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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:06 PM EDT

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Showing 409–432 of 1,612 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: THRIVE Clear all
Completed No phase listed Observational Accepts healthy volunteers

CSD201004: An Actual Use Study of P10 and P13 Nicotine Pouches Among U.S. Adult Smokers

NCT05184920
View directory record Official record
Conditions
Smoking, Tobacco Use, Tobacco Smoking
Interventions
P1012919 nicotine pouch, P1012915 nicotine pouch, P1012914 nicotine pouch, P1013315 nicotine pouch, P1013119 nicotine pouch, P1013218 nicotine pouch, P1012818 nicotine pouch, P1312915 nicotine pouch, P1312914 nicotine pouch, P1313015 nicotine pouch, P1313314 nicotine pouch, P1312815 nicotine pouch
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
1,105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
10
States / cities
Phoenix, Arizona • Atlanta, Georgia • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional

Effects of Creatine Supplementation in Breast Cancer Survivors

NCT04207359
View directory record Official record
Conditions
Breast Cancer, Chemotherapy Effect, Muscle Weakness, Muscle Loss, Exercise
Interventions
Creatine
Dietary Supplement
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 20, 2026, 2:06 PM EDT
Active, not recruiting Not applicable Interventional

A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities

NCT05671380
View directory record Official record
Conditions
Tobacco Use Cessation, Cardiovascular Diseases, Tobacco Use, Smoking, Smoking Cessation
Interventions
Longitudinal Proactive Outreach (LPO)., Ask-Advice-Connect (AAC)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Minneapolis, Minnesota • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Nicotine Treatment for Pulmonary Sarcoidosis: A Clinical Trial Pilot Study

NCT02265874
View directory record Official record
Conditions
Sarcoidosis
Interventions
Habitrol, Placebo to Habitrol
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 20, 2026, 2:06 PM EDT
Recruiting Phase 2 Interventional

Informing Oral Nicotine Pouch Regulations to Promote Public Health

NCT06315881
View directory record Official record
Conditions
Tobacco-Related Carcinoma
Interventions
Biospecimen Collection, Cigarette, Nicotine Oral Pouch, Smokeless Tobacco, Survey Administration, Text Message-Based Navigation Intervention
Procedure · Drug · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 20, 2026, 2:06 PM EDT
Terminated Phase 1 Interventional

Early Tobacco Abstinence - 5

NCT00224965
View directory record Official record
Conditions
Tobacco Use
Interventions
Behavior Therapy
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 60 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2004
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 20, 2026, 2:06 PM EDT
Not yet recruiting No phase listed Observational

GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study

NCT07588984
View directory record Official record
Conditions
Obesity & Overweight, Weight Loss, Preventative Health, Body Weight, Cardiovascular Disease Risk Factor
Interventions
Noom Weight, Free Tier, Education-only control, Semaglutide, Tirzepatide, Microdose semaglutide, Microdose tirzepatide
Behavioral · Drug
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
2,310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 20, 2026, 2:06 PM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream

NCT06334016
View directory record Official record
Conditions
Cannabis Dependence
Interventions
Biospecimen Collection, Cannabis sativa Extract, Nicotine, Placebo Administration, Questionnaire Administration
Procedure · Drug · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional

Intensive Intervention for Smokers - 6

NCT00217984
View directory record Official record
Conditions
Tobacco Use Disorder, Alcohol Dependence
Interventions
Usual Care, Extended cognitive behavior therapy
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional

Feasibility and Acceptability of Switching to E-cigarettes Among Cigarette Smokers Engaged in SUD Treatment

NCT05918887
View directory record Official record
Conditions
Tobacco Dependence Caused by Cigarettes
Interventions
NJOY ACE commercial e-cigarette
Device
Lead sponsor
University of Nevada, Reno
Other
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Flu Shot Pre-visit Questionnaire

NCT05508698
View directory record Official record
Conditions
Influenza
Interventions
Precommitment Nudge, Salience
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
230,962 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional Results available

Nicotine and Behavior in Adult ADHD

NCT00573248
View directory record Official record
Conditions
ADHD
Interventions
Nicotine, Placebo
Drug · Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 45 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2011 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Teaching Healthy Responsive Parenting During Infancy to Promote Vital Growth and dEvelopment (THRIVE) Study

NCT04989738
View directory record Official record
Conditions
Parenting, Feeding Behavior, Sleep, Parent-Child Relations
Interventions
THRIVE intervention, Active Control
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
0 Weeks to 4 Weeks
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Oct 20, 2026, 2:06 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

NCT03745339
View directory record Official record
Conditions
Opioid-Related Disorders, Drug Addiction
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
21 Years to 60 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional

A Study of Tobacco Smoke and Children With Respiratory Illnesses

NCT03062709
View directory record Official record
Conditions
Bronchiolitis, Pneumonia, Reactive Airway Disease, Asthma, Tobacco Smoking, Tobacco Cessation, Bronchopulmonary Dysplasia
Interventions
Breathe Easy Coalition written materials, Maine Tobacco Helpline, Urine cotinine testing
Behavioral · Diagnostic Test
Lead sponsor
MaineHealth
Other
Eligibility
Up to 10 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional

Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking Cessation

NCT04839198
View directory record Official record
Conditions
Smoking Cessation
Interventions
Android Wear smartwatch, Adaptive Treatment, Nicotine Patch, interviewing-based counseling
Behavioral · Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Phase 2 Interventional Results available

Adaptive Pharmacotherapy for Smoking Cessation

NCT02501265
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Varenicline Standard Protocol, Nicotine Patch Standard Protocol, Varenicline Adaptive Protocol, Nicotine Adaptive Protocol
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2021 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Efficacy and Safety of CTP-543 in Adults With Moderate to Severe Alopecia Areata (THRIVE-AA1)

NCT04518995
View directory record Official record
Conditions
Alopecia Areata
Interventions
CTP-543 matching placebo, CTP-543
Drug
Lead sponsor
Concert Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
706 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
47
States / cities
Birmingham, Alabama • Bakersfield, California • Encinitas, California + 40 more
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Phase 4 Interventional Results available

Integrating Financial Management Counseling and Smoking Cessation Counseling to Reduce Health and Economic Disparities in Low-Income Immigrants

NCT03187730
View directory record Official record
Conditions
Smoking Cessation
Interventions
Integrated Smoking Cessation and Financial Counseling, Waitlist Integrated Smoking Cessation and Financial Counseling, Nicotine Replacement Therapy (NRT)
Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 20, 2026, 2:06 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Ask Advise Connect (AAC) Harris Heath CPRIT

NCT01788787
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Quitline-Delivered Proactive Telephone Counseling, Follow-Up Phone Call, Smoking Cessation Training, Qualitative Interviews Concerning the Implementation of AAC
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
5,212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2049
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2019 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Phase 3 Interventional Results available

Study to Determine the Efficacy and Safety of a Novel Nicotine Replacement Therapy

NCT02355665
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Nicotine Spray, Placebo
Drug
Lead sponsor
McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
1,198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
8
States / cities
Scottsdale, Arizona • Burbank, California • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate Nicotine Uptake and Biomarkers in Smokers Using mybluTM Electronic Cigarettes

NCT04430634
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Myblu variant A, Myblu variant B, Myblu variant C, Myblu variant D, Myblu variant E, Myblu variant F, Myblu variant G, Myblu variant H
Other
Lead sponsor
Fontem US LLC
Industry
Eligibility
21 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 7, 2021 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging

NCT01664741
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Nicotine patch - transdermal, placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 60 Years
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Oct 20, 2026, 2:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Interventions to Increase Parent Adherence With Behavior Plans

NCT05238766
View directory record Official record
Conditions
Family Accommodation, Nonadherence, Behavior Problem
Interventions
DEAL
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland • Columbia, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 20, 2026, 2:06 PM EDT