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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:24 PM EDT

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Showing 529–552 of 1,844 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Supplementation Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effects Fortified Nutritional Supplementation on Childhood Cognition

NCT02630667
View directory record Official record
Conditions
Cognitive Ability, General, Dietary Modification
Interventions
SLOW Carbohydrate, MEDIUM Carbohydrate, FAST Carbohydrate
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
9 Years to 10 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 21, 2026, 5:24 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

The Effect of NAD Supplementation on Brain Vascular Health in Aging

NCT05483465
View directory record Official record
Conditions
Aging
Interventions
Nicotinamide riboside, Placebo
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
60 Years to 85 Years
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 21, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial

NCT06565052
View directory record Official record
Conditions
Rectal Cancer, Colorectal Cancer, Rectal Cancer Stage II, Rectal Cancer Stage III
Interventions
Prehabilitation Program
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Gojiberry Intake (Lycium Barbarium) on Macular Function

NCT03983525
View directory record Official record
Conditions
Macular Pigment Optical Density
Interventions
Goji berry, Lutein + zeaxanthin supplementation
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
45 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2020 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Phase 3 Interventional

Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.

NCT04549116
View directory record Official record
Conditions
Infertility
Interventions
Progesterone-IBSA Injectable Solution, Progesterone Vaginal Gel with Applicator, Placebo Vaginal gel with applicator, Placebo injectable solution
Drug
Lead sponsor
IBSA Institut Biochimique SA
Industry
Eligibility
35 Years to 42 Years · Female only
Enrollment
688 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
24
States / cities
Tempe, Arizona • Encino, California • Los Angeles, California + 20 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 21, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ACEs, SIRT1, and Premature Vascular Aging in Humans

NCT07073352
View directory record Official record
Conditions
Adverse Childhood Experiences, Endothelial Dysfunction
Interventions
Nicotinamide Riboside, Placebo
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Iowa City, Iowa • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of 4 Weeks of Citrulline and Glutathione Supplementation on Arterial Function

NCT04672447
View directory record Official record
Conditions
Menopause, Cardiovascular Risk Factor
Interventions
L-Citrulline, Placebo, Glutathione
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
50 Years to 79 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Phase 2 Interventional Results available

Nitrite Supplementation in Long COVID Patients

NCT05618574
View directory record Official record
Conditions
Long COVID, Cardiorespiratory Fitness
Interventions
140 ml per day of Beet-It nitrate beverage (James White Drinks Ltd., Ipswich, UK), 210 ml of nitrate-depleted placebo
Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Nutritional Supplement Capsule Containing Curcumin, Green Tea Extract, Polygonum Cuspidatum Extract, and Soybean Extract in Healthy Participants

NCT00768118
View directory record Official record
Conditions
Healthy, no Evidence of Disease
Interventions
curcumin/green tea extract/Polygonum cuspidatum extract/soybean extract capsule, electrophoretic mobility shift assay, laboratory biomarker analysis
Dietary Supplement · Genetic · Other
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 23, 2014 · Synced Oct 21, 2026, 5:24 PM EDT
Terminated Phase 1 Interventional

Vitamin D3 (Vit D3) Supplementation and T Cell Immunomodulation in Patients With Newly Diagnosed Operative Invasive Ductal Breast Carcinoma

NCT01816555
View directory record Official record
Conditions
Newly Diagnosed Operative Invasive Ductal Breast Carcinoma Stage I-II
Interventions
Vitamin D
Dietary Supplement
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2015 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Dietary Supplementation in Heart Failure

NCT03980574
View directory record Official record
Conditions
Heart Failure
Interventions
R Drink
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 22, 2021 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of NMN Supplementation on Organ System Biology

NCT04571008
View directory record Official record
Conditions
Glucose Metabolism Disorders
Interventions
Placebo, Treatment
Other · Dietary Supplement
Lead sponsor
Washington University School of Medicine
Other
Eligibility
45 Years to 75 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 21, 2026, 5:24 PM EDT
Withdrawn Phase 3 Interventional

Efficacy of Coenzyme Q10 Supplementation on Multi-Organ Dysfunction in Severely Burned Patients

NCT03968640
View directory record Official record
Conditions
Multiple Organ Failure
Interventions
CoQ10, Placebo
Dietary Supplement
Lead sponsor
American Burn Association
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese Adolescents

NCT00858247
View directory record Official record
Conditions
Obesity
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Phase 2 Interventional

Lactobacillus Johnsonii Supplementation in Adults With T1D

NCT03961347
View directory record Official record
Conditions
Type 1 Diabetes (T1D)
Interventions
L. johnsonii Probiotic, Placebo Capsule
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 45 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 21, 2026, 5:24 PM EDT
Terminated Phase 2 Interventional Results available

Genistein Supplementation to Mitigate Cardiometabolic Dysfunction in Patients Undergoing Androgen Deprivation Therapy for Prostate Cancer

NCT02766478
View directory record Official record
Conditions
Prostate Cancer
Interventions
Genistein, Placebo
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Oct 21, 2026, 5:24 PM EDT
Terminated Phase 4 Interventional Results available

Pancreatic Enzyme Supplementation for Celiac Disease

NCT02475369
View directory record Official record
Conditions
Celiac Disease
Interventions
pancrelipase
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Oct 21, 2026, 5:24 PM EDT
Terminated Phase 4 Interventional Results available

Vitamin D Deficiency in Patients With Hypertension

NCT00974922
View directory record Official record
Conditions
Vitamin D Deficiency, Hypertension
Interventions
Aliskiren, Cholecalciferol, Placebo
Drug · Dietary Supplement
Lead sponsor
UConn Health
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 21, 2026, 5:24 PM EDT
Terminated No phase listed Observational

Quality Improvement Program (QIP) to Reduce 30-Day Readmission in Malnourished Hospitalized Patients

NCT02262429
View directory record Official record
Conditions
Malnutrition
Interventions
ONS QIP, ONS Standard Feeding
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
18 Years and older
Enrollment
2,386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
4
States / cities
Barrington, Illinois • Libertyville, Illinois • Oak Lawn, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Oct 21, 2026, 5:24 PM EDT
Not listed Not applicable Interventional

Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies

NCT03682029
View directory record Official record
Conditions
Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia-1, Cytopenia
Interventions
Vitamin C (ascorbic acid), Placebo
Dietary Supplement · Other
Lead sponsor
Copenhagen University Hospital, Rigshospitalet
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States

NCT06309914
View directory record Official record
Conditions
Mental Processes, Cognitive Change, Mood Change
Interventions
Placebo, Enovita Grape Seed Extract, Mirtoselect Bilberry Extract, Virtiva Plus Ginko Biloba Extract
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
25 Years to 55 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Oct 21, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Carbohydrates Versus Carbohydrates + Protein on Resistance Training Outcomes

NCT07600138
View directory record Official record
Conditions
Muscle Hypertrophy, Strength
Interventions
CHO, PRO
Dietary Supplement
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 21, 2026, 5:24 PM EDT
Terminated Phase 2 Interventional Results available

Trial of Oral Glutamine in Patients With Sickle Cell Anemia

NCT00131508
View directory record Official record
Conditions
Anemia, Sickle Cell
Interventions
Glutamine, Placebo
Drug
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Oct 21, 2026, 5:24 PM EDT
Recruiting No phase listed Observational

Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

NCT06009276
View directory record Official record
Conditions
Heart Failure, Systolic, Heart Failure, Diastolic, Peripheral Arterial Disease, Overweight and Obesity
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
70 participants
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 21, 2026, 5:24 PM EDT