Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:51 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 106 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Staple Clear all

Conditions: Cesarean Section
Interventions: Insorb absorbable skin staple; Device
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 12 Years to 55 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Wound Infection
Interventions: Purse string closure, Primary closure; Procedure
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Wound Infection
Interventions: There is no intervention for this study; Other
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 14 Years to 50 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Rectal Cancer, Ulcerative Colitis, Familial Adenomatous Polyposis, Diverticulitis
Interventions: GORE SEAMGUARD® Bioabsorbable Staple Line Reinforcement, Staple line without reinforcement; Device · Procedure
Lead sponsor: W.L.Gore & Associates; Industry
Eligibility: 18 Years and older
Enrollment: 258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 16
States / cities: Mobile, Alabama • Los Angeles, California • Weston, Florida + 12 more

Conditions: Surgical Wound
Interventions: Surgical staples, Subcuticular sutures; Procedure
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Ventral Hernia
Interventions: Strattice Arm, Bio-A Arm; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Gastric Procedures, Lung Resection Procedures
Interventions: Staple Line Reinforcement; Device
Lead sponsor: Ethicon Endo-Surgery; Industry
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 8
States / cities: Indianapolis, Indiana • Baton Rouge, Louisiana • Detroit, Michigan + 5 more

Conditions: Wound Complications, Wound Infection, Wound Separation
Interventions: Prospective wound complication protocol; Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 89 Years · Female only
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Burns Degree Third, Burn (Disorder), Burn Degree Second, Thermal Burn, Wound Heal
Interventions: Skin Xenotransplant, Autograft(ing); Drug · Procedure
Lead sponsor: XenoTherapeutics, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 4
States / cities: Phoenix, Arizona • Augusta, Georgia • Portland, Maine + 1 more

Conditions: Colonic Diseases, Rectal Diseases
Interventions: Bipolar electrosurgical generator and instruments, Disposable stapling instruments; Procedure
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Morbid Obesity
Interventions: Laparscopic Sleeve Gastrectomy, Weight Watchers Program; Procedure · Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 65 Years · Female only
Healthy volunteers: Accepts healthy volunteers
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Wound Heal
Interventions: DERMABOND, Staples; Device
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Adolescent Idiopathic Scoliosis
Interventions: The Spinal Tethering System; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 10 Years to 23 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Bariatric - Sleeve Gastrectomy Staple Line Reinforcement, Gynecology - Vaginal Cuff Closure
Interventions: Robotic Suturing of gastric sleeve oversew and vaginal cuff closure; Device
Lead sponsor: Ethicon, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 161 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 4
States / cities: Miami, Florida • Albany, New York • New York, New York

Conditions: Deep Full-thickness Burn Injury (Disorder)
Interventions: realSKIN (skin xenotransplant), Human Cadaver Allograft; Biological
Lead sponsor: XenoTherapeutics, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 2
States / cities: Augusta, Georgia • Boston, Massachusetts

Conditions: Rectal Cancer, Anastomotic Leak
Interventions: LifeSeal™ Kit; Device
Lead sponsor: LifeBond Ltd.; Industry
Eligibility: 21 Years and older
Enrollment: 736 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 23
States / cities: Los Angeles, California • Stanford, California • Florida City, Florida + 17 more

Conditions: Deep Partial Thickness Burn, Full Thickness Burns
Interventions: Mepitel One; Device
Lead sponsor: Molnlycke Health Care AB; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 4
States / cities: Tampa, Florida • Augusta, Georgia • Kansas City, Kansas + 1 more

Conditions: Sleep Apnea, Hypertension, Hyperlipidemia, Coronary Artery Disease, Gastroesophageal Reflux Disease, Osteoarthritis, Diabetes
Interventions: Tri Staple Technology stapler; Device
Lead sponsor: Medtronic - MITG; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Ileus
Interventions: MOA-728, Placebo; Drug
Lead sponsor: Bausch Health Americas, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 374 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 75
States / cities: Benton, Arkansas • Colton, California • Laguna Hills, California + 62 more

Conditions: Wound
Interventions: Surgical staples, Absorbable Surgical Suture; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 16 Years and older · Female only
Enrollment: 398 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: High Risk Abdominal Wounds
Interventions: Negative Pressure treatment; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 95 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Arthroplasty, Replacement, Knee
Interventions: Zip Surgical Skin Closure, Steel Staples; Device
Lead sponsor: ZipLine Medical Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: AAA Graft Implant for Primary Aneurysm Treatment, AAA Graft Repair to Extend Life of Implant
Interventions: EndoRefix; Device
Lead sponsor: Lombard Medical; Industry
Eligibility: 21 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 7
States / cities: Birmingham, Alabama • Phoenix, Arizona • Atlanta, Georgia + 4 more

Conditions: Post-Operative Ileus (POI)
Interventions: Methylnaltrexone, Placebo; Drug
Lead sponsor: Bausch Health Americas, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 524 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Tarrytown, New York

Search by objective public record fields.

A Study Comparing Two Different Techniques for Closing the Skin After a Cesarean Delivery

A Randomized Trial of Ostomy Closure Techniques

Use of Insorb Absorbable Vicryl Staples in Skin Closure for Cesarean Section

Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses

Outcomes Comparing Different Methods of Skin Closure in Patients Undergoing Head and Neck Surgery.

The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients

Study of ECHELON ENDOPATH(TM) Staple Line Reinforcement

A Study to Evaluate a Quality Improvement Intervention to Reduce Wound Separation Rates in Obese Gynecologic Oncology Service Patients Undergoing Abdominal Surgery

Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting

Random Comparison of LigaSure and Disposable Staples for Laparoscopic Surgery

Laparoscopic Sleeve Gastrectomy Plus Weight Watchers vs. Weight Watchers Alone in Underserved Minority Women

Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty

Safety and Efficacy Study of Spinal Tethering

Post-Market Clinical Follow-Up of STRATAFIX™ Spiral PDS™ PLUS

Evaluation of Safety and Efficacy of realSKIN® (Skin Xenotransplant) for Complete Closure of Severe Burn Wounds

Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing

Open, Prosp, Rand. Invest. Evaluating Pain With Mepitel One vs.Bridal Veil and Staples on Split Thickness Skin Grafts

Tri Staple Technology Stapler Used in Gastric Bypass

A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair

Staples Versus Suture for Cesarean Wound Closure

Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions

ZIPS Study - Zip Incision Approximation vs. STAPLE

Evaluation of EndoRefix Endovascular Delivery System and Staple

Study of Intravenous (IV) Methylnaltrexone Bromide (MNTX) in the Treatment of Post-Operative Ileus (POI)