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ClinicalTrials.gov public records Last synced Oct 31, 2026, 10:12 AM EDT

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Showing 217–240 of 390 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Step-Up Intervention Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Improving Efficacy of Voice Therapy Concepts Via Telepractice and Mobile App Technology

NCT05220982
View directory record Official record
Conditions
Voice Disorders
Interventions
Conversation Training Therapy, Global Voice Prevention and Therapy Model, Modified Conversation Training Therapy, Modified Global Voice Prevention and Therapy Model
Behavioral
Lead sponsor
West Chester University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
West Chester, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional Results available

Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)

NCT02873754
View directory record Official record
Conditions
Smoking
Interventions
Cognitive Behavioral Counseling, Mobile Contingency Management, Bupropion, Transdermal nicotine patch, Nicotine polacrilex, Nicotine lozenge
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2018 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

ASUKI Step Pedometer Worksite Intervention

NCT01537939
View directory record Official record
Conditions
Physical Activity
Interventions
ASUKI Step Worksite Pedometer Intervention
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
2,018 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 23, 2012 · Synced Oct 31, 2026, 10:12 AM EDT
Recruiting Phase 3 Interventional

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

NCT03567889
View directory record Official record
Conditions
Melanoma Stage IIIB, Melanoma Stage IIIC, Melanoma Stage IIID
Interventions
Daromun, Surgery, Adjuvant therapy
Drug · Procedure
Lead sponsor
Philogen S.p.A.
Industry
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2031
U.S. locations
19
States / cities
Phoenix, Arizona • La Jolla, California • Orange, California + 16 more
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional

Scale Down for Endometrial Cancer

NCT03169023
View directory record Official record
Conditions
Endometrial Cancer, Cancer of the Endometrium
Interventions
ScaleDown, Enhanced Usual Care Packets, 12-Item Short Form Health Survey, International Physical Activity Questionnaire short form, Multidimensional Body Self Relations Questionnaire - Appearance Subscales, Cancer-Related Body Image Scale, Patient Health Questionnaire 9-Item Version, iOTA
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 28, 2019 · Synced Oct 31, 2026, 10:12 AM EDT
Recruiting Not applicable Interventional

Developing a Digital Aid to Improve ICD Decisions

NCT07084142
View directory record Official record
Conditions
Heart Failure and Reduced Ejection Fraction
Interventions
Online, patient-facing decision-making aid (app) with personalized risk information., Implantable Cardioverter Defibrillator (ICD), Online, patient-facing decision-making app without personalized risk information.
Other · Device
Lead sponsor
Stanford University
Other
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
San Francisco, California • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 31, 2026, 10:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Assessing the Impact of myHealth Rewards Enrollment Emails

NCT03965754
View directory record Official record
Conditions
Health Promotion, Wellness Programs
Interventions
Social norms, Loss framing, Email reminder
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
5,697 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Oct 31, 2026, 10:12 AM EDT
Recruiting No phase listed Observational

Observational PIC Destination Cohort

NCT05985642
View directory record Official record
Conditions
HIV-1-infection
Interventions
Not listed
Lead sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Network
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
4
States / cities
San Francisco, California • St Louis, Missouri • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adaptive Intervention to Maximize Colorectal Screening in Safety Net Populations

NCT03100461
View directory record Official record
Conditions
Colorectal Cancer
Interventions
I2, Health Education
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
50 Years to 75 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Acupuncture Treatment for Dysphagia

NCT00797732
View directory record Official record
Conditions
Carcinomas, Squamous Cell, Dysphagia
Interventions
Acupuncture
Device
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional

Stepping Up: A Trial of Activity Monitoring Devices in Patients Undergoing Autologous Stem Cell Transplant

NCT04985409
View directory record Official record
Conditions
Multiple Myeloma, Lymphoma, Transplant-Related Disorder
Interventions
Feedback
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2022 · Synced Oct 31, 2026, 10:12 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Improving Colorectal Cancer Screening Uptake Through Education and Stool-Based Testing Outreach

NCT07781774
View directory record Official record
Conditions
Colorectal Cancer (CRC) Screening, CRC Screening, Rectal Cancer, Colon Cancer, Colorectal Cancer
Interventions
Colorectal Cancer Education Materials, Cologuard test kit, Fecal immunochemical test kit, Usual Care
Behavioral · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
45 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 31, 2026, 10:12 AM EDT
Active, not recruiting Not applicable Interventional

Lifestyle Physical Activity Intervention for Persons Newly Diagnosed With Multiple Sclerosis

NCT06355804
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Physical activity condition, Waitlist condition
Behavioral
Lead sponsor
University of Illinois Chicago
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 31, 2026, 10:12 AM EDT
Recruiting Not applicable Interventional

Opioid Tapering After Hospital Discharge: Testing an Intervention to Improve Post-operative Opioid Prescribing

NCT07510373
View directory record Official record
Conditions
Opioid Tapering
Interventions
Treatment as Usual (TAU), Telephonic Support (TS) Providers, DOTS Intervention
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 31, 2026, 10:12 AM EDT
Recruiting Not applicable Interventional

Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

NCT04142177
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Pain EASE, Tailored exercise, Continued Care and Active Monitoring, Cognitive Behavioral Therapy (CBT), Spinal Manipulation Therapy (SMT), Yoga
Other · Procedure · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
2,529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
19
States / cities
Phoenix, Arizona • Loma Linda, California • Long Beach, California + 16 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional Results available

Trial of Self-managed Approaches for Patellofemoral Pain Syndrome in Active Duty

NCT02597673
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Home Exercise Program (HEP), NMES, TENS
Other · Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 45 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 1, 2020 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional Results available

Implementation and Evaluation of a Diabetes Prevention Clinical Pathway in Primary Care

NCT05265312
View directory record Official record
Conditions
PreDiabetes, Prediabetic State
Interventions
START diabetes prevention clinical pathway
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
1,910 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 31, 2026, 10:12 AM EDT
Recruiting Not applicable Interventional

Prehabilitation Physical Therapy and Relaxation Intervention Program to Promote Resiliency and Operative Success Among Adults Receiving Lung Cancer Surgery, ROAR-LCS Trial

NCT07584239
View directory record Official record
Conditions
Resectable Lung Non-Small Cell Carcinoma
Interventions
Biospecimen Collection, Exercise Intervention, Internet-Based Intervention, Physical Therapy, Relaxation Technique, Survey Administration, Text Message-Based Navigation Intervention
Procedure · Other · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 31, 2026, 10:12 AM EDT
Withdrawn Phase 4 Interventional

Anxiety and Depression in Epilepsy: A Pilot Treatment Study

NCT03522987
View directory record Official record
Conditions
Anxiety, Depression, Epilepsy
Interventions
Escitalopram 10mg
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Oct 31, 2026, 10:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Two School-Based Sleep Health Interventions To Promote Sleep Quality in Youth

NCT07213908
View directory record Official record
Conditions
Sleep
Interventions
TS-C-STEP, Sleep Health Education (SHE)
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
12 Years to 18 Years
Enrollment
1,320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
2
States / cities
Los Angeles, California • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Phase 3 Interventional

Treating Tobacco Dependence in Adolescents With Co-occurring Psychiatric Disorders

NCT00618943
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Use Disorder
Interventions
Tobacco Use Cessation
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
3
States / cities
San Bruno, California • San Francisco, California • San Mateo, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2011 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Physical Activity Program to Disrupt Sedentary Time in Older Latinos

NCT04507464
View directory record Official record
Conditions
Sedentary Behavior, Cognitive Impairment
Interventions
Ecological Momentary Intervention
Behavioral
Lead sponsor
University of Illinois Chicago
Other
Eligibility
55 Years to 89 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safe Spaces 4 Sexual Health

NCT07133555
View directory record Official record
Conditions
HIV Counseling and Testing, HIV Risk Behavior, HIV Prevention
Interventions
Healthcare counseling service
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 49 Years · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 31, 2026, 10:12 AM EDT
Completed Not applicable Interventional Results available

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

NCT03423238
View directory record Official record
Conditions
Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions
Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling
Other · Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Oct 31, 2026, 10:12 AM EDT