PM EDT
Not listed Not applicable Interventional

SynerFuse Spinal Fusion and Neuromodulation Proof of Concept Study

NCT04054401
View directory record Official record
Conditions
Spinal Fusion, Radiculopathy Lumbar, Chronic Pain
Interventions
DRG Neurostimulation with Spinal Fusion
Device
Lead sponsor
SynerFuse, Inc
Other
Eligibility
21 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Mishawaka, Indiana • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 23, 2023 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease

NCT03733626
View directory record Official record
Conditions
Lumbar Spondylolisthesis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Lumbar Radiculopathy, Lumbar Spinal Stenosis, Lumbar Disc Disease
Interventions
ViviGen® Cellular Bone Matrix with DePuy Synthes Spinal Pedicle screw system, Local Bone Autologous Bone Graft with DePuy Synthes Spinal pedicle screw system
Combination Product
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Assessing Superion Clinical Endpoints vs. Decompression

NCT03048955
View directory record Official record
Conditions
Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Interventions
Superion® IDS, Direct decompression Surgery
Device · Procedure
Lead sponsor
VertiFlex, Incorporated
Industry
Eligibility
45 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
5
States / cities
Birmingham, Alabama • Carlsbad, California • Celebration, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Sep 5, 2026, 11:13 PM EDT