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ClinicalTrials.gov public records Last synced Oct 17, 2026, 7:26 AM EDT

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Showing 1–24 of 4,380 matching trials from the live ClinicalTrials.gov search.
Conditions
Esophageal Neoplasm, Esophageal Polyp, Endoscopic Submucosal Dissection, Bipolar Electocautery
Interventions
Endoscopic Submucosal Dissection, Bipolar electrocautery knife
Procedure · Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Conditions
Liver Biopsy
Interventions
biopsy
Diagnostic Test
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Orlando, Florida
Active, not recruiting Not applicable Interventional Results available

Screening for Colorectal Cancer in Older Patients (PLCO Screening Trial)

NCT01696981
Conditions
Colon Carcinoma, Rectal Carcinoma
Interventions
Screening Questionnaire Administration, Sigmoidoscopy
Other · Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
55 Years to 74 Years
Enrollment
154,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

NCT04232566
Conditions
Obesity, Morbid, NASH - Nonalcoholic Steatohepatitis, Chronic Inflammation
Interventions
Bariatric surgery
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Scottsdale, Arizona
Conditions
Psychological Distress, Intra-abdominal Cancer
Interventions
Mindfulness Intervention, Non-mindfulness Intervention
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Not listed Phase 4 Interventional Accepts healthy volunteers

Does Intrathecal Morphine Affect Outcomes in Spine Deformity Surgery

NCT05092828
Conditions
Low Back Pain
Interventions
Intrathecal Morphine Injection, Pain Relieving
Drug
Lead sponsor
Sonoran Spine Research and Education Foundation
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Tempe, Arizona
Conditions
Bladder Cancer
Interventions
Prostate capsule-sparing radical cystectomy, Nerve sparing radical cystectomy
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Male only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Completed Phase 4 Interventional Results available

Pre vs Post Block in Total Knee Arthroplasty (TKA)

NCT05974501
Conditions
Knee Osteoarthritis, Arthroplasty Complications, Postoperative Pain
Interventions
Dexamethasone, Acetaminophen, Lyrica, Celebrex, Meloxicam, Oxycodone, Ropivacaine
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Miami, Florida
Conditions
Ureter Injury
Interventions
filricianine
Drug
Lead sponsor
Intuitive Surgical
Industry
Eligibility
16 Years to 75 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
9
States / cities
Newport Beach, California • New Haven, Connecticut • Orlando, Florida + 6 more
Conditions
Malignant Female Reproductive System Neoplasm
Interventions
Hydromorphone, Laparotomy, Liposomal Bupivacaine, Questionnaire Administration
Drug · Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Tennis Elbow, Lateral Epicondylitis
Interventions
Smith & Nephew Bioinductive Implant, Lateral Epicondylectomy, Ultrasound Imaging
Biological · Procedure · Radiation
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Invasive Breast Carcinoma, Triple-Negative Breast Carcinoma
Interventions
Bevacizumab, Everolimus, Laboratory Biomarker Analysis, Pegylated Liposomal Doxorubicin Hydrochloride
Biological · Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Houston, Texas
Completed No phase listed Observational Results available

Use of Hextend in Trauma

NCT00983281
Conditions
Trauma
Interventions
Hextend
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
1,714 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Miami, Florida
Conditions
Post Operative Surgical Site Infection
Interventions
Standard of care, Vancomycin and Tobramycin
Drug
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 64 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
31
States / cities
Redwood City, California • San Francisco, California • Aurora, Colorado + 25 more
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Fatigue in Long-Haul Operations

NCT07761611
Conditions
Alertness, Fatigue, Mood, and Performance, Calorie Restriction and Light Intervention
Interventions
Caloric restriction, Light exposure
Behavioral · Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Mountain View, California
Conditions
Sarcoma
Interventions
Non-Metastatic and Resectable, Metastatic and Un-resectable, No evidence of disease, under surveillance, ALT or WDLS
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Charlotte, North Carolina • Winston-Salem, North Carolina
Conditions
Chronic Obstructive Pulmonary Disease, Lung Cancer
Interventions
Pulmonary Rehab
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Burlington, Vermont
Not listed Phase 2 Interventional Accepts healthy volunteers

Topical Timolol: a Comparison of Surgical Outcomes

NCT05114239
Conditions
Wound Heal
Interventions
Timolol 0.25% Ophthalmic Solution, Standard Wound Care
Drug · Other
Lead sponsor
Keith G. LeBlanc, Jr, MD
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Metairie, Louisiana
Terminated Phase 3 Interventional Results available

Alvimopan as Rescue in Post op Ileus

NCT02742181
Conditions
Colorectal Surgery, Ileus
Interventions
Alvimopan, Control Group
Drug · Other
Lead sponsor
Sharon Stein
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Allergic Contact Dermatitis (ACD)
Interventions
Dermabond PRINEO, Silk fibroin
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Conditions
ACL Reconstruction, Meniscus Tears, Anterior Cruciate Ligament Rupture
Interventions
Semiconducting fabric sleeves, Non-semiconducting fabric sleeves
Device
Lead sponsor
Illinois Center for Orthopaedic Research and Education
Other
Eligibility
16 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Westmont, Illinois
Conditions
Nerve Injury, Peripheral Nerve Injuries, Peripheral Nerve Injury Upper Limb, Nerve Palsy
Interventions
Checkpoint BEST System
Device
Lead sponsor
Checkpoint Surgical Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Laparoscopic Cholecystectomy, Robotic-assisted Cholecystectomy
Interventions
Laparoscopic cholecystectomy, Robotic-assisted cholecystectomy
Procedure
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years to 80 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
4
States / cities
Miami, Florida • New Lenox, Illinois • Albuquerque, New Mexico + 1 more
Conditions
Appendicitis
Interventions
Cold Therapy, Standard of Care
Device · Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
7 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts