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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Test Lens 2 Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses

NCT06377488
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Toric Contact Lens manufactured in Senofilcon A (C3) material with UV blocker / HEV filter
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
15
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Soft Contact Lens Use With 7 Day Extended Wear

NCT00597467
View directory record Official record
Conditions
Ametropia
Interventions
VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
23
States / cities
La Mesa, California • San Diego, California • Santa Monica, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating and Improving Functional Driving Vision of Patients With Astigmatism

NCT02624791
View directory record Official record
Conditions
Astigmatism
Interventions
1-DAY ACUVUE® MOIST contact lenses, 1-DAY ACUVUE® MOIST for ASTIGMATISM contact lenses, No contact lenses
Device · Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 39 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Contact Lenses With Experimental Dye on Visual Function

NCT03556579
View directory record Official record
Conditions
Ametropia
Interventions
senofilcon A with new UV blocker, senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Statesboro, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 17, 2019 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Evaluation of Daily Disposable Toric Soft Contact Lenses Manufactured With an Alternative Hydration Process

NCT05427539
View directory record Official record
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Jacksonville, Florida • Maitland, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2023 · Synced Sep 3, 2026, 6:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

NCT06034327
View directory record Official record
Conditions
Myopia, Juvenile Myopia, Myopia Progression
Interventions
Single vision, impact-resistant spectacle lenses; Test Arm, Single vision, impact-resistant spectacle lenses; Control Arm
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 8 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
14
States / cities
Oakland, California • San Diego, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2025 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Contact Lenses With New UV-blocker Manufactured With Different Techniques

NCT03475875
View directory record Official record
Conditions
Correction of Refraction Error, Attenuation of Bright Light
Interventions
senofilcon A TEST Lens, senofilcon A CONTROL Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
5
States / cities
Foster City, California • Jacksonville, Florida • Pickens, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over Two Weeks of Wear

NCT06161012
View directory record Official record
Conditions
Ocular Physiology
Interventions
Senofilcon A contact lenses (TEST), Delefilcon A contact lenses (CONTROL)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Granville, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Approved Contact Lenses

NCT02759692
View directory record Official record
Conditions
Visual Acuity
Interventions
TEST Contact Lens, CONTROL Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
283 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
13
States / cities
Montgomery, Alabama • Jacksonville, Florida • Sarasota, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Sep 3, 2026, 6:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Analyzing Retinal Microanatomy in ROP

NCT02887157
View directory record Official record
Conditions
Retinopathy of Prematurity, Neurodevelopmental Disorders, Macular Edema
Interventions
Swept Source OCT, Magnetic Resonance Imaging, Scavenged blood collection
Device · Other
Lead sponsor
Duke University
Other
Eligibility
30 Weeks and older
Enrollment
191 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
4
States / cities
Gainesville, Florida • St Louis, Missouri • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ocular Characteristics in Contact Lens and Spectacle Wear

NCT03913377
View directory record Official record
Conditions
Visual Acuity
Interventions
Spectacles, ACUVUE OASYS®1-Day with HydraLuxe™ Technology
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 42 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Jacksonville, Florida • Longwood, Florida • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses

NCT07076160
View directory record Official record
Conditions
Visual Acuity, Presbyopia
Interventions
INFUSE® One Day Multifocal, ACUVUE® OASYS MAX 1-Day Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
7
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Multifocal Toric Contact Lenses

NCT03208088
View directory record Official record
Conditions
Visual Acuity
Interventions
etafilcon A Investigational Toric Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
7
States / cities
Whittier, California • Orlando, Florida • Kahului, Hawaii + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear

NCT01015768
View directory record Official record
Conditions
Contact Lens-induced Corneal Fluorescein Staining
Interventions
ReNu Multiplus multipurpose disinfecting solution, Control
Device
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses

NCT05763628
View directory record Official record
Conditions
Presbyopia
Interventions
Control Lens (stenfilcon A), Test Lens (senofilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Vestal, New York • Athens, Ohio • Bellaire, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2024 · Synced Sep 3, 2026, 6:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mobility Performance in Daily Activities Among Children Wearing Spectacle Lenses

NCT07229352
View directory record Official record
Conditions
Myopia, Myopia Progression, Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 12 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Glendale, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Reusable Soft Contact Lenses

NCT06119191
View directory record Official record
Conditions
Myopia
Interventions
Control Lenses (comfilcon A with current process), Test Lenses (comfilcon A with novel process)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
5
States / cities
Berkeley, California • Bloomington, Indiana • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Rotation With a Multifocal Toric Contact Lens

NCT05433571
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Objective Vision Evaluation of Two Cosmetic Contact Lenses

NCT04287036
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Contact Lens, 1-DAY ACUVUE® DEFINE® Radiant Sweet™
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population

NCT04310566
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens (senofilcon A c3), Dailies Total 1® Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Pittsburg, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses

NCT04968925
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Precision 1
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
10
States / cities
Mission Viejo, California • Maitland, Florida • Orange Park, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

Senofilcon A Investigational Manufacturing Process

NCT01951703
View directory record Official record
Conditions
Visual Acuity, Comfort, Overall Vision
Interventions
senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
4
States / cities
Jacksonville, Florida • Bloomington, Illinois • Pittsburg, Kansas + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

A Multi-Center Study Comparing the Clinical Performance of Two Silicone Hydrogel Lenses Over 1 Month of Daily Wear

NCT01952665
View directory record Official record
Conditions
Myopia
Interventions
comfilcon A, lotrafilcon B
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
6
States / cities
Campbell, California • Whittier, California • Athens, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2017 · Synced Sep 3, 2026, 6:08 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Control of Myopia Using Novel Spectacle Lens Designs

NCT03623074
View directory record Official record
Conditions
Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 10 Years
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
13
States / cities
Whittier, California • Longwood, Florida • Pensacola, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 3, 2026, 6:08 PM EDT