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ClinicalTrials.gov public records Last synced Oct 19, 2026, 7:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 100 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Test Lens 2 Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population Phase 2

NCT03586648
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A Multifocal, senofilcon A Sphere, etafilcon A Multifocal, etafilcon A Sphere
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
6
States / cities
Whittier, California • Jacksonville, Florida • Maitland, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens

NCT04849780
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Habitual Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 59 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Silicone Hydrogel Multifocal Contact Lenses

NCT04093258
View directory record Official record
Conditions
Visual Acuity
Interventions
Dailies Total 1® Multifocal Contact Lenses, Air Optix® Multifocal Contact Lenses Plus HydraGlyde®
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Roswell, Georgia • Granville, Ohio • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Evaluation of Daily Disposable Toric Soft Contact Lenses Manufactured With an Alternative Hydration Process

NCT05427539
View directory record Official record
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Jacksonville, Florida • Maitland, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional

A Clinical Comparison of Proclear® 1 Day Multifocal and Clariti® 1 Day Multifocal 3 Add

NCT06869044
View directory record Official record
Conditions
Myopia, Hyperopia, Presbyopia
Interventions
omafilcon A lens, Low ADD power somofilcon A lens, Medium ADD power somofilcon A lens, High ADD power somofilcon A lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over Two Weeks of Wear

NCT06161012
View directory record Official record
Conditions
Ocular Physiology
Interventions
Senofilcon A contact lenses (TEST), Delefilcon A contact lenses (CONTROL)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Granville, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT05291936
View directory record Official record
Conditions
Ocular Physiology
Interventions
PRECISION1® for Astigmatism Contact Lenses, MyDay® Toric Soft Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Assessment of a Customized Free-form Progressive Addition Lens Spectacle

NCT01234207
View directory record Official record
Conditions
Presbyopia
Interventions
Standard, non-free-form, non-customized PAL spectacles, Individually customized free-form surfaced PAL spectacles
Device
Lead sponsor
University of California, Berkeley
Other
Eligibility
39 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Results available

Base-in Prism Spectacles for Intermittent Exotropia

NCT03998670
View directory record Official record
Conditions
Exotropia Intermittent
Interventions
Prism Glasses, Non-Prism Glasses
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 13 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
28
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Investigational Daily Disposable Multifocal Contact Lenses Produced With Different Manufacturing Processes in Myopes

NCT04889625
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A C3, Dailies Total 1® Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
6
States / cities
Jacksonville, Florida • Saint Augustine, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Results available

Evaluation Of One Silicone Hydrogel Contact Lens and Two Hydrogel Lenses in Daily Wear

NCT04050618
View directory record Official record
Conditions
Myopia
Interventions
fanfilcon A test lens, ocufilcon D control lens, etafilcon A control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
6
States / cities
Whittier, California • Longwood, Florida • Sarasota, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Reusable Soft Contact Lenses

NCT06119191
View directory record Official record
Conditions
Myopia
Interventions
Control Lenses (comfilcon A with current process), Test Lenses (comfilcon A with novel process)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
5
States / cities
Berkeley, California • Bloomington, Indiana • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens

NCT05927753
View directory record Official record
Conditions
Refractive Error - Myopia Bilateral
Interventions
Deseyne Daily Disposable Contact Lens (Test Device)
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
18 Years to 40 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 19, 2026, 7:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of the EpiGlare Tester for the Measurement of Glare-Induced Changes in BSCVA in Subjects With and Without Cataracts

NCT04739397
View directory record Official record
Conditions
Cataract
Interventions
Glare Testing
Device
Lead sponsor
Epico, LLC
Industry
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Oct 19, 2026, 7:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Approved Contact Lenses (CR-6657)

NCT07819305
View directory record Official record
Conditions
Visual Acuity
Interventions
Test (Senofilcon A), Control (Serafilcon A)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
8
States / cities
Jacksonville, Florida • Franklin Park, Illinois • Camden, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of ACUVUE OASYS® 1-Day for Astigmatism Lenses Produced on a New Manufacturing Line

NCT04794270
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE OASYS® 1-Day for Astigmatism - TAM 24, ACUVUE OASYS® 1-Day for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
5
States / cities
Longwood, Florida • Bloomington, Illinois • Pittsburg, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical and Laboratory Evaluation of 3 Contact Lenses With 4 Contact Lens Solutions

NCT01791517
View directory record Official record
Conditions
Contact Lens Solutions
Interventions
Solution 1 (Test), Solution 2 (Test), Solution 3 (Test), Solution 4 (Control)
Other
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population

NCT04310566
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens (senofilcon A c3), Dailies Total 1® Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Pittsburg, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control

NCT03635528
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens 1, Test Lens 2, Test Lens 3, Test Lens 4, Test Lens 5, Control Lens 1, Control Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 19, 2026, 7:41 AM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Evaluating Visual Acuity and Initial Fit Performance of Two Soft Contact Lenses

NCT04954833
View directory record Official record
Conditions
Visual Acuity
Interventions
EMO-200, EMO-118
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing the Performance of 1 Day Multifocal Contact Lenses

NCT04449263
View directory record Official record
Conditions
Presbyopia
Interventions
Lens A, Lens B, Habitual Lenses
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
5
States / cities
San Diego, California • Whittier, California • Sarasota, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Rotation With a Multifocal Toric Contact Lens

NCT05433571
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Results available

Spectacles for Patients With Down Syndrome

NCT03367793
View directory record Official record
Conditions
Vision, Low
Interventions
Spectacles - Clinically Derived, Spectacles - Metric Technique #1 Derived, Spectacles - Metric Technique #2 Derived
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Oct 19, 2026, 7:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Silicone Hydrogel Daily Disposable Contact Lenses

NCT02595502
View directory record Official record
Conditions
Vision Disorders
Interventions
JJVC Marketed Contact Lens (Test), Competitor Marketed Contact Lens (Control)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
286 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
13
States / cities
Montgomery, Alabama • Fruit Cove, Florida • Sarasota, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2017 · Synced Oct 19, 2026, 7:41 AM EDT