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ClinicalTrials.gov public records Last synced Oct 5, 2026, 4:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 1,072 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Surgical Implantation Clear all
Completed Not applicable Interventional

Pivotal IDE Study of the BRYAN(R) Cervical Disc Prosthesis in the Treatment of DDD Versus ACDF

NCT00437190
View directory record Official record
Conditions
Radiculopathy, Myelopathy, Cervical Degenerative Disc Disease
Interventions
ATLANTIS™ Cervical Plate System and allograft, BRYAN Cervical Disc Prosthesis
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
21 Years and older
Enrollment
494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2016
U.S. locations
38
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Campbell, California + 31 more
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Propel Nova Sinus Implant in Peripheral Sinus Ostia

NCT02228720
View directory record Official record
Conditions
Chronic Sinusitis
Interventions
Propel Nova Sinus Implant
Device
Lead sponsor
Intersect ENT
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Miami, Florida • Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 4, 2017 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Phase 3 Interventional Results available

RNS® System Pivotal Study

NCT00264810
View directory record Official record
Conditions
Epilepsy
Interventions
RNS® System implantation, RNS® System responsive stimulation
Procedure · Device
Lead sponsor
NeuroPace
Industry
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
32
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2013 · Synced Oct 5, 2026, 4:22 PM EDT
Recruiting Not applicable Interventional

MASA Valve Early Feasibility Study

NCT05452720
View directory record Official record
Conditions
Tetrology of Fallot, Pulmonary Stenosis, Truncus Arteriosus, Transposition of Great Vessels, Pulmonary Atresia, Ross Procedure
Interventions
Surgical Right Ventricular Outflow Tract Reconstruction
Device
Lead sponsor
PECA Labs
Industry
Eligibility
0 Years to 22 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
5
States / cities
Peoria, Illinois • Boston, Massachusetts • Cincinnati, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2024 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Phase 2Phase 3 Interventional

TAXUS IV-SR: Treatment of De Novo Coronary Disease Using a Single Paclitaxel-Eluting Stent

NCT00292474
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
percutaneous coronary intervention
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
1,326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2008 · Synced Oct 5, 2026, 4:22 PM EDT
Recruiting Not applicable Interventional

Clinical Utility of Residual Hearing in the Cochlear Implant Ear

NCT04707885
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Hearing Loss, Bilateral
Interventions
Electrocochleography
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 79 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
5
States / cities
Rochester, Minnesota • St Louis, Missouri • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Phase 4 Interventional

A Comparison of Subvastus and Midvastus Approaches in Minimally-Invasive Total Knee Arthroplasty

NCT00848133
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
mini-midvastus surgical approach for total knee arthroplasty, mini-subvastus surgical approach for total knee arthroplasty
Procedure
Lead sponsor
Sinai Hospital of Baltimore
Other
Eligibility
40 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Effingham, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 20, 2009 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Phase 3 Interventional

MAVERICK™ Total Disc Replacement- Pivotal Study

NCT00635843
View directory record Official record
Conditions
Spinal Diseases
Interventions
MAVERICK™ Disc, LT-CAGE® Lumbar Tapered Fusion Device and INFUSE® Bone Graft
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years to 70 Years
Enrollment
577 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
32
States / cities
Huntsville, Alabama • Daly City, California • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2013 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Not applicable Interventional

Clinical Study of Cochlear Implants in Adults With Asymmetrical Hearing Loss

NCT02004535
View directory record Official record
Conditions
Hearing Loss
Interventions
Cochlear Implantation
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 5, 2026, 4:22 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft

NCT04550689
View directory record Official record
Conditions
Tooth Loss
Interventions
Bone graft
Device
Lead sponsor
UConn Health
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 5, 2026, 4:22 PM EDT
Completed No phase listed Observational

Extension Phase of the Chronicle® Offers Management to Patients With Advanced Signs & Symptoms of Heart Failure Study

NCT00991120
View directory record Official record
Conditions
Heart Failure
Interventions
Chronicle Implantable Hemodynamic Monitor (IHM) System, Chronicle Implantable Cardioverter Defibrillator (ICD)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
19
States / cities
Birmingham, Alabama • Springfield, Illinois • Fort Wayne, Indiana + 16 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2017 · Synced Oct 5, 2026, 4:22 PM EDT
Terminated Not applicable Interventional Results available

Computer-Assisted Fixation of Trochanteric Femur Fractures

NCT04528459
View directory record Official record
Conditions
Hip Fractures
Interventions
Stryker© ADAPT™ platform, Traditional fluoroscopy
Device · Radiation
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Oct 5, 2026, 4:22 PM EDT
Active, not recruiting Not applicable Interventional

Zimmer Trabecular Metal Total Ankle PMCF

NCT02038140
View directory record Official record
Conditions
Degenerative Arthritis, Rheumatoid Arthritis, Post Traumatic Arthritis
Interventions
Zimmer Trabecular Metal Total Ankle System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
5
States / cities
Sacramento, California • Grand Rapids, Michigan • Charlotte, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Not applicable Interventional Results available

Zenith® p-Branch® and Zenith® Fenestrated AAA Endovascular Graft Clinical Study

NCT01652235
View directory record Official record
Conditions
Aortic Aneurysm, Abdominal
Interventions
Zenith® p-Branch® or Zenith® Fenestrated AAA Endovascular Graft
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2023
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 5, 2026, 4:22 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Pain Management After Shoulder Arthroplasty

NCT04872270
View directory record Official record
Conditions
Caffeine, Pain, Joint
Interventions
Total Shoulder Arthroplasty, Caffeine Pill, Percocet 10Mg-325Mg Tablet, Zofran 4Mg Tablet
Procedure · Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
55 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2021 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Not applicable Interventional Results available

Use of Real Time Instrumentation (RTI) in Total Shoulder Arthroplasty

NCT01905241
View directory record Official record
Conditions
Anatomic Total Shoulder Arthroplasty
Interventions
Anatomic TSA using RTI, Anatomic Total Shoulder Arthroplasty
Device · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 5, 2026, 4:22 PM EDT
Active, not recruiting Phase 3 Interventional

A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DME

NCT04108156
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
PDS Implant Pre-Filled with 100 mg/mL Ranibizumab, Intravitreal Ranibizumab 0.5 mg Injection, Ranibizumab refill exchange
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
672 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
88
States / cities
Mesa, Arizona • Phoenix, Arizona • Bakersfield, California + 79 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adjunct Study of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants

NCT00691327
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Natrelle(TM) Silicone-Filled Breast Implants
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
Female only
Enrollment
84,329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 13, 2014 · Synced Oct 5, 2026, 4:22 PM EDT
Active, not recruiting Phase 3 Interventional

NOVOCART®3D for Treatment of Articular Cartilage of the Knee

NCT01957722
View directory record Official record
Conditions
Articular Cartilage of the Femoral Condyle Between 2-6cm2
Interventions
Microfracture, NOVOCART 3D
Procedure · Biological
Lead sponsor
Aesculap Biologics, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2027
U.S. locations
30
States / cities
La Mesa, California • Los Angeles, California • Redwood City, California + 26 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 5, 2026, 4:22 PM EDT
Terminated No phase listed Observational

Curvafix® Intramedullary System for Fixation of Pelvic and Acetabular Fractures, A Post Market Evaluation

NCT05606042
View directory record Official record
Conditions
Pelvic Ring Fracture, Acetabular Fracture, Pelvic Fracture, Pelvic Fracture Acetabulum
Interventions
IM Implant
Device
Lead sponsor
CurvaFix, Inc.
Industry
Eligibility
Not listed
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
6
States / cities
Springfield, Illinois • Columbia, Missouri • Columbus, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 5, 2026, 4:22 PM EDT
Completed Phase 2 Interventional Results available

Efficacy, Safety and Pharmacokinetic Profile of a Collagen Bupivacaine Implant in Men After Open Mesh Herniorrhaphy

NCT00626886
View directory record Official record
Conditions
Postoperative Pain, Inguinal Hernia
Interventions
Bupivacaine Collagen Sponge, placebo collagen sponge
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years and older · Male only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 5, 2026, 4:22 PM EDT
Terminated Not applicable Interventional Results available

Propaten Randomized Investigation on Cost-benefit and Efficacy

NCT01601873
View directory record Official record
Conditions
End-stage Renal Disease
Interventions
PROPATEN, Standard Graft
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
5
States / cities
Little Rock, Arkansas • New Orleans, Louisiana • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2019 · Synced Oct 5, 2026, 4:22 PM EDT
Recruiting No phase listed Observational

Microbiome Population Adaptation Study

NCT06310239
View directory record Official record
Conditions
Amputation With Osseointegration
Interventions
Collection of biologic samples and data
Other
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 5, 2026, 4:22 PM EDT
Completed No phase listed Observational

A Retrospective Study to Evaluate the ConforMIS iUni, iDuo & iTotal® KRS

NCT03152357
View directory record Official record
Conditions
Osteoarthritis, Knee, Knee Osteoarthritis
Interventions
ConforMIS iUni, iDuo, or iTotal (CR)
Device
Lead sponsor
Restor3D
Industry
Eligibility
18 Years and older
Enrollment
950 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boynton Beach, Florida
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Oct 5, 2026, 4:22 PM EDT