Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 6, 2026, 4:32 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: TAVR Device Clear all

Conditions: Severe Symptomatic Calcified Native Aortic Valve Stenosis
Interventions: Cerebral Protection System-The SENTINEL System with TAVR, TAVR; Device
Lead sponsor: Claret Medical; Industry
Eligibility: 18 Years and older
Enrollment: 363 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 14
States / cities: Los Angeles, California • Washington D.C., District of Columbia • Clearwater, Florida + 9 more

Conditions: Symptomatic Severe Native Aortic Stenosis, Aortic Stenosis
Interventions: TAVR Device, Siegel TAVR Device; Device
Lead sponsor: MiRus; Industry
Eligibility: 18 Years and older
Enrollment: 1,025 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Aortic Stenosis Treated With TAVI, Aortic Diseases
Interventions: F2 Filter and Delivery System, Transcatheter Aortic Valve Replacement (TAVR); Device · Procedure
Lead sponsor: EnCompass Technologies, Inc.; Industry
Eligibility: 21 Years to 90 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 8
States / cities: Naples, Florida • Indianappolis, Indiana • Detroit, Michigan + 5 more

Conditions: Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency, Aortic Valve Disease
Interventions: JenaValve Trilogy Heart Valve System; Device
Lead sponsor: JenaValve Technology, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 30
States / cities: Tucson, Arizona • Los Angeles, California • San Diego, California + 25 more

Conditions: Aortic Stenosis
Interventions: Prehabilitation, Usual Care; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 60 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Aortic Stenosis
Interventions: Aortic Stenosis; Device
Lead sponsor: EnCompass Technologies, Inc.; Industry
Eligibility: 22 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Severe Aortic Stenosis, Cardiogenic Shock, Cardiogenic Shock, ECMO, Trans-catheter Aortic Valve Implantation
Interventions: Left Atrial Veno-Arterial Extracorporeal Membrane Oxygenation (LAVA-ECMO); Device
Lead sponsor: Atlantic Health System; Other
Eligibility: 18 Years to 100 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Detroit, Michigan • Morristown, New Jersey

Conditions: Embolism
Interventions: Emboliner Embolic Protection, Sentinel Cerebral Protection; Device
Lead sponsor: Emboline; Industry
Eligibility: 18 Years and older
Enrollment: 540 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: New York, New York • Tulsa, Oklahoma

Conditions: Aortic Valve Stenosis
Interventions: Not listed
Lead sponsor: HemoCept Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Aortic Valve Stenosis, Aortic Stenosis, Aortic Valve Disease
Interventions: EmStop Embolic Protection System, Boston Scientific Sentinel; Device
Lead sponsor: EmStop Inc; Industry
Eligibility: 22 Years and older
Enrollment: 663 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 7
States / cities: Thousand Oaks, California • Clearwater, Florida • New Orleans, Louisiana + 4 more

Conditions: Aortic Valve Stenosis
Interventions: V8 Balloon Aortic Valvuloplasty (BAV) Catheter; Device
Lead sponsor: InterValve, Inc.; Industry
Eligibility: Not listed
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 7
States / cities: Los Angeles, California • Minneapolis, Minnesota • Nashville, Tennessee + 2 more

Conditions: Bicuspid Aortic Valve Disease
Interventions: Transcatheter Aortic Valve Replacement, the open chest surgery to replace the aortic valve; Procedure
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 50 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2040
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Aortic Stenosis, Heart Block, Aortic Insufficiency
Interventions: Electrophysiology Study; Diagnostic Test
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Arterial Occlusion, Cardiovascular Diseases, Hematoma
Interventions: Perclose, Statseal; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Aortic Valve Stenosis, Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Valve Replacement
Interventions: EMBLOK™ Embolic Protection System ("EMBLOK EPS"), SENTINEL™ Cerebral Protection System; Device
Lead sponsor: Emblok, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 532 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 23
States / cities: Chandler, Arizona • Orange, California • Sacramento, California + 20 more

Conditions: Atrial Fibrillation, Aortic Valve Stenosis
Interventions: WATCHMAN, TAVR; Device
Lead sponsor: samir kapadia; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 32
States / cities: Phoenix, Arizona • Burlingame, California • Santa Barbara, California + 27 more

Conditions: Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Regurgitation
Interventions: J-Valve TF System; Device
Lead sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC; Industry
Eligibility: Not listed
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 9
States / cities: Scottsdale, Arizona • Washington D.C., District of Columbia • Oak Lawn, Illinois + 6 more

Conditions: Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency
Interventions: Transcatheter Aortic Valve Replacement (TAVR) using Trilogy THV System, SAVR; Device
Lead sponsor: JenaValve Technology, Inc.; Industry
Eligibility: Not listed
Enrollment: 1,016 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2036
U.S. locations: 40
States / cities: Burlingame, California • La Jolla, California • Los Angeles, California + 32 more

Conditions: Native and Valve in Valve Aortic Valve Failure
Interventions: ASHI_INTECC Astato XS 20 0.014 guidewire; Device
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 21 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 4
States / cities: Washington D.C., District of Columbia • Atlanta, Georgia • Detroit, Michigan + 1 more

Conditions: Transcatheter Aortic Valve Replacement
Interventions: Single Perclose Pro vascular closure device, Dual Perclose vascular closure device; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Aortic Valve Regurgitation, Aortic Valve Disease Mixed
Interventions: J-Valve Transfemoral (TF) System; Device
Lead sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC; Industry
Eligibility: 18 Years and older
Enrollment: 194 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2032
U.S. locations: 35
States / cities: Phoenix, Arizona • Scottsdale, Arizona • La Jolla, California + 27 more

Conditions: Aortic Stenosis
Interventions: ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: Not listed
Enrollment: 1,948 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2029
U.S. locations: 69
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 58 more

Conditions: Aortic Valve Disease
Interventions: VIV TAVR with BVF using TCEP; Device
Lead sponsor: Saint Luke's Health System; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Severe Aortic Valve Stenosis
Interventions: ProtEmbo - Cerebral Embolic Protection, Sentinel - Cerebral Embolic Protection; Device
Lead sponsor: Protembis GmbH; Industry
Eligibility: 18 Years and older
Enrollment: 284 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 15
States / cities: Tucson, Arizona • Los Angeles, California • Clearwater, Florida + 9 more

Search by objective public record fields.

Cerebral Protection in Transcatheter Aortic Valve Replacement

STAR Trial (Siegel Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis)

Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR

The JenaValve ALIGN-AR Pivotal Trial

Prehabilitation to Improve Functional and Clinical Outcomes in Patients With Aortic Stenosis

U.S. Multicenter Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR

Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR

Protect the Head to Head Study

Detecting Changes in Arterial Blood Volume and Cardiac Efficiency

CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material

Post-Market Surveillance Registry to Monitor Performance and Safety of V8 Device

TAVR vs SAVR in Severe Bicuspid Aortic Stenosis

Conduction Disease After Transcatheter Aortic Valve Replacement

Comparing Perclose to Statseal With Perclose in Transcatheter Aortic Valve Replacement Arteriotomy Closure

Evaluation of Safety and Effectiveness of the EMBLOK EPS During TAVR

WATCH-TAVR, WATCHMAN for Patients With Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement

J-Valve TF Early Feasibility Study

ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation

Comparison of Single vs. Dual Perclose Devices for Large-Bore Access Closure in TAVR

J-Valve Transfemoral Pivotal Study

ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement

Quantification of Debris Captured Using TCEP During VIV TAVR With BVF

The PROTEMBO Trial