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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Tissue expander Clear all
Completed No phase listed Observational

Quantification of Breast Sensation Following Postmastectomy Breast Reconstruction

NCT00588419
View directory record Official record
Conditions
Breast Cancer, Cancer
Interventions
breast exam and questionaire
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older · Female only
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Sep 2, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Randomized Feasibility Trial for Mesh in Pre-Pectoral Reconstruction

NCT05190978
View directory record Official record
Conditions
Breast Cancer, Breast Implant; Complications, Infection or Inflammation
Interventions
Acellular Dermal Matrix, Reconstruction without ADM
Device · Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
22 Years to 75 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Regenerative Tissue Matrix for Breast Reconstruction

NCT01027637
View directory record Official record
Conditions
Breast Cancer
Interventions
5 mm vessel clips
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Sep 2, 2026, 1:27 AM EDT
Terminated Phase 4 Interventional Results available

Becker Continued Access Study

NCT01286870
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Mentor Becker 25 Expander/Breast Implant, Mentor Becker 50 Expander/Breast Implant
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Sep 2, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Pulsed Lavage in Implant-Based Breast Reconstruction

NCT05585710
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Pulsed Lavage Washout, Implant-based breast reconstruction, Bilateral or unilateral mastectomy, Tissue expander, Acellular dermal matrix
Other · Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 2, 2026, 1:27 AM EDT
Terminated Phase 4 Interventional

The Use of an Acellular Dermal Matrix in a Two-Staged Breast Reconstruction

NCT00616824
View directory record Official record
Conditions
Mastectomy, Postoperative Pain, Complications
Interventions
Dermamatrix to cover lateral aspect of tissue expander, Serratus anterior to cover lateral aspect of tissue expander
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Phase 4 Interventional Results available

PEMF and PEC Blocks in Mastectomy Reconstruction Patients

NCT03360214
View directory record Official record
Conditions
Breast Cancer Female
Interventions
Bupivacaine Hydrochloride, Placebo Drug, Pulsed Electromagnetic Field (PEMF) Device, Placebo Device, Ropivacaine Hydrochloride
Drug · Other · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Surgical Site Infection With 0.05% Chlorhexidine (CHG) Compared to Triple Antibiotic Irrigation

NCT02395614
View directory record Official record
Conditions
Breast Cancer
Interventions
Chlorhexidine irrigation, triple antibiotic irrigation
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 81 Years · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Sep 2, 2026, 1:27 AM EDT
Not listed Not applicable Interventional

Prevention of Capsular Contracture Using Trental and Vitamin E

NCT01082003
View directory record Official record
Conditions
Capsular Contractures
Interventions
Trental
Drug
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 27, 2013 · Synced Sep 2, 2026, 1:27 AM EDT
Recruiting Phase 4 Interventional

A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement

NCT07220967
View directory record Official record
Conditions
Breast Cancer
Interventions
Tissue Expander (TE), Vancomycin and Gentamicin, Stimulan Rapid Cure
Procedure · Drug · Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Delayed-Delayed Breast Reconstruction

NCT01256528
View directory record Official record
Conditions
Breast Cancer
Interventions
Delayed Breast Reconstruction
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2016 · Synced Sep 2, 2026, 1:27 AM EDT
Terminated Not applicable Interventional Results available

Closure of Fasciotomy Wounds: A Prospective, Observational Study of a Continuous External Tissue Expander

NCT01171534
View directory record Official record
Conditions
Wounds and Injuries, Compartment Syndrome
Interventions
DermaClose fasciotomy closure, Vessel loop
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 28, 2018 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Phase 3 Interventional

Tissue Expander/Implant Reconstruction: A Single-Blinded, Randomized, Controlled Trial

NCT00639106
View directory record Official record
Conditions
Breast Cancer
Interventions
Alloderm, Questionnaires, Without ALLODERM, Questionnaires
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years to 75 Years · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
3
States / cities
Ann Arbor, Michigan • New York, New York • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2018 · Synced Sep 2, 2026, 1:27 AM EDT
Terminated Phase 2 Interventional Results available

A Prospective Trial to Reduce Post-Operative Pain in Implant Based Breast Reconstruction

NCT02044302
View directory record Official record
Conditions
Post-operative Pain
Interventions
Bupivacaine, Botulinum Toxins, Analgesics
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

The Use of Pecs Blocks in Combination With Exparel in Breast Reconstruction Surgery

NCT05171179
View directory record Official record
Conditions
Mammaplasty
Interventions
Breast Reconstruction (Mammaplasty), Pecs blocks, Exparel, Bupivacaine
Procedure · Device · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Sep 2, 2026, 1:27 AM EDT
Not listed Phase 2 Interventional

Post-Mastectomy Analgesia Using Exparel (Liposomal) Versus Standard Bupivacaine or Placebo

NCT03504865
View directory record Official record
Conditions
Mastectomy, Breast Cancer
Interventions
Liposomal bupivacaine, Standard bupivacaine, Placebo
Drug · Other
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 26, 2020 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Reusable Versus Disposable Draping System in Breast Reconstruction Surgery

NCT01176786
View directory record Official record
Conditions
Mastectomy, Infections, Breast Reconstruction
Interventions
Culture Swabs, Rodac Plate Cultures
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Sep 2, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Assessment of the Interi Manifold in Implant-Based Breast Reconstruction

NCT05975359
View directory record Official record
Conditions
Mastectomy, Implant Based Breast Reconstruction
Interventions
Interi Manifold Drain System, Jackson Pratt Drain System
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 2, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™

NCT06649890
View directory record Official record
Conditions
Surgical Site Infection, Surgical Complication, Implant Infection, Implant Complication
Interventions
Xperience™ Advanced Surgical Irrigation, Dilute Povidone-Iodine
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Patient Controlled Tissue Expansion for Breast Reconstruction

NCT01425268
View directory record Official record
Conditions
Breast Cancer
Interventions
AeroForm Tissue Expansion, Saline Tissue Expansion
Device · Procedure
Lead sponsor
AirXpanders, Inc.
Industry
Eligibility
18 Years to 70 Years · Female only
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
17
States / cities
Greenbrae, California • Los Angeles, California • Orange, California + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Feasibility Study of Meso BioMatrix Device for Breast Reconstruction

NCT01823107
View directory record Official record
Conditions
Breast Cancer
Interventions
Meso BioMatrix Device
Device
Lead sponsor
Kensey Nash Corporation
Industry
Eligibility
21 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
6
States / cities
Detroit, Michigan • Garden City, New York • Bala-Cynwyd, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Pre-pectoral AlloDerm® to Reinforce Tissues in Tissue Expander Breast Reconstruction

NCT03195322
View directory record Official record
Conditions
Postoperative Pain, Postoperative Nausea and Vomiting, Quality of Life, Breast Cancer, Breast Prosthesis; Pain
Interventions
Pre-pectoral Tissue Expander
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Sep 2, 2026, 1:27 AM EDT
Completed Phase 4 Interventional Results available

Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Patient Undergoing Breast Reconstruction With Tissue Expander

NCT04278846
View directory record Official record
Conditions
Pain, Postoperative, Mammaplasty
Interventions
Depofoam bupivacaine, Bupivacaine hydrochloride (HCl)
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Sep 2, 2026, 1:27 AM EDT
Active, not recruiting Not applicable Interventional

A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction

NCT02724371
View directory record Official record
Conditions
Breast Reconstruction, Revision Breast Reconstruction
Interventions
Mentor Larger Size MemoryGel Ultra High Profile Breast Implant
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2029
U.S. locations
30
States / cities
Montgomery, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 2, 2026, 1:27 AM EDT