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ClinicalTrials.gov public records Last synced Nov 9, 2026, 7:38 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 145 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Stress Challenge Clear all

Conditions: Pregnancy Related, Stress, Psychological, Glucose Intolerance During Pregnancy, Emotional Stress, Postprandial Hyperglycemia, Insulin Sensitivity/Resistance
Interventions: Psychosocial stress, Control non-stress; Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Irvine, California • Orange, California

Conditions: Cannabis Use
Interventions: Trier Social Stress Task (TSST); Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 50 Years to 80 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Stress Disorders, Post-Traumatic
Interventions: Adjunctive writing to amplify response and engagement (AWARE), Cognitive processing therapy (CPT), Prolonged exposure (PE); Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cancer
Interventions: Wakeful Spanish; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 39 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Autism Spectrum Disorder
Interventions: Surviving and Thriving in the Real World, Program for the Education and Enrichment of Relational Skills; Behavioral
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 15 Years to 22 Years
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Coronary Endothelial Dysfunction, Apical Ballooning Syndrome, Myocardial Infarction
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 190 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2011
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pregnancy, High Risk, Child Development, Post Partum Depression
Interventions: Nurse Family Partnership; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 16 Years to 46 Years · Female only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Dementia, Caregiver Burnout
Interventions: Savvy Caregiver Program via Remote Learning, Focus group; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Stress, Psychological
Interventions: MBRT ClassRoom and Phone Application, Phone application only, Questionnaires; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Anxiety
Interventions: Brief Cognitive Behavioral Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: New Orleans, Louisiana • Houston, Texas • San Antonio, Texas

Conditions: Pregnancy Related, Stress, Psychological, Glucose Intolerance During Pregnancy
Interventions: Trier Social Stress Test, Placebo Non-stress task; Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Orange, California

Conditions: Stress, Psychological
Interventions: Stress and emotion management; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 40 Years and older · Female only
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Preterm Birth, Inflammation, Stress, Mental Health Issue
Interventions: Cognitive Challenge; Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Dietary Modification
Interventions: Tart cherry Juice, High-fat meal, Exercise; Dietary Supplement · Other
Lead sponsor: University of Georgia; Other
Eligibility: 18 Years to 30 Years · Male only
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Athens, Georgia

Conditions: PTSD
Interventions: Cognitive Processing Therapy, STAIR Narrative Therapy; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Palo Alto, California • San Francisco, California

Conditions: Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis, Depressive Disorder, Anxiety Disorder, Stress Disorders, Post-Traumatic
Interventions: Acceptance and Commitment Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2028 – 2032
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Covid19, Risk Reduction, Stress, Sleep
Interventions: Hiking challenge, Activity list; Behavioral · Other
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Organ Transplant
Interventions: Mindfulness-Based Stress Reduction (MSBR), Health Education (HE), Delayed Intervention; Behavioral
Lead sponsor: National Institute of Nursing Research (NINR); NIH
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Potential Treatment for Alcohol Dependence-Alcohol Interaction
Interventions: PT150, Beverage; Drug · Other
Lead sponsor: Pop Test Oncology LLC; Industry
Eligibility: 21 Years to 64 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Stress, Mindfulness, Early Life Adversity
Interventions: Mindfulness-Based Stress Reduction (MBSR); Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 29 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hypertension
Interventions: MIND-BP, BOOST; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Trauma, Posttraumatic Stress Disorder
Interventions: Trier Social Stress Test (TSST), No stress condition; Behavioral · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 30 Years
Enrollment: 197 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Opioid-use Disorder
Interventions: Kids Kicking Cancer program; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Mental Health, Work Related Stress
Interventions: Coaching and Advancement for Peer Providers (CAPP); Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Years and older
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

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Emotion-Diet Interactions in Pregnancy

Stress-Reactivity and Cannabis Use in Cannabis-Using Older Adults

Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication

Meditation, Education, Navigation, & Training Using eHealth: Cancer Adaptation Through Learning Mindful Awareness

Daily Living Skills Intervention for Adolescents With Autism Spectrum Disorder

The Relationship Between the Response to Mental Stress and Vascular Endothelial Function

Nurse Family Partnership for Women With Previous Live Births

Equality in Caregiving: Facilitating Caregiver Mastery Among LGBT Caregivers of PLWD

Mindfulness Based Resilience Training

A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care

Maternal Emotions and Diet in Pregnancy

OUR Stress/ Emotion Management for Black/African American Women With Hypertension

Stress Phenotypes and Preterm Birth

Antioxidant Responses to Exercise and Cherry Consumption

A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations

ACT for Veterans With IBD and Mental Health Challenges

The Get Outside Study

Wellness Interventions After Transplant Study

Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)

Remote Mindfulness Training Following Early Life Adversity 2

Jackson Heart Study Women's Hypertension Study

Stress-induced Drinking in Emerging Adults: the Role of Trauma History

The Heroes Circle Opioid Project

Testing the Effectiveness of Mainstream Management Tools to Increase Organizational Commitment and Job Satisfaction and Decrease Turnover Among Peer Providers