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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Tissue expander Clear all
Terminated Not applicable Interventional Results available

Use of Dermal Matrix in Breast Reconstruction

NCT00692692
View directory record Official record
Conditions
Breast Cancer
Interventions
DermaMatrix, standard of care tissue expander breast reconstruction surgery after mastectomy
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 18, 2018 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

Bioprosthetic Mesh to Expand the Lower Pole in Tissue Expander Reconstruction

NCT01310075
View directory record Official record
Conditions
Breast Cancer
Interventions
Alloderm, Surgimend
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Sep 3, 2026, 6:08 PM EDT
Withdrawn Not applicable Interventional

Patient Performed Tissue Expansion for Two-stage Alloplastic Breast Reconstruction

NCT04781907
View directory record Official record
Conditions
Tissue Expansion, Breast Reconstruction
Interventions
Tissue Expansion
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 27, 2024 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional

Delayed-Delayed Breast Reconstruction

NCT01256528
View directory record Official record
Conditions
Breast Cancer
Interventions
Delayed Breast Reconstruction
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2016 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Phase 1 Interventional

Bacterial Biofilms in Reconstructive Breast Prostheses Following Mastectomy

NCT03213249
View directory record Official record
Conditions
Breast Implant Infection, Mammoplasty
Interventions
Normal saline, Cefazolin, Skin biopsy, Bilateral skin- or nipple-sparing mastectomies, Tissue expander, Breast implant, Autologous flap, Acellular dermal matrix sling, Gentamicin, Bacitracin
Other · Drug · Procedure + 1 more
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Sep 3, 2026, 6:08 PM EDT
Withdrawn Not applicable Interventional

Effect of Externally Implantable Tissue Expansion Device on Scar Length

NCT00798798
View directory record Official record
Conditions
Skin Lesion
Interventions
Externally Implantable Tissue Expansion Device
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Sep 3, 2026, 6:08 PM EDT
Terminated Not applicable Interventional Results available

Management of Complex Wounds Using a Constant Tension External Tissue Expander

NCT01171521
View directory record Official record
Conditions
Wounds and Injuries
Interventions
DermaClose Group
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 25, 2016 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional Results available

Feasibility Study of Meso BioMatrix Device for Breast Reconstruction

NCT01823107
View directory record Official record
Conditions
Breast Cancer
Interventions
Meso BioMatrix Device
Device
Lead sponsor
Kensey Nash Corporation
Industry
Eligibility
21 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
6
States / cities
Detroit, Michigan • Garden City, New York • Bala-Cynwyd, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Phase 4 Interventional Results available

PEMF and PEC Blocks in Mastectomy Reconstruction Patients

NCT03360214
View directory record Official record
Conditions
Breast Cancer Female
Interventions
Bupivacaine Hydrochloride, Placebo Drug, Pulsed Electromagnetic Field (PEMF) Device, Placebo Device, Ropivacaine Hydrochloride
Drug · Other · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

The Use of Pecs Blocks in Combination With Exparel in Breast Reconstruction Surgery

NCT05171179
View directory record Official record
Conditions
Mammaplasty
Interventions
Breast Reconstruction (Mammaplasty), Pecs blocks, Exparel, Bupivacaine
Procedure · Device · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Sep 3, 2026, 6:08 PM EDT
Recruiting Not applicable Interventional

Assessment of the Interi Manifold in Implant-Based Breast Reconstruction

NCT05975359
View directory record Official record
Conditions
Mastectomy, Implant Based Breast Reconstruction
Interventions
Interi Manifold Drain System, Jackson Pratt Drain System
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional

Reusable Versus Disposable Draping System in Breast Reconstruction Surgery

NCT01176786
View directory record Official record
Conditions
Mastectomy, Infections, Breast Reconstruction
Interventions
Culture Swabs, Rodac Plate Cultures
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Sep 3, 2026, 6:08 PM EDT
Completed No phase listed Observational

Quantification of Breast Sensation Following Postmastectomy Breast Reconstruction

NCT00588419
View directory record Official record
Conditions
Breast Cancer, Cancer
Interventions
breast exam and questionaire
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older · Female only
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Sep 3, 2026, 6:08 PM EDT
Recruiting Not applicable Interventional

Safety and Feasibility of Robotic SP Nipple Sparing Mastectomy

NCT05245812
View directory record Official record
Conditions
Breast Cancer, High Risk of Breast Cancer
Interventions
da Vinci SP Surgical System
Device
Lead sponsor
Deborah Farr, MD
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 3, 2026, 6:08 PM EDT
Recruiting Phase 4 Interventional

A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement

NCT07220967
View directory record Official record
Conditions
Breast Cancer
Interventions
Tissue Expander (TE), Vancomycin and Gentamicin, Stimulan Rapid Cure
Procedure · Drug · Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 3, 2026, 6:08 PM EDT
Withdrawn Not applicable Interventional

Effectiveness of Acupuncture in Post-Mastectomy Patients With Tissue Expanders

NCT02639611
View directory record Official record
Conditions
Breast Cancer
Interventions
Immediate Post Operative Acupuncture Treatment, No Acupuncture Treatment
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 79 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 2, 2016 · Synced Sep 3, 2026, 6:08 PM EDT
Terminated No phase listed Observational

DermaClose DUKE Fasciotomy and Wound Study

NCT05330767
View directory record Official record
Conditions
Wound of Skin
Interventions
DermaClose Continuous External Tissue Expander Device, DermaClose XL Continuous External Tissue Expander Device, Conventional wound dressings
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Not applicable Interventional

Prospective Trial of Subcutaneous Versus Subpectoral 2-Staged Implant-Based Breast Reconstruction

NCT02775409
View directory record Official record
Conditions
Breast Reconstruction Following Mastectomy
Interventions
Subcutaneous placement, Submuscular placement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 29, 2021 · Synced Sep 3, 2026, 6:08 PM EDT
Completed No phase listed Observational

Tissue Expansion in Breast Reconstruction Without Drains

NCT03784859
View directory record Official record
Conditions
Breast Cancer, Hereditary Breast and Ovarian Cancer Syndrome, Breast Implant; Complications
Interventions
Insertion of Tissue Expander with Fluid Reservoir
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Sep 3, 2026, 6:08 PM EDT
Terminated Not applicable Interventional Results available

Liposomal Bupivacaine in Implant Based Breast Reconstruction

NCT02659501
View directory record Official record
Conditions
Breast Cancer, Postoperative Pain
Interventions
Liposomal bupivacaine, Bupivacaine with epinephrine, Morphine sulfate, Hydrocodone/acetaminophen, Diazepam
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Sep 3, 2026, 6:08 PM EDT
Not listed Phase 2 Interventional

Post-Mastectomy Analgesia Using Exparel (Liposomal) Versus Standard Bupivacaine or Placebo

NCT03504865
View directory record Official record
Conditions
Mastectomy, Breast Cancer
Interventions
Liposomal bupivacaine, Standard bupivacaine, Placebo
Drug · Other
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 26, 2020 · Synced Sep 3, 2026, 6:08 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Trial of Drain Antisepsis After Tissue Expander Breast Reconstruction

NCT01286168
View directory record Official record
Conditions
Nonmalignant Breast Conditions, Breast Cancer
Interventions
Sodium hypochlorite (Dakin's Solution), Chlorhexidine gluconate disk, Control, Occlusive Adhesive Dressing
Device · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
San Francisco, California • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 18, 2014 · Synced Sep 3, 2026, 6:08 PM EDT
Recruiting Not applicable Interventional

Pulsed Lavage in Implant-Based Breast Reconstruction

NCT05585710
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Pulsed Lavage Washout, Implant-based breast reconstruction, Bilateral or unilateral mastectomy, Tissue expander, Acellular dermal matrix
Other · Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 3, 2026, 6:08 PM EDT
Not listed Not applicable Interventional

Breast Mesh Used in Two-staged Breast Reconstruction

NCT04967976
View directory record Official record
Conditions
Breast Cancer, Radiation, Breast Reconstruction, Synthetic Mesh
Interventions
TiLoop Bra mesh in expander-implant breast reconstrution, sub-pectoral expander-implant breast reconstruction
Procedure
Lead sponsor
Tianjin Medical University Cancer Institute and Hospital
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Sep 3, 2026, 6:08 PM EDT