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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sub symptom aerobic exercise Clear all
Completed Not applicable Interventional

Restoring Energy With Sub-symptom Threshold Optimized Rehabilitation Exercise for Long COVID

NCT06172803
View directory record Official record
Conditions
Long Covid19, Exercise Intolerance, Riboflavin-Responsive
Interventions
Restoring Energy with Sub-symptom Threshold Aerobic Rehabilitation Exercise, Light Stretching/Breathing Exercises
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Results available

Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion

NCT02710123
View directory record Official record
Conditions
Brain Injury, Concussion
Interventions
Sub-Threshold exercise prescription, Structured stretching prescription
Other
Lead sponsor
University at Buffalo
Other
Eligibility
10 Years to 18 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Results available

Exercise and Pharmacotherapy for Anxiety in Cardiac Patients

NCT02516332
View directory record Official record
Conditions
Anxiety, Cardiovascular Disease
Interventions
Lexapro, Placebo, Supervised Aerobic Exercise
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
40 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Sep 15, 2026, 10:26 AM EDT
Recruiting Not applicable Interventional

PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF

NCT07324772
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal), Persistent Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFPEF)
Interventions
progressive resistance training, combined aerobic + resistance training
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Concussion Therapy Intervention Training in Healthy and Concussed Participants

NCT02872480
View directory record Official record
Conditions
Cerebral Concussion
Interventions
ACTIVE Training
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 30 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2017 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Early Exercise to Improve Psychosocial Function After Pediatric Mild Traumatic Brain Injury

NCT04199247
View directory record Official record
Conditions
Brain Concussion, Pediatric, Mild Traumatic Brain Injury, Psychological
Interventions
Sub symptom aerobic exercise
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 18 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Aerobic Training for Management of Post-Concussion Syndrome in Adolescents

NCT02035579
View directory record Official record
Conditions
Concussion, Post-concussion Syndrome, Sports Injury
Interventions
Aerobic Training Intervention, Stretching Intervention
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 10, 2016 · Synced Sep 15, 2026, 10:26 AM EDT
Withdrawn Not applicable Interventional

Reconditioning Exercise for COVID-19 Patients Experiencing Residual sYmptoms

NCT04958161
View directory record Official record
Conditions
Covid19
Interventions
Exercise Therapy
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Sep 15, 2026, 10:26 AM EDT
Terminated Not applicable Interventional

A Comparison Between Cardiovascular Exercise Modes Following Sport Related Concussion

NCT04586179
View directory record Official record
Conditions
Concussion, Mild, Sport Injury
Interventions
Aerobic (treadmill) Exercise, Dynamic (Agility) Exercise
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 35 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 15, 2026, 10:26 AM EDT
Recruiting Not applicable Interventional

Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women With Hormone Receptor Positive Advanced Breast Cancer

NCT06123988
View directory record Official record
Conditions
HER2-positive Breast Cancer, Advanced Breast Cancer
Interventions
Prolonged Overnight Fasting, Moderate-Intensity Exercise, General Health Education Sessions
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Female only
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
3
States / cities
Phoenix, Arizona • Miami, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aerobic Exercise for Concussion

NCT02959216
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Acute Brain Injury, Brain Concussion
Interventions
Aerobic Exercise, Stretching Exercise
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
13 Years to 18 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
3
States / cities
Boston, Massachusetts • Buffalo, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

RECOVER-ENERGIZE Platform Protocol

NCT06404047
View directory record Official record
Conditions
Long COVID, Long Covid19, Long Covid-19
Interventions
Personalized Cardiopulmonary Rehabilitation, Structured Pacing, Education, Usual Care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
42
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 33 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional Results available

The Effects of a Sub-maximal Exercise Program on Adolescents Who Sustained a Concussion

NCT03170856
View directory record Official record
Conditions
Concussion, Mild, Concussion, Brain, Concussion, Severe, Exertion; Excess
Interventions
Sub-maximal exercise
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 21 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Phase 4 Interventional Results available

Effects of Ranolazine and Exercise on Daily Physical Activity Trial

NCT01948310
View directory record Official record
Conditions
Chronic Stable Angina
Interventions
Ranolazine, Aerobic Exercise, Placebo
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 11, 2017 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Phase 4 Interventional Results available

The Back Pain Consortium Research Program Study

NCT04870957
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
PainGuide, MBSR, PT and exercise, Self -administered acupressure, Duloxetine, Pro-Diary monitor
Behavioral · Device · Drug
Lead sponsor
University of Michigan
Other
Eligibility
25 Years to 70 Years
Enrollment
494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 15, 2026, 10:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Treatment Optimization of Brain-injured Warfighters

NCT06561100
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Sub-symptomatic Adaptable Exercise Treatment (SAET), Stretching Control Group (SCG)
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 55 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Camp Pendleton, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 15, 2026, 10:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

NCT05320822
View directory record Official record
Conditions
Concussion, Brain
Interventions
Active Rehab (Group 2), Progressive Return to Activity (Group 1)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Fort Liberty, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 15, 2026, 10:26 AM EDT
Not listed Not applicable Interventional

The Effect of a Sub-symptom Threshold Aerobic Exercise Program on Recovery in Concussed Athletes

NCT03865433
View directory record Official record
Conditions
Concussion, Mild, Rehabilitation
Interventions
Aerobic Exercise, Placebo/Stretching
Other
Lead sponsor
Rocky Mountain University of Health Professions
Other
Eligibility
13 Years to 17 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 15, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Study of an Exercise Program (STEP) for Youth With Concussion

NCT02673112
View directory record Official record
Conditions
Persistent Concussion Symptoms
Interventions
Subthreshold exercise (STEP) with mobile health coaching, Light stretching (LS)
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 25, 2018 · Synced Sep 15, 2026, 10:26 AM EDT