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Conditions: Chronic Disease
Interventions: MY-Skills Mobile; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 65 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: cisplatin, everolimus, gene expression analysis, immunohistochemistry staining method, laboratory biomarker analysis, pharmacological study, biopsy; Drug · Genetic · Other + 1 more
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: New York, New York

Conditions: Prostate Cancer, Advanced Prostate Cancer, Hormone Sensitive Prostate Cancer
Interventions: Darolutamide, Relugolix; Drug
Lead sponsor: Atish Choudhury, MD; Other
Eligibility: 18 Years and older · Male only
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 3
States / cities: Boston, Massachusetts

Conditions: Multiple Sclerosis
Interventions: DirectCAM, TeleCAM, rDirectCAM; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 70 Years
Enrollment: 911 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 40
States / cities: Athens, Alabama • Bessemer, Alabama • Birmingham, Alabama + 37 more

Conditions: Hepatic Impairment
Interventions: Hydrocodone bitartrate extended-release tablet; Drug
Lead sponsor: Cephalon; Industry
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Multiple Sclerosis
Interventions: Functional Balance Intervention, Stretching; Behavioral
Lead sponsor: University of Illinois at Chicago; Other
Eligibility: 18 Years to 90 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Human Immunodeficiency Virus, HIV Seropositivity
Interventions: iTransition; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 3
States / cities: Atlanta, Georgia • Philadelphia, Pennsylvania

Conditions: Psychotic Disorders
Interventions: BI 409306, Placebo; Drug
Lead sponsor: Boehringer Ingelheim; Industry
Eligibility: 16 Years to 30 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 23
States / cities: Culver City, California • San Diego, California • New Haven, Connecticut + 19 more

Conditions: Breast Cancer, Stage III Breast Cancer, Breast Cancer Female, Stage I Breast Cancer, Stage II Breast Cancer
Interventions: THRIVE, Health Education Support Program; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 65 Years and older · Female only
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 4
States / cities: Boston, Massachusetts • Cleveland, Ohio • Pittsburgh, Pennsylvania + 1 more

Conditions: Atherosclerosis, Percutaneous Coronary Intervention, Acute Coronary Syndrome
Interventions: cangrelor P2Y12 (platelet) inhibitor, Clopidogrel - 300 or 600 mg (study arm), Clopidogrel 600 mg post cangrelor; Drug
Lead sponsor: The Medicines Company; Industry
Eligibility: 18 Years and older
Enrollment: 11,145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Anderson, South Carolina

Conditions: Malignant Neoplasm of Breast
Interventions: Mind-Body Exercises, Questionnaires; Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: HCV Infection
Interventions: ABT-333, ketoconazole, placebo; Drug
Lead sponsor: Abbott; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2008
U.S. locations: 1
States / cities: Waukegan, Illinois

Conditions: HIV Infections, Malaria
Interventions: lopinavir/ritonavir, efavirenz, artemether/lumefantrine; Drug
Lead sponsor: Fran Aweeka; Other
Eligibility: 21 Years to 60 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Healthy Volunteers
Interventions: Placebo, PF-07258669; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 60 Years to 89 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 10
States / cities: Birmingham, Alabama • Atlantis, Florida • Bradenton, Florida + 7 more

Conditions: Depressive Disorder, Depression, Depressive Disorder, Major, Mood Disorders, Mental Disorders
Interventions: OPC-34712 + ADT, Placebo + ADT; Drug
Lead sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 826 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 37
States / cities: Arcadia, California • Beverly Hills, California • Fresno, California + 34 more

Conditions: Traumatic Brain Injury
Interventions: Multivitamin Supplement intervention; Dietary Supplement
Lead sponsor: Amen Clinics, Inc.; Industry
Eligibility: 18 Years and older · Male only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Newport Beach, California

Conditions: Castration Levels of Testosterone, Castration-Resistant Prostate Carcinoma, PSA Progression, Stage IV Prostate Adenocarcinoma AJCC v7
Interventions: Apalutamide, Stereotactic Body Radiation Therapy; Drug · Radiation
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Male only
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Gastroesophageal Cancer
Interventions: Sacituzumab tirumotecan, Trifluridine-Tipiracil, Irinotecan, Paclitaxel, Docetaxel, Rescue medications, Supportive care measures; Biological · Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years and older
Enrollment: 473 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 17
States / cities: Gilbert, Arizona • Los Angeles, California • Orlando, Florida + 13 more

Conditions: Emotional Regulation, Problem Behavior, Irritable Mood
Interventions: Mightier Online Gameplay; Behavioral
Lead sponsor: Neuromotion Labs; Industry
Eligibility: 6 Years to 11 Years
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Malignant Lung Neoplasm
Interventions: Standard Follow-Up Care, Caregiver-Related Intervention or Procedure, Educational Intervention, Quality-of-Life Assessment, Questionnaire Administration; Procedure · Other
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 21 Years and older
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Duarte, California

Conditions: Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infection (STI), Alcohol and Drug Use
Interventions: Face-to-Face Young Women's CoOp (YWC), mHealth Young Women's CoOp (YWC), HIV Counseling and Testing; Behavioral
Lead sponsor: RTI International; Other
Eligibility: 18 Years to 25 Years · Female only
Enrollment: 652 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 4
States / cities: Durham, North Carolina • Greensboro, North Carolina • High Point, North Carolina + 1 more

Conditions: Prostate Cancer, Metastatic Prostate Cancer, Androgen Deprivation Therapy
Interventions: Telerehabilitation Intervention; Other
Lead sponsor: University of Utah; Other
Eligibility: 21 Years and older · Male only
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: COPD, Anxiety, Depression, Stress, Interstitial Lung Disease
Interventions: Sertraline, Placebo; Drug
Lead sponsor: Duke University; Other
Eligibility: 40 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Preeclampsia Postpartum
Interventions: Aspirin tablet, Placebo oral capsule; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: New York, New York

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A Mobile Intervention Merging Yoga and Self-Management Skills

Cisplatin and Everolimus in Treating Patients With Advanced Solid Tumors

Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and Darolutamide (CLEARED)

Tele-Exercise and Multiple Sclerosis

A Study to Evaluate the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Hepatic Function and Subjects With Moderate Hepatic Impairment

Functional Balance Intervention in Multiple Sclerosis

iTransition Development

This Study Tests Whether BI 409306 Prevents Patients With a Specific Type of Mental Illness (Attenuated Psychosis Syndrome) From Becoming Worse. This Study Looks at How Well Patients Tolerate the Medicine and How Effective it is Over 1 Year

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX)

An Early Stress-Reduction Intervention in Patients With Newly Diagnosed Breast Cancer

A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of ABT-333

Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug Combinations

A Study to Learn About the Study Medicine Called PF-07258669 in Older Adults Including Those at Risk of Malnutrition

Study of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Pyxis Trial)

Single Photon Emission Computed Tomography (SPECT) Imaging Study of Professional American Football Players

Apalutamide With or Without Stereotactic Body Radiation in Treating Castration-Resistant Prostate Cancer

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)

Examining the Impacts on In-School Behaviors of In-Home Videogame Play

Video-Assisted Intervention in Improving Recovery in Patients With Cancer Undergoing Lung Surgery and Caregivers

NC Young Women's CoOp

Impact of Multimodal Telerehabilitation in Rural Patients With Metastatic Prostate Cancer

Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD)

Postpartum Low-Dose Aspirin and Preeclampsia